Muscarinic receptor signaling in the pathophysiology of asthma and COPD R Gosens, J Zaagsma, H Meurs, AJ Halayko Respiratory research 7, 1-15, 2006 | 577 | 2006 |
Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma SS An, TR Bai, JHT Bates, JL Black, RH Brown, V Brusasco, P Chitano, ... European Respiratory Journal 29 (5), 834-860, 2007 | 531 | 2007 |
Protective effects of tiotropium bromide in the progression of airway smooth muscle remodeling R Gosens, IST Bos, J Zaagsma, H Meurs American journal of respiratory and critical care medicine 171 (10), 1096-1102, 2005 | 310 | 2005 |
Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: a comparison IST Bos, R Gosens, AB Zuidhof, D Schaafsma, AJ Halayko, H Meurs, ... European Respiratory Journal 30 (4), 653-661, 2007 | 270 | 2007 |
Role of caveolin-1 in p42/p44 MAP kinase activation and proliferation of human airway smooth muscle R Gosens, GL Stelmack, G Dueck, KD McNeill, A Yamasaki, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 291 (3 …, 2006 | 241 | 2006 |
Airway structural components drive airway smooth muscle remodeling in asthma BGJ Dekkers, H Maarsingh, H Meurs, R Gosens Proceedings of the American Thoracic Society 6 (8), 683-692, 2009 | 221 | 2009 |
The WNT signaling pathway from ligand secretion to gene transcription: molecular mechanisms and pharmacological targets HA Baarsma, M Königshoff, R Gosens Pharmacology & therapeutics 138 (1), 66-83, 2013 | 213 | 2013 |
Activation of WNT / β-Catenin Signaling in Pulmonary Fibroblasts by TGF-β1 Is Increased in Chronic Obstructive Pulmonary Disease HA Baarsma, AIR Spanjer, G Haitsma, LHJM Engelbertink, H Meurs, ... PloS one 6 (9), e25450, 2011 | 202 | 2011 |
Airway hyperresponsiveness in asthma: lessons from in vitro model systems and animal models H Meurs, R Gosens, J Zaagsma European Respiratory Journal 32 (2), 487-502, 2008 | 175 | 2008 |
Paving the Rho in cancer metastasis: Rho GTPases and beyond S Jansen, R Gosens, T Wieland, M Schmidt Pharmacology & therapeutics 183, 1-21, 2018 | 173 | 2018 |
WNT-5A: signaling and functions in health and disease K Kumawat, R Gosens Cellular and Molecular Life Sciences 73, 567-587, 2016 | 170 | 2016 |
Acetylcholine beyond bronchoconstriction: roles in inflammation and remodeling LEM Kistemaker, R Gosens Trends in pharmacological sciences 36 (3), 164-171, 2015 | 169 | 2015 |
Phenotype and functional plasticity of airway smooth muscle: role of caveolae and caveolins AJ Halayko, T Tran, R Gosens Proceedings of the American Thoracic Society 5 (1), 80-88, 2008 | 159 | 2008 |
Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD T Pera, A Zuidhof, J Valadas, M Smit, RG Schoemaker, R Gosens, ... European Respiratory Journal 38 (4), 789-796, 2011 | 152 | 2011 |
Alternative mechanisms for tiotropium ED Bateman, S Rennard, PJ Barnes, PV Dicpinigaitis, R Gosens, ... Pulmonary pharmacology & therapeutics 22 (6), 533-542, 2009 | 152 | 2009 |
Noncanonical WNT‐5A signaling regulates TGF‐β‐induced extracellular matrix production by airway smooth muscle cells K Kumawat, MH Menzen, IST Bos, HA Baarsma, P Borger, M Roth, ... The FASEB Journal 27 (4), 1631-1643, 2013 | 148 | 2013 |
Reduced vitamin K status as a potentially modifiable risk factor of severe coronavirus disease 2019 ASM Dofferhoff, I Piscaer, LJ Schurgers, MPJ Visser, ... Clinical Infectious Diseases 73 (11), e4039-e4046, 2021 | 137 | 2021 |
The genetics of asthma and the promise of genomics-guided drug target discovery ZW El-Husseini, R Gosens, F Dekker, GH Koppelman The Lancet Respiratory Medicine 8 (10), 1045-1056, 2020 | 133 | 2020 |
The mode of action of anticholinergics in asthma R Gosens, N Gross European Respiratory Journal 52 (4), 2018 | 131 | 2018 |
Acetylcholine: a novel regulator of airway smooth muscle remodelling? R Gosens, J Zaagsma, MG Bromhaar, A Nelemans, H Meurs European journal of pharmacology 500 (1-3), 193-201, 2004 | 130 | 2004 |