Regulation of JNK signaling by GSTp V Adler, Z Yin, SY Fuchs, M Benezra, L Rosario, KD Tew, MR Pincus, ... The EMBO journal, 1999 | 1373 | 1999 |
The Cap ‘n’Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification … M McMahon, K Itoh, M Yamamoto, SA Chanas, CJ Henderson, ... Cancer research 61 (8), 3299-3307, 2001 | 807 | 2001 |
Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and … SA Chanas, Q Jiang, M McMahon, GK McWalter, LI McLellan, ... Biochemical Journal 365 (2), 405-416, 2002 | 526 | 2002 |
Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases CJ Henderson, AG Smith, J Ure, K Brown, EJ Bacon, CR Wolf Proceedings of the National Academy of Sciences 95 (9), 5275-5280, 1998 | 468 | 1998 |
Feedback control of AHR signalling regulates intestinal immunity C Schiering, E Wincent, A Metidji, A Iseppon, Y Li, AJ Potocnik, ... Nature 542 (7640), 242-245, 2017 | 452 | 2017 |
Uptake and effects of orally ingested polystyrene microplastic particles in vitro and in vivo V Stock, L Böhmert, E Lisicki, R Block, J Cara-Carmona, LK Pack, R Selb, ... Archives of toxicology 93, 1817-1833, 2019 | 425 | 2019 |
The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic … JD Hayes, SA Chanas, CJ Henderson, M McMahon, C Sun, GJ Moffat, ... Biochemical Society Transactions 28 (2), 33-41, 2000 | 418 | 2000 |
Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha XJ Wang, JD Hayes, CJ Henderson, CR Wolf Proceedings of the National Academy of Sciences 104 (49), 19589-19594, 2007 | 340 | 2007 |
Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase CJ Henderson, DME Otto, D Carrie, MA Magnuson, AW McLaren, ... Journal of Biological Chemistry 278 (15), 13480-13486, 2003 | 302 | 2003 |
Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans [S] S Takahashi, T Fukami, Y Masuo, CN Brocker, C Xie, KW Krausz, CR Wolf, ... Journal of lipid research 57 (12), 2130-2137, 2016 | 292 | 2016 |
Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics LM Forrester, CJ Henderson, MJ Glancey, DJ Back, BK Park, SE Ball, ... Biochemical Journal 281 (2), 359-368, 1992 | 289 | 1992 |
Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi CJ Henderson, CR Wolf, N Kitteringham, H Powell, D Otto, BK Park Proceedings of the National Academy of Sciences 97 (23), 12741-12745, 2000 | 282 | 2000 |
Transcription factor Nrf2 is essential for induction of NAD (P) H: quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and … GK McWalter, LG Higgins, LI McLellan, CJ Henderson, JD Hayes, L Song, ... The Journal of nutrition 134 (12), 3499S-3506S, 2004 | 251 | 2004 |
Identification of P450 enzymes involved in metabolism of verapamil in humans HK Kroemer, JC Gautier, P Beaune, C Henderson, C Roland Wolf, ... Naunyn-Schmiedeberg's archives of pharmacology 348, 332-337, 1993 | 243 | 1993 |
Pharmacologic or genetic manipulation of glutathione S-transferase P1–1 (GSTπ) influences cell proliferation pathways JE Ruscoe, LA Rosario, T Wang, L Gaté, P Arifoglu, CR Wolf, ... Journal of Pharmacology and Experimental Therapeutics 298 (1), 339-345, 2001 | 242 | 2001 |
Identification of novel roles of the cytochrome P450 system in early embryogenesis: effects on vasculogenesis and retinoic acid homeostasis DME Otto, CJ Henderson, D Carrie, M Davey, TE Gundersen, R Blomhoff, ... Molecular and cellular biology 23 (17), 6103-6116, 2003 | 209 | 2003 |
Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi R Elsby, NR Kitteringham, CE Goldring, CA Lovatt, M Chamberlain, ... Journal of Biological Chemistry 278 (25), 22243-22249, 2003 | 183 | 2003 |
High variability of nitrosamine metabolism among individuals: Role of cytochromes P450 2A6 and 2E1 in the dealkylation of N‐nitrosodimethylamine and N‐nitrosodiethylamine in … AM Camus, O Geneste, P Honkakoski, JC Béréziat, CJ Henderson, ... Molecular carcinogenesis 7 (4), 268-275, 1993 | 182 | 1993 |
Pi-class glutathione S-transferase: regulation and function CJ Henderson, AW McLaren, GJ Moffat, EJ Bacon, CR Wolf Chemico-Biological Interactions 111, 69-82, 1998 | 176 | 1998 |
Metabolic activation of benzo [a] pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice VM Arlt, M Stiborova, CJ Henderson, M Thiemann, E Frei, D Aimova, ... Carcinogenesis 29 (3), 656-665, 2008 | 168 | 2008 |