| Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities M Hayn, M Hirschenberger, L Koepke, R Nchioua, JH Straub, S Klute, ... Cell reports 35 (7), 2021 | 208* | 2021 |
| IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro C Prelli Bozzo, R Nchioua, M Volcic, L Koepke, J Krüger, D Schütz, ... Nature communications 12 (1), 4584, 2021 | 175* | 2021 |
| SARS-CoV-2 is restricted by zinc finger antiviral protein despite preadaptation to the low-CpG environment in humans R Nchioua, D Kmiec, JA Müller, C Conzelmann, R Groß, CM Swanson, ... MBio 11 (5), 10.1128/mbio. 01930-20, 2020 | 126* | 2020 |
| SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3 U Tripathi, R Nchioua, LGPL Prata, Y Zhu, EOW Gerdes, N Giorgadze, ... Aging (albany NY) 13 (18), 21838, 2021 | 64 | 2021 |
| CpG Frequency in the 5′ Third of the env Gene Determines Sensitivity of Primary HIV-1 Strains to the Zinc-Finger Antiviral Protein D Kmiec, R Nchioua, S Sherrill-Mix, CM Stürzel, E Heusinger, E Braun, ... MBio 11 (1), 10.1128/mbio. 02903-19, 2020 | 52* | 2020 |
| Spike residue 403 affects binding of coronavirus spikes to human ACE2 F Zech, D Schniertshauer, C Jung, A Herrmann, A Cordsmeier, Q Xie, ... Nature Communications 12 (1), 6855, 2021 | 42 | 2021 |
| Actin cytoskeleton remodeling primes RIG-I-like receptor activation D Acharya, R Reis, M Volcic, GQ Liu, MK Wang, BS Chia, R Nchioua, ... Cell 185 (19), 3588-3602. e21, 2022 | 31 | 2022 |
| SARS-CoV-2 variants of concern remain dependent on IFITM2 for efficient replication in human lung cells (preprint) R Nchioua, A Schundner, D Kmiec, C Prelli-Bozzo, F Zech, L Koepke, ... | 26* | 2021 |
| Cellular factors targeting HIV-1 transcription and viral RNA transcripts R Nchioua, M Bosso, D Kmiec, F Kirchhoff Viruses 12 (5), 495, 2020 | 24 | 2020 |
| Strong attenuation of SARS-CoV-2 Omicron BA. 1 and increased replication of the BA. 5 subvariant in human cardiomyocytes R Nchioua, F Diofano, S Noettger, P von Maltitz, S Stenger, F Zech, ... Signal Transduction and Targeted Therapy 7 (1), 395, 2022 | 20 | 2022 |
| Reduced replication but increased interferon resistance of SARS-CoV-2 Omicron BA. 1 R Nchioua, A Schundner, S Klute, L Koepke, M Hirschenberger, ... Life science alliance 6 (6), 2023 | 18* | 2023 |
| Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques TN Hoang, EG Viox, AA Upadhyay, Z Strongin, GK Tharp, M Pino, ... bioRxiv, 2022 | 13* | 2022 |
| Endogenous IFITMs boost SARS-coronavirus 1 and 2 replication whereas overexpression inhibits infection by relocalizing ACE2 Q Xie, CP Bozzo, L Eiben, S Noettger, D Kmiec, R Nchioua, D Niemeyer, ... Iscience 26 (4), 2023 | 7 | 2023 |
| APOBEC3F Constitutes a Barrier to Successful Cross-Species Transmission of Simian Immunodeficiency Virus SIVsmm to Humans R Nchioua, D Kmiec, A Gaba, CM Stürzel, T Follack, S Patrick, A Kirmaier, ... Journal of Virology 95 (17), 10.1128/jvi. 00808-21, 2021 | 4 | 2021 |
| Tetherin Restricts SARS-CoV-2 despite the Presence of Multiple Viral Antagonists E Hagelauer, R Lotke, D Kmiec, D Hu, M Hohner, S Stopper, R Nchioua, ... Viruses 15 (12), 2364, 2023 | 2 | 2023 |
| Making Cell Culture More Physiological: Serially passaged, conditionally reprogrammed nasal epithelial cells as a model to study epithelial functions and SARS-CoV-2 infection H Schmidt, L Guthjahr, A Sauter, F Zech, R Nchioua, S Stenger, M Frick, ... American Journal of Physiology-Cell Physiology 322 (4), C591, 2022 | 2* | 2022 |
| Attenuated replication and damaging effects of SARS-CoV-2 Omicron in an intestinal epithelial barrier model M Volcic, R Nchioua, C Pastorio, F Zech, C Read, P Walther, F Kirchhoff bioRxiv, 2024.02. 28.582510, 2024 | 1 | 2024 |
| Impact of mutations defining SARS-CoV-2 Omicron subvariants BA. 2.12. 1 and BA. 4/5 on Spike function and neutralization C Pastorio, S Noettger, R Nchioua, F Zech, KMJ Sparrer, F Kirchhoff Iscience 26 (11), 2023 | 1 | 2023 |
| A Gaussia luciferase reporter assay for the evaluation of coronavirus Nsp5/3CLpro inhibitors A Vlachou, R Nchioua, K Regensburger, F Kirchhoff, D Kmiec | | 2024 |
| SARS-CoV-2 Omicron Envelope T9I adaptation confers resistance to autophagy S Klute, R Nchioua, A Cordsmeier, J Vishwakarma, L Koepke, ... bioRxiv, 2024.04. 23.590789, 2024 | | 2024 |
