Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer C Fumarola, MA Bonelli, PG Petronini, RR Alfieri Biochemical pharmacology 90 (3), 197-207, 2014 | 427 | 2014 |
Low PD-1 Expression in Cytotoxic CD8+ Tumor-Infiltrating Lymphocytes Confers an Immune-Privileged Tissue Microenvironment in NSCLC with a Prognostic and … G Mazzaschi, D Madeddu, A Falco, G Bocchialini, M Goldoni, F Sogni, ... Clinical cancer research 24 (2), 407-419, 2018 | 208 | 2018 |
Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells1 M Brigotti, R Alfieri, P Sestili, M Bonelli, PG Petronini, A Guidarelli, ... The FASEB Journal 16 (3), 365-372, 2002 | 183 | 2002 |
Hyperosmotic stress response: comparison with other cellular stresses RR Alfieri, PG Petronini Pflügers Archiv-European Journal of Physiology 454, 173-185, 2007 | 130 | 2007 |
5-Benzylidene-hydantoins as new EGFR inhibitors with antiproliferative activity C Carmi, A Cavazzoni, V Zuliani, A Lodola, F Bordi, PV Plazzi, RR Alfieri, ... Bioorganic & medicinal chemistry letters 16 (15), 4021-4025, 2006 | 120 | 2006 |
The translational machinery of human CD4+ T cells is poised for activation and controls the switch from quiescence to metabolic remodeling S Ricciardi, N Manfrini, R Alfieri, P Calamita, MC Crosti, S Gallo, R Müller, ... Cell metabolism 28 (6), 895-906. e5, 2018 | 119 | 2018 |
Compatible osmolytes modulate the response of porcine endothelial cells to hypertonicity and protect them from apoptosis RR Alfieri, A Cavazzoni, PG Petronini, MA Bonelli, AE Caccamo, ... The Journal of Physiology 540 (2), 499-508, 2002 | 113 | 2002 |
Clinical perspectives for irreversible tyrosine kinase inhibitors in cancer C Carmi, M Mor, PG Petronini, RR Alfieri Biochemical pharmacology 84 (11), 1388-1399, 2012 | 107 | 2012 |
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones A Cavazzoni, MA Bonelli, C Fumarola, S La Monica, K Airoud, R Bertoni, ... Cancer letters 323 (1), 77-87, 2012 | 105 | 2012 |
Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines S La Monica, M Galetti, RR Alfieri, A Cavazzoni, A Ardizzoni, M Tiseo, ... Biochemical pharmacology 78 (5), 460-468, 2009 | 97 | 2009 |
Synthesis and biological evaluation of tetracyclic fluoroquinolones as antibacterial and anticancer agents SA Al-Trawneh, JA Zahra, MR Kamal, MM El-Abadelah, F Zani, M Incerti, ... Bioorganic & medicinal chemistry 18 (16), 5873-5884, 2010 | 91 | 2010 |
Combined inhibition of CDK4/6 and PI3K/AKT/mTOR pathways induces a synergistic anti-tumor effect in malignant pleural mesothelioma cells MA Bonelli, G Digiacomo, C Fumarola, R Alfieri, F Quaini, A Falco, ... Neoplasia 19 (8), 637-648, 2017 | 90 | 2017 |
Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress RR Alfieri, MA Bonelli, A Cavazzoni, M Brigotti, C Fumarola, P Sestili, ... The Journal of physiology 576 (2), 391-401, 2006 | 88 | 2006 |
Cell size reduction induced by inhibition of the mTOR/S6K-signaling pathway protects Jurkat cells from apoptosis C Fumarola, S La Monica, RR Alfieri, E Borra, GG Guidotti Cell Death & Differentiation 12 (10), 1344-1357, 2005 | 85 | 2005 |
Tumor-infiltrating lymphocytes and breast cancer: beyond the prognostic and predictive utility A Ravelli, G Roviello, D Cretella, A Cavazzoni, A Biondi, MR Cappelletti, ... Tumor Biology 39 (4), 1010428317695023, 2017 | 81 | 2017 |
Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines A Cavazzoni, RR Alfieri, C Carmi, V Zuliani, M Galetti, C Fumarola, ... Molecular cancer therapeutics 7 (2), 361-370, 2008 | 79 | 2008 |
Effects of osmolarity, ions and compatible osmolytes on cell-free protein synthesis M Brigotti, PG Petronini, D Carnicelli, RR Alfieri, MA Bonelli, AF Borghetti, ... Biochemical Journal 369 (2), 369-374, 2003 | 77 | 2003 |
FGFR as potential target in the treatment of squamous non small cell lung cancer M Tiseo, F Gelsomino, R Alfieri, A Cavazzoni, C Bozzetti, AM De Giorgi, ... Cancer treatment reviews 41 (6), 527-539, 2015 | 75 | 2015 |
Novel irreversible epidermal growth factor receptor inhibitors by chemical modulation of the cysteine-trap portion C Carmi, A Cavazzoni, S Vezzosi, F Bordi, F Vacondio, C Silva, S Rivara, ... Journal of medicinal chemistry 53 (5), 2038-2050, 2010 | 75 | 2010 |
Cell susceptibility to apoptosis by glutamine deprivation and rescue: Survival and apoptotic death in cultured lymphoma‐leukemia cell lines PG Petronini, S Urbani, R Alfieri, AF Borghetti, GG Guidotti Journal of cellular physiology 169 (1), 175-185, 1996 | 75 | 1996 |