A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy PG Komarov, EA Komarova, RV Kondratov, K Christov-Tselkov, JS Coon, ... Science 285 (5434), 1733-1737, 1999 | 1511 | 1999 |
An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models LG Burdelya, VI Krivokrysenko, TC Tallant, E Strom, AS Gleiberman, ... Science 320 (5873), 226-230, 2008 | 887 | 2008 |
The role of p53 in determining sensitivity to radiotherapy AV Gudkov, EA Komarova Nature Reviews Cancer 3 (2), 117-129, 2003 | 745 | 2003 |
Structural basis of TLR5-flagellin recognition and signaling S Yoon, O Kurnasov, V Natarajan, M Hong, AV Gudkov, AL Osterman, ... Science 335 (6070), 859-864, 2012 | 604 | 2012 |
Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation I Garkavtsev, A Kazarov, A Gudkov, K Riabowol Nature genetics 14 (4), 415-420, 1996 | 534 | 1996 |
The candidate tumour suppressor p33ING1cooperates with p53 in cell growth control I Garkavtsev, IA Grigorian, VS Ossovskaya, MV Chernov, PM Chumakov, ... Nature 391 (6664), 295-298, 1998 | 474 | 1998 |
Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53 SS Bacus, AV Gudkov, M Lowe, L Lyass, Y Yung, AP Komarov, ... Oncogene 20 (2), 147-155, 2001 | 437 | 2001 |
Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability AV Budanov, T Shoshani, A Faerman, E Zelin, I Kamer, H Kalinski, ... Oncogene 21 (39), 6017-6031, 2002 | 426 | 2002 |
Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation E Strom, S Sathe, PG Komarov, OB Chernova, I Pavlovska, I Shyshynova, ... Nature chemical biology 2 (9), 474-479, 2006 | 398 | 2006 |
Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo EA Komarova, MV Chernov, R Franks, K Wang, G Armin, CR Zelnick, ... The EMBO journal 16 (6), 1391-1400, 1997 | 355 | 1997 |
LINE1 derepression in aged wild-type and SIRT6-deficient mice drives inflammation M Simon, M Van Meter, J Ablaeva, Z Ke, RS Gonzalez, T Taguchi, ... Cell metabolism 29 (4), 871-885. e5, 2019 | 354 | 2019 |
Aging of mice is associated with p16 (Ink4a)-and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells BM Hall, V Balan, AS Gleiberman, E Strom, P Krasnov, LP Virtuoso, ... Aging (Albany NY) 8 (7), 1294, 2016 | 352 | 2016 |
Regulation of NF-κB by NSD1/FBXL11-dependent reversible lysine methylation of p65 T Lu, MW Jackson, B Wang, M Yang, MR Chance, M Miyagi, AV Gudkov, ... Proceedings of the National Academy of Sciences 107 (1), 46-51, 2010 | 329 | 2010 |
Core circadian protein CLOCK is a positive regulator of NF-κB–mediated transcription ML Spengler, KK Kuropatwinski, M Comas, AV Gasparian, N Fedtsova, ... Proceedings of the National Academy of Sciences 109 (37), E2457-E2465, 2012 | 321 | 2012 |
The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway LG Korotchkina, OV Leontieva, EI Bukreeva, ZN Demidenko, AV Gudkov, ... Aging (Albany NY) 2 (6), 344, 2010 | 313 | 2010 |
Paradoxical suppression of cellular senescence by p53 ZN Demidenko, LG Korotchkina, AV Gudkov, MV Blagosklonny Proceedings of the National Academy of Sciences 107 (21), 9660-9664, 2010 | 306 | 2010 |
Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex VY Gorbacheva, RV Kondratov, R Zhang, S Cherukuri, AV Gudkov, ... Proceedings of the National Academy of Sciences 102 (9), 3407-3412, 2005 | 304 | 2005 |
p16 (Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli BM Hall, V Balan, AS Gleiberman, E Strom, P Krasnov, LP Virtuoso, ... Aging (Albany NY) 9 (8), 1867, 2017 | 302 | 2017 |
BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system RV Kondratov, MV Chernov, AA Kondratova, VY Gorbacheva, AV Gudkov, ... Genes & development 17 (15), 1921-1932, 2003 | 301 | 2003 |
Small molecules that reactivate p53 in renal cell carcinoma reveal a NF-κB-dependent mechanism of p53 suppression in tumors KV Gurova, JE Hill, C Guo, A Prokvolit, LG Burdelya, E Samoylova, ... Proceedings of the National Academy of Sciences 102 (48), 17448-17453, 2005 | 297 | 2005 |