The miRNome of Alzheimer's disease: consistent downregulation of the miR-132/212 cluster S Pichler, W Gu, D Hartl, G Gasparoni, P Leidinger, A Keller, E Meese, ... Neurobiology of aging 50, 167. e1-167. e10, 2017 | 134 | 2017 |
The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain AS Carlo, C Gustafsen, G Mastrobuoni, MS Nielsen, T Burgert, D Hartl, ... Journal of Neuroscience 33 (1), 358-370, 2013 | 113 | 2013 |
A large number of protein expression changes occur early in life and precede phenotype onset in a mouse model for Huntington disease* S C Zabel, L Mao, B Woodman, M Rohe, MA Wacker, Y Klare, ... Molecular & Cellular Proteomics 8 (4), 720-734, 2009 | 88 | 2009 |
Transcriptome and proteome analysis of early embryonic mouse brain development D Hartl, M Irmler, I Römer, MT Mader, L Mao, C Zabel, MH de Angelis, ... Proteomics 8 (6), 1257-1265, 2008 | 71 | 2008 |
A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease D Hartl, P May, W Gu, M Mayhaus, S Pichler, C Spaniol, E Glaab, ... Molecular psychiatry 25 (3), 629-639, 2020 | 60 | 2020 |
Proteasome and oxidative phoshorylation changes may explain why aging is a risk factor for neurodegenerative disorders C Zabel, HP Nguyen, SC Hin, D Hartl, L Mao, J Klose Journal of proteomics 73 (11), 2230-2238, 2010 | 53 | 2010 |
Soluble alpha-APP (sAPPalpha) regulates CDK5 expression and activity in neurons D Hartl, S Klatt, M Roch, Z Konthur, J Klose, TE Willnow, M Rohe PloS one 8 (6), e65920, 2013 | 47 | 2013 |
Presymptomatic alterations in energy metabolism and oxidative stress in the APP23 mouse model of Alzheimer disease D Hartl, V Schuldt, S Forler, C Zabel, J Klose, M Rohe Journal of proteome research 11 (6), 3295-3304, 2012 | 41 | 2012 |
SORLA-mediated trafficking of TrkB enhances the response of neurons to BDNF M Rohe, D Hartl, AN Fjorback, J Klose, TE Willnow PloS one 8 (8), e72164, 2013 | 40 | 2013 |
Production of Glycosylated Soluble Amyloid Precursor Protein Alpha (sAPPalpha) in Leishmania tarentolae S Klatt, M Rohe, K Alagesan, D Kolarich, Z Konthur, D Hartl Journal of proteome research 12 (1), 396-403, 2013 | 38 | 2013 |
Impairment of adolescent hippocampal plasticity in a mouse model for Alzheimer's disease precedes disease phenotype D Hartl, M Rohe, L Mao, M Staufenbiel, C Zabel, J Klose PloS one 3 (7), e2759, 2008 | 37 | 2008 |
An approach to handling and interpretation of ambiguous data in transcriptome and proteome comparisons M Irmler, D Hartl, T Schmidt, J Schuchhardt, C Lach, HE Meyer, ... Proteomics 8 (6), 1165-1169, 2008 | 32 | 2008 |
Proteomic shifts in embryonic stem cells with gene dose modifications suggest the presence of balancer proteins in protein regulatory networks L Mao, C Zabel, M Herrmann, T Nolden, F Mertes, L Magnol, C Chabert, ... PLoS One 2 (11), e1218, 2007 | 31 | 2007 |
Pronounced alterations of cellular metabolism and structure due to hyper-or hypo-osmosis L Mao, D Hartl, T Nolden, A Koppelstätter, J Klose, H Himmelbauer, ... Journal of proteome research 7 (9), 3968-3983, 2008 | 27 | 2008 |
Protein expression overlap: more important than which proteins change in expression? C Zabel, A Andreew, L Mao, D Hartl Expert Review of Proteomics 5 (2), 187-205, 2008 | 27 | 2008 |
Rare ABCA7 variants in 2 German families with Alzheimer disease P May, S Pichler, D Hartl, DR Bobbili, M Mayhaus, C Spaniol, A Kurz, ... Neurology: Genetics 4 (2), e224, 2018 | 18 | 2018 |
Aging in mouse brain is a cell/tissue-level phenomenon exacerbated by proteasome loss L Mao, I Römer, G Nebrich, O Klein, A Koppelstätter, SC Hin, D Hartl, ... Journal of proteome research 9 (7), 3551-3560, 2010 | 18 | 2010 |
Identification of novel biomarkers in chronic immune thrombocytopenia (ITP) by microarray‐based serum protein profiling G Bal, ME Futschik, D Hartl, F Ringel, J Kamhieh‐Milz, V Sterzer, ... British journal of haematology 172 (4), 602-615, 2016 | 17 | 2016 |
Double NF1 inactivation affects adrenocortical function in NF1Prx1 mice and a human patient K Kobus, D Hartl, CE Ott, M Osswald, A Huebner, M von der Hagen, ... PLoS One 10 (3), e0119030, 2015 | 15 | 2015 |
SORLA regulates calpain-dependent degradation of synapsin D Hartl, G Nebrich, O Klein, H Stephanowitz, E Krause, M Rohe Alzheimer's & Dementia 12 (9), 952-963, 2016 | 13 | 2016 |