| Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy TC Thannickal, J John, L Shan, DF Swaab, MF Wu, L Ramanathan, ... Science translational medicine 10 (447), eaao4953, 2018 | 120 | 2018 |
| The human histaminergic system in neuropsychiatric disorders L Shan, AM Bao, DF Swaab Trends in neurosciences 38 (3), 167-177, 2015 | 109 | 2015 |
| Interactions of the histamine and hypocretin systems in CNS disorders L Shan, Y Dauvilliers, JM Siegel Nature reviews Neurology 11 (7), 401-413, 2015 | 106 | 2015 |
| Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson's patients: a postmortem study L Shan, K Bossers, S Luchetti, R Balesar, N Lethbridge, PL Chazot, ... Neurobiology of aging 33 (7), 1488. e1-1488. e13, 2012 | 78 | 2012 |
| Alterations in the histaminergic system in Alzheimer's disease: a postmortem study L Shan, K Bossers, U Unmehopa, AM Bao, DF Swaab Neurobiology of aging 33 (11), 2585-2598, 2012 | 73 | 2012 |
| An endoplasmic reticulum retention signal located in the extracellular amino-terminal domain of the NR2A subunit of N-Methyl-D-aspartate receptors S Qiu, X Zhang, J Cao, W Yang, Y Yan, L Shan, J Zheng, J Luo Journal of Biological Chemistry 284 (30), 20285-20298, 2009 | 68 | 2009 |
| Gestational factors throughout fetal neurodevelopment: the serotonin link SI Hanswijk, M Spoelder, L Shan, MMM Verheij, OG Muilwijk, W Li, C Liu, ... International journal of molecular sciences 21 (16), 5850, 2020 | 64 | 2020 |
| Presence of tissue transglutaminase in granular endoplasmic reticulum is characteristic of melanized neurons in Parkinson's disease brain MMM Wilhelmus, R Verhaar, G Andringa, JGJM Bol, P Cras, L Shan, ... Brain pathology 21 (2), 130-139, 2011 | 64 | 2011 |
| The role of the dopamine D1 receptor in social cognition: studies using a novel genetic rat model JR Homberg, JDA Olivier, M VandenBroeke, J Youn, AK Ellenbroek, ... Disease models & mechanisms 9 (10), 1147-1158, 2016 | 53 | 2016 |
| Functional increase of brain histaminergic signaling in Huntington's disease DJ van Wamelen, L Shan, NA Aziz, JJ Anink, AM Bao, RAC Roos, ... Brain pathology 21 (4), 419-427, 2011 | 50 | 2011 |
| Diurnal fluctuation in the number of hypocretin/orexin and histamine producing: implication for understanding and treating neuronal loss R McGregor, L Shan, MF Wu, JM Siegel PloS one 12 (6), e0178573, 2017 | 47 | 2017 |
| Diurnal fluctuation in histidine decarboxylase expression, the rate limiting enzyme for histamine production, and its disorder in neurodegenerative diseases L Shan, MA Hofman, DJ Van Wamelen, EJW Van Someren, AM Bao, ... Sleep 35 (5), 713-715, 2012 | 47 | 2012 |
| Neuronal histamine production remains unaltered in Parkinson's disease despite the accumulation of Lewy bodies and Lewy neurites in the tuberomamillary nucleus L Shan, CQ Liu, R Balesar, MA Hofman, AM Bao, DF Swaab Neurobiology of aging 33 (7), 1343-1344, 2012 | 41 | 2012 |
| Neuronal histaminergic system in aging and age-related neurodegenerative disorders L Shan, DF Swaab, AM Bao Experimental gerontology 48 (7), 603-607, 2013 | 40 | 2013 |
| Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model P Zhou, JR Homberg, Q Fang, J Wang, W Li, X Meng, J Shen, Y Luan, ... Brain, behavior, and immunity 76, 61-73, 2019 | 38 | 2019 |
| Impaired fear extinction as displayed by serotonin transporter knockout rats housed in open cages is disrupted by IVC cage housing L Shan, P Schipper, LJP Nonkes, JR Homberg PloS one 9 (3), e91472, 2014 | 34 | 2014 |
| Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy A Seifinejad, M Ramosaj, L Shan, S Li, ML Possovre, C Pfister, ... Proceedings of the National Academy of Sciences 120 (19), e2220911120, 2023 | 29 | 2023 |
| Astrocyte changes in the prefrontal cortex from aged non-suicidal depressed patients XR Qi, W Kamphuis, L Shan Frontiers in Cellular Neuroscience 13, 503, 2019 | 26 | 2019 |
| Histamine-4 receptor antagonist ameliorates Parkinson-like pathology in the striatum Q Fang, H Xicoy, J Shen, S Luchetti, D Dai, P Zhou, XR Qi, GJM Martens, ... Brain, Behavior, and Immunity 92, 127-138, 2021 | 22 | 2021 |
| A quantitative in situ hybridization protocol for formalin-fixed paraffin-embedded archival post-mortem human brain tissue CQ Liu, L Shan, R Balesar, S Luchetti, JJ Van Heerikhuize, JH Luo, ... Methods 52 (4), 359-366, 2010 | 22 | 2010 |
Judith HombergAssociate professor在 radboudumc.nl 的电子邮件经过验证
