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Michael A Mastrangelo
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Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex …
MC Janelsins, MA Mastrangelo, S Oddo, FM LaFerla, HJ Federoff, ...
Journal of neuroinflammation 2 (1), 1-12, 2005
3192005
Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice
MA Mastrangelo, WJ Bowers
BMC neuroscience 9, 1-31, 2008
2902008
Triple‐transgenic Alzheimer's disease mice exhibit region‐specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology
MK Desai, KL Sudol, MC Janelsins, MA Mastrangelo, ME Frazer, ...
Glia 57 (1), 54-65, 2009
2792009
Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice
MC Janelsins, MA Mastrangelo, KM Park, KL Sudol, WC Narrow, S Oddo, ...
The American journal of pathology 173 (6), 1768-1782, 2008
2622008
Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target
MK Desai, MA Mastrangelo, DA Ryan, KL Sudol, WC Narrow, WJ Bowers
The American journal of pathology 177 (3), 1422-1435, 2010
2422010
Genome-wide association transethnic meta-analyses identifies novel associations regulating coagulation factor VIII and von Willebrand factor plasma levels
M Sabater-Lleal, JE Huffman, PS De Vries, J Marten, MA Mastrangelo, ...
Circulation 139 (5), 620-635, 2019
1302019
Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic …
SL Montgomery, MA Mastrangelo, D Habib, WC Narrow, SA Knowlden, ...
The American journal of pathology 179 (4), 2053-2070, 2011
1302011
Interferon-γ differentially affects Alzheimer’s disease pathologies and induces neurogenesis in triple transgenic-AD mice
MA Mastrangelo, KL Sudol, WC Narrow, WJ Bowers
The American journal of pathology 175 (5), 2076-2088, 2009
1102009
SIRT6 protects against endothelial dysfunction and atherosclerosis in mice
S Xu, M Yin, M Koroleva, MA Mastrangelo, W Zhang, P Bai, PJ Little, ...
Aging (Albany NY) 8 (5), 1064, 2016
1052016
Aβ-directed single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice
DA Ryan, MA Mastrangelo, WC Narrow, MA Sullivan, HJ Federoff, ...
Molecular Therapy 18 (8), 1471-1481, 2010
842010
Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS
JA Olschowka, WJ Bowers, SD Hurley, MA Mastrangelo, HJ Federoff
Molecular Therapy 7 (2), 218-227, 2003
802003
Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-β and interleukin-4
ME Frazer, JE Hughes, MA Mastrangelo, JL Tibbens, HJ Federoff, ...
Molecular Therapy 16 (5), 845-853, 2008
732008
Chronic neuron-and age-selective down-regulation of TNF receptor expression in triple-transgenic Alzheimer disease mice leads to significant modulation of amyloid-and Tau …
SL Montgomery, WC Narrow, MA Mastrangelo, JA Olschowka, ...
The American journal of pathology 182 (6), 2285-2297, 2013
682013
A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis
S Xu, B Liu, M Yin, M Koroleva, M Mastrangelo, S Ture, CN Morrell, ...
Oncotarget 7 (25), 37622, 2016
652016
Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector
WJ Bowers, MA Mastrangelo, DF Howard, HA Southerland, ...
Molecular Therapy 13 (3), 580-588, 2006
652006
The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function
JA Bennett, MA Mastrangelo, SK Ture, CO Smith, SG Loelius, RA Berg, ...
Nature Communications 11 (1), 3479, 2020
632020
Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis
R Domingo-Gonzalez, S Das, KL Griffiths, M Ahmed, M Bambouskova, ...
JCI insight 2 (19), 2017
612017
Generating differentially targeted amyloid-β specific intrabodies as a passive vaccination strategy for Alzheimer's disease
KL Sudol, MA Mastrangelo, WC Narrow, ME Frazer, YR Levites, TE Golde, ...
Molecular Therapy 17 (12), 2031-2040, 2009
572009
HSV amplicon-mediated Aβ vaccination in Tg2576 mice: differential antigen-specific immune responses
WJ Bowers, MA Mastrangelo, HA Stanley, AE Casey, LJ Milo Jr, ...
Neurobiology of aging 26 (4), 393-407, 2005
532005
Behavioral pharmacology of AR-A000002, a novel, selective 5-hydroxytryptamine1B antagonist
TJ Hudzik, M Yanek, T Porrey, J Evenden, C Paronis, M Mastrangelo, ...
Journal of Pharmacology and Experimental Therapeutics 304 (3), 1072-1084, 2003
522003
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