Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs C Swanton, M Marani, O Pardo, PH Warne, G Kelly, E Sahai, F Elustondo, ... Cancer cell 11 (6), 498-512, 2007 | 439 | 2007 |
Yes-associated protein (YAP) functions as a tumor suppressor in breast M Yuan, V Tomlinson, R Lara, D Holliday, C Chelala, T Harada, ... Cell Death & Differentiation 15 (11), 1752-1759, 2008 | 366 | 2008 |
FGF‐2 protects small cell lung cancer cells from apoptosis through a complex involving PKCε, B‐Raf and S6K2 OE Pardo, C Wellbrock, UK Khanzada, M Aubert, I Arozarena, S Davidson, ... The EMBO journal 25 (13), 3078-3088, 2006 | 231 | 2006 |
CUTL1 is a target of TGFβ signaling that enhances cancer cell motility and invasiveness P Michl, AR Ramjaun, OE Pardo, PH Warne, M Wagner, R Poulsom, ... Cancer cell 7 (6), 521-532, 2005 | 222 | 2005 |
Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis OE Pardo, A Arcaro, G Salerno, S Raguz, J Downward, MJ Seckl Journal of Biological Chemistry 277 (14), 12040-12046, 2002 | 208 | 2002 |
Oncogene-selective sensitivity to synchronous cell death following modulation of the amino acid nutrient cystine I Poursaitidis, X Wang, T Crighton, C Labuschagne, D Mason, SL Cramer, ... Cell reports 18 (11), 2547-2556, 2017 | 205 | 2017 |
The Fibroblast Growth Factor Receptor Inhibitor PD173074 Blocks Small Cell Lung Cancer Growth In vitro and In vivo OE Pardo, J Latigo, RE Jeffery, E Nye, R Poulsom, B Spencer-Dene, ... Cancer research 69 (22), 8645-8651, 2009 | 200 | 2009 |
Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells OE Pardo, A Lesay, A Arcaro, R Lopes, BL Ng, PH Warne, IA McNeish, ... Molecular and cellular biology, 2003 | 156 | 2003 |
Potent inhibition of small-cell lung cancer cell growth by simvastatin reveals selective functions of Ras isoforms in growth factor signalling UK Khanzada, OE Pardo, C Meier, J Downward, MJ Seckl, A Arcaro Oncogene 25 (6), 877-887, 2006 | 151 | 2006 |
The p90 RSK family members: common functions and isoform specificity R Lara, MJ Seckl, OE Pardo Cancer research 73 (17), 5301-5308, 2013 | 128 | 2013 |
miR‐515‐5p controls cancer cell migration through MARK 4 regulation OE Pardo, L Castellano, CE Munro, Y Hu, F Mauri, J Krell, R Lara, ... EMBO reports 17 (4), 570-584, 2016 | 114 | 2016 |
Tumor suppressor PDCD4 represses internal ribosome entry site-mediated translation of antiapoptotic proteins and is regulated by S6 kinase 2 U Liwak, N Thakor, LE Jordan, R Roy, SM Lewis, OE Pardo, M Seckl, ... Molecular and cellular biology 32 (10), 1818-1829, 2012 | 110 | 2012 |
An siRNA screen identifies RSK1 as a key modulator of lung cancer metastasis R Lara, FA Mauri, H Taylor, R Derua, A Shia, C Gray, A Nicols, RJ Shiner, ... Oncogene 30 (32), 3513-3521, 2011 | 109 | 2011 |
AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001 M Marinov, A Ziogas, OE Pardo, LT Tan, T Dhillon, FA Mauri, HA Lane, ... Clinical cancer research 15 (4), 1277-1287, 2009 | 109 | 2009 |
Phosphoinositide 3-kinase C2β regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms RM Katso, OE Pardo, A Palamidessi, CM Franz, M Marinov, ... Molecular biology of the cell 17 (9), 3729-3744, 2006 | 108 | 2006 |
hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling R Roy, D Durie, H Li, BQ Liu, JM Skehel, F Mauri, LV Cuorvo, ... Nucleic acids research 42 (20), 12483-12497, 2014 | 102 | 2014 |
Emerging roles of hnRNPA1 in modulating malignant transformation R Roy, Y Huang, MJ Seckl, OE Pardo Wiley Interdisciplinary Reviews: RNA 8 (6), e1431, 2017 | 97 | 2017 |
Novel cross talk between MEK and S6K2 in FGF-2 induced proliferation of SCLC cells OE Pardo, A Arcaro, G Salerno, TD Tetley, T Valovka, I Gout, MJ Seckl Oncogene 20 (52), 7658-7667, 2001 | 92 | 2001 |
Synthesis and anticancer activity of nordihydroguaiaretic acid (NDGA) and analogues RW McDonald, W Bunjobpon, T Liu, S Fessler, OE Pardo, IKA Freer, ... Anti-cancer drug design 16 (6), 261-270, 2001 | 77 | 2001 |
S6K2: the neglected S6 kinase family member OE Pardo, MJ Seckl Frontiers in oncology 3, 191, 2013 | 71 | 2013 |