Epigenetic gene silencing in cancer–a mechanism for early oncogenic pathway addiction? SB Baylin, JE Ohm Nature Reviews Cancer 6 (2), 107-116, 2006 | 2117 | 2006 |
A stem cell–like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing JE Ohm, KM McGarvey, X Yu, L Cheng, KE Schuebel, L Cope, ... Nature genetics 39 (2), 237-242, 2007 | 1252 | 2007 |
VEGF inhibits T-cell development and may contribute to tumor-induced immune suppression JE Ohm, DI Gabrilovich, GD Sempowski, E Kisseleva, KS Parman, ... Blood 101 (12), 4878-4886, 2003 | 616 | 2003 |
Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes P Mali, BK Chou, J Yen, Z Ye, J Zou, S Dowey, RA Brodsky, JE Ohm, ... Stem cells 28 (4), 713-720, 2010 | 569 | 2010 |
Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function DI Gabrilovich, T Ishida, S Nadaf, JE Ohm, DP Carbone Clinical cancer research 5 (10), 2963-2970, 1999 | 554 | 1999 |
Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer J Amann, S Kalyankrishna, PP Massion, JE Ohm, L Girard, H Shigematsu, ... Cancer research 65 (1), 226-235, 2005 | 527 | 2005 |
Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation K Pruitt, RL Zinn, JE Ohm, KM McGarvey, SHL Kang, DN Watkins, ... PLoS genetics 2 (3), e40, 2006 | 496 | 2006 |
VEGF as a mediator of tumor-associated immunodeficiency JE Ohm, DP Carbone Immunologic research 23, 263-272, 2001 | 495 | 2001 |
Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation MM Dikov, JE Ohm, N Ray, EE Tchekneva, J Burlison, D Moghanaki, ... The Journal of Immunology 174 (1), 215-222, 2005 | 291 | 2005 |
A DNA hypermethylation module for the stem/progenitor cell signature of cancer H Easwaran, SE Johnstone, L Van Neste, J Ohm, T Mosbruger, Q Wang, ... Genome research 22 (5), 837-849, 2012 | 290 | 2012 |
PcG proteins, DNA methylation, and gene repression by chromatin looping VK Tiwari, KM McGarvey, JDF Licchesi, JE Ohm, JG Herman, ... PLoS biology 6 (12), e306, 2008 | 232 | 2008 |
The EPIIC hypothesis: intrapartum effects on the neonatal epigenome and consequent health outcomes HG Dahlen, HP Kennedy, CM Anderson, AF Bell, A Clark, M Foureur, ... Medical hypotheses 80 (5), 656-662, 2013 | 184 | 2013 |
Abnormal DNA Methylation of CD133 in Colorectal and Glioblastoma Tumors JM Yi, HC Tsai, SC Glöckner, S Lin, JE Ohm, H Easwaran, CD James, ... Cancer research 68 (19), 8094-8103, 2008 | 175 | 2008 |
A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations VK Tiwari, L Cope, KM McGarvey, JE Ohm, SB Baylin Genome research 18 (7), 1171-1179, 2008 | 147 | 2008 |
Effect of vascular endothelial growth factor and FLT3 ligand on dendritic cell generation in vivo JE Ohm, MR Shurin, C Esche, MT Lotze, DP Carbone, DI Gabrilovich The Journal of Immunology 163 (6), 3260-3268, 1999 | 140 | 1999 |
Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines Y Adachi, CT Lee, K Coffee, N Yamagata, JE Ohm, KH Park, MM Dikov, ... Gastroenterology 123 (4), 1191-1204, 2002 | 134 | 2002 |
Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells KM McGarvey, L Van Neste, L Cope, JE Ohm, JG Herman, ... Cancer research 68 (14), 5753-5759, 2008 | 133 | 2008 |
Stem cell chromatin patterns: an instructive mechanism for DNA hypermethylation? JE Ohm, SB Baylin Cell cycle 6 (9), 1040-1043, 2007 | 118 | 2007 |
Immune dysfunction in cancer patients. JE Ohm, DP Carbone Oncology (Williston Park, NY) 16 (1 Suppl 1), 11-18, 2002 | 100 | 2002 |
Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells JE Ohm, P Mali, L Van Neste, DM Berman, L Liang, K Pandiyan, ... Cancer research 70 (19), 7662-7673, 2010 | 99 | 2010 |