| Cholinergic differentiation of human neuroblastoma SH-SY5Y cell line and its potential use as an in vitro model for Alzheimer’s disease studies LM de Medeiros, MA De Bastiani, EP Rico, P Schonhofen, B Pfaffenseller, ... Molecular Neurobiology 56, 7355-7367, 2019 | 165 | 2019 |
| Galantamine inhibits β-amyloid aggregation and cytotoxicity B Matharu, G Gibson, R Parsons, TN Huckerby, SA Moore, LJ Cooper, ... Journal of the neurological sciences 280 (1-2), 49-58, 2009 | 121 | 2009 |
| High expression of nicotinamide N-methyltransferase in patients with idiopathic Parkinson's disease RB Parsons, SW Smith, RH Waring, AC Williams, DB Ramsden Neuroscience letters 342 (1-2), 13-16, 2003 | 113 | 2003 |
| In vitro effect of the cysteine metabolites homocysteic acid, homocysteine and cysteic acid upon human neuronal cell lines. RB Parsons, RH Waring, DB Ramsden, AC Williams Neurotoxicology 19 (4-5), 599-603, 1998 | 107 | 1998 |
| Expression of nicotinamide N-methyltransferase (EC 2.1. 1.1) in the Parkinsonian brain RB Parsons, ML Smith, AC Williams, RH Waring, DB Ramsden Journal of Neuropathology & Experimental Neurology 61 (2), 111-124, 2002 | 106 | 2002 |
| A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration DA Solomon, A Stepto, WH Au, Y Adachi, DC Diaper, R Hall, A Rekhi, ... Brain 141 (10), 2908-2924, 2018 | 95 | 2018 |
| The expression of nicotinamide N-methyltransferase increases ATP synthesis and protects SH-SY5Y neuroblastoma cells against the toxicity of Complex I inhibitors RB Parsons, S Aravindan, A Kadampeswaran, EA Evans, KK Sandhu, ... Biochemical Journal 436 (1), 145-155, 2011 | 92 | 2011 |
| The aetiology of idiopathic Parkinson's disease DB Ramsden, RB Parsons, SL Ho, RH Waring Molecular Pathology 54 (6), 369, 2001 | 81 | 2001 |
| Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila DM Humphrey, RB Parsons, ZN Ludlow, T Riemensperger, G Esposito, ... Human molecular genetics 21 (12), 2698-2712, 2012 | 70 | 2012 |
| A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase MJ Van Haren, J Sastre Toraño, D Sartini, M Emanuelli, RB Parsons, ... Biochemistry 55 (37), 5307-5315, 2016 | 64 | 2016 |
| Statins inhibit the dimerization of β-secretase via both isoprenoid-and cholesterol-mediated mechanisms RB Parsons, GC Price, JK Farrant, D Subramaniam, J Adeagbo-Sheikh, ... Biochemical Journal 399 (2), 205-214, 2006 | 63 | 2006 |
| RA differentiation enhances dopaminergic features, changes redox parameters, and increases dopamine transporter dependency in 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y … FM Lopes, LL da Motta, MA De Bastiani, B Pfaffenseller, BW Aguiar, ... Neurotoxicity research 31, 545-559, 2017 | 59 | 2017 |
| Nicotinamide N-methyltransferase expression in SH-SY5Y neuroblastoma and N27 mesencephalic neurones induces changes in cell morphology via ephrin-B2 and Akt signalling MG Thomas, M Saldanha, RJ Mistry, DT Dexter, DB Ramsden, ... Cell death & disease 4 (6), e669-e669, 2013 | 57 | 2013 |
| Inhibitors of nicotinamide N-methyltransferase designed to mimic the methylation reaction transition state MJ Van Haren, R Taig, J Kuppens, JS Toraño, EE Moret, RB Parsons, ... Organic & biomolecular chemistry 15 (31), 6656-6667, 2017 | 52 | 2017 |
| Cannabinoid-based therapies and brain development: potential harmful effect of early modulation of the endocannabinoid system P Schonhofen, IJ Bristot, JA Crippa, JEC Hallak, AW Zuardi, RB Parsons, ... CNS drugs 32 (8), 697-712, 2018 | 51 | 2018 |
| Mimicking Parkinson’s disease in a dish: merits and pitfalls of the most commonly used dopaminergic in vitro models FM Lopes, IJ Bristot, LL Da Motta, RB Parsons, F Klamt NeuroMolecular Medicine 19, 241-255, 2017 | 49 | 2017 |
| The effect of foetal bovine serum supplementation upon the lactate dehydrogenase cytotoxicity assay: Important considerations for in vitro toxicity analysis MG Thomas, RM Marwood, AE Parsons, RB Parsons Toxicology in vitro 30 (1), 300-308, 2015 | 47 | 2015 |
| Cannabidiol exposure during neuronal differentiation sensitizes cells against redox-active neurotoxins P Schönhofen, LM de Medeiros, IJ Bristot, FM Lopes, MA De Bastiani, ... Molecular neurobiology 52, 26-37, 2015 | 46 | 2015 |
| Human brain cytochrome P450 1B1: immunohistochemical localization in human temporal lobe and induction by dimethylbenz (a) anthracene in astrocytoma cell line (MOG-G-CCM) CRM Rieder, RB Parsons, NJS Fitch, AC Williams, DB Ramsden Neuroscience letters 278 (3), 177-180, 2000 | 46 | 2000 |
| Potent Inhibition of Nicotinamide N-Methyltransferase by Alkene-Linked Bisubstrate Mimics Bearing Electron Deficient Aromatics Y Gao, MJ Van Haren, N Buijs, P Innocenti, Y Zhang, D Sartini, ... Journal of Medicinal Chemistry 64 (17), 12938-12963, 2021 | 43 | 2021 |
