| Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating … P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ... Archives of toxicology 87, 1315-1530, 2013 | 1404 | 2013 |
| A strategy for structuring and reporting a read-across prediction of toxicity TW Schultz, P Amcoff, E Berggren, F Gautier, M Klaric, DJ Knight, ... Regulatory Toxicology and Pharmacology 72 (3), 586-601, 2015 | 1030 | 2015 |
| Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010 S Adler, D Basketter, S Creton, O Pelkonen, J Van Benthem, V Zuang, ... Archives of toxicology 85, 367-485, 2011 | 637 | 2011 |
| Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration S Hoehme, M Brulport, A Bauer, E Bedawy, W Schormann, M Hermes, ... Proceedings of the National Academy of Sciences 107 (23), 10371-10376, 2010 | 406 | 2010 |
| High incidence of spontaneous and chemically induced liver tumors in mice deficient for connexin32 A Temme, A Buchmann, HD Gabriel, E Nelles, M Schwarz, K Willecke Current Biology 7 (9), 713-716, 1997 | 349 | 1997 |
| Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of Toxicology 91, 3477-3505, 2017 | 334 | 2017 |
| Diethylnitrosamine (DEN)-induced carcinogenic liver injury in mice R Tolba, T Kraus, C Liedtke, M Schwarz, R Weiskirchen Laboratory animals 49 (1_suppl), 59-69, 2015 | 289 | 2015 |
| A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice O Moennikes, S Loeppen, A Buchmann, P Andersson, C Ittrich, ... Cancer research 64 (14), 4707-4710, 2004 | 274 | 2004 |
| Differential gene expression in periportal and perivenous mouse hepatocytes A Braeuning, C Ittrich, C Köhle, S Hailfinger, M Bonin, A Buchmann, ... The FEBS journal 273 (22), 5051-5061, 2006 | 272 | 2006 |
| A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing D Basketter, H Clewell, I Kimber, A Rossi, B Blaauboer, R Burrier, ... | 253 | 2012 |
| Carcinogen-specific Mutational Pattern in the p53 Gene in Ultraviolet B Radiation-induced Squamous Cell Carcinomas of Mouse Skin S Kress, C Sutter, PT Strickland, H Mukhtar, J Schweizer, M Schwarz Cancer research 52 (22), 6400-6403, 1992 | 222 | 1992 |
| Inhibition of apoptosis during 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-mediated tumour promotion in rat liver S Stinchcombe, A Buchmann, KW Bock, M Schwarz Carcinogenesis 16 (6), 1271-1275, 1995 | 211 | 1995 |
| Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis. A Buchmann, R Bauer-Hofmann, J Mahr, NR Drinkwater, A Luz, ... Proceedings of the National Academy of Sciences 88 (3), 911-915, 1991 | 199 | 1991 |
| Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of β-catenin-mutated mouse liver tumors H Aydinlik, TD Nguyen, O Moennikes, A Buchmann, M Schwarz Oncogene 20 (53), 7812-7816, 2001 | 191 | 2001 |
| Consensus report on the future of animal-free systemic toxicity testing M Leist, N Hasiwa, C Rovida, M Daneshian, D Basketter, I Kimber, ... | 181 | 2014 |
| Zonal gene expression in murine liver: lessons from tumors S Hailfinger, M Jaworski, A Braeuning, A Buchmann, M Schwarz Hepatology 43 (3), 407-414, 2006 | 179 | 2006 |
| A Review of the Implementation of the Embryonic Stem Cell Test (EST) The report and recommendations of an ECVAM/ReProTect Workshop P Marx-Stoelting, E Adriaens, HJ Ahr, S Bremer, B Garthoff, HP Gelbke, ... Alternatives to Laboratory Animals 37 (3), 313-328, 2009 | 177 | 2009 |
| T‐cell factor 4 and β‐catenin chromatin occupancies pattern zonal liver metabolism in mice A Gougelet, C Torre, P Veber, C Sartor, L Bachelot, PD Denechaud, ... Hepatology 59 (6), 2344-2357, 2014 | 174 | 2014 |
| Regulation and expression of four cytochrome P-450 isoenzymes, NADPH-cytochrome P-450 reductase, the glutathione transferases B and C and microsomal epoxide hydrolase in … A Buchmann, W Kuhlmann, M Schwarz, W Kunz, CR Wolf, E Moll, ... Carcinogenesis 6 (4), 513-521, 1985 | 162 | 1985 |
| Aryl hydrocarbon receptor inhibition downregulates the TGF-β/Smad pathway in human glioblastoma cells D Gramatzki, G Pantazis, J Schittenhelm, G Tabatabai, C Köhle, W Wick, ... Oncogene 28 (28), 2593-2605, 2009 | 161 | 2009 |
