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J. Wade Davis, PhD
J. Wade Davis, PhD
Vice President of Computational Science and Head of Digital Research, Moderna
在 modernatx.com 的电子邮件经过验证
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引用次数
引用次数
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A cross-population atlas of genetic associations for 220 human phenotypes
S Sakaue, M Kanai, Y Tanigawa, J Karjalainen, M Kurki, S Koshiba, ...
Nature genetics 53 (10), 1415-1424, 2021
7912021
Genetics of 35 blood and urine biomarkers in the UK Biobank
N Sinnott-Armstrong, Y Tanigawa, D Amar, N Mars, C Benner, M Aguirre, ...
Nature genetics 53 (2), 185-194, 2021
4982021
Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval
EA King, JW Davis, JF Degner
PLoS genetics 15 (12), e1008489, 2019
4782019
Ultradeep bisulfite sequencing analysis of DNA methylation patterns in multiple gene promoters by 454 sequencing
KH Taylor, RS Kramer, JW Davis, J Guo, DJ Duff, D Xu, CW Caldwell, ...
Cancer research 67 (18), 8511-8518, 2007
3272007
Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers
N Mars, JT Koskela, P Ripatti, TTJ Kiiskinen, AS Havulinna, JV Lindbohm, ...
Nature medicine 26 (4), 549-557, 2020
3262020
Effects of vendor and genetic background on the composition of the fecal microbiota of inbred mice
AC Ericsson, JW Davis, W Spollen, N Bivens, S Givan, CE Hagan, ...
PloS one 10 (2), e0116704, 2015
3262015
Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank
JD Szustakowski, S Balasubramanian, E Kvikstad, S Khalid, PG Bronson, ...
Nature Genetics 53 (7), 942-948, 2021
2912021
Rare variant contribution to human disease in 281,104 UK Biobank exomes
Q Wang, RS Dhindsa, K Carss, AR Harper, A Nag, I Tachmazidou, ...
Nature 597 (7877), 527-532, 2021
2652021
Estrogen and androgen receptor activities of hydraulic fracturing chemicals and surface and ground water in a drilling-dense region
CD Kassotis, DE Tillitt, JW Davis, AM Hormann, SC Nagel
Endocrinology 155 (3), 897-907, 2014
2342014
Large-scale CpG methylation analysis identifies novel candidate genes and reveals methylation hotspots in acute lymphoblastic leukemia
KH Taylor, KE Pena-Hernandez, JW Davis, GL Arthur, DJ Duff, H Shi, ...
Cancer research 67 (6), 2617-2625, 2007
1742007
Genetic architecture of human plasma lipidome and its link to cardiovascular disease
R Tabassum, JT Rämö, P Ripatti, JT Koskela, M Kurki, J Karjalainen, ...
Nature communications 10 (1), 4329, 2019
1422019
Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection
Nature Medicine 27, 1012–1024, 2021
1252021
Sleep apnoea is a risk factor for severe COVID-19
S Strausz, T Kiiskinen, M Broberg, S Ruotsalainen, J Koskela, A Bachour, ...
Bmj open respiratory research 8 (1), e000845, 2021
1172021
Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes
KJ Karczewski, M Solomonson, KR Chao, JK Goodrich, G Tiao, W Lu, ...
Cell Genomics 2 (9), 2022
1082022
Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic health
S Strausz, S Ruotsalainen, HM Ollila, J Karjalainen, T Kiiskinen, M Reeve, ...
European Respiratory Journal 57 (5), 2021
1082021
The role of polygenic risk and susceptibility genes in breast cancer over the course of life
N Mars, E Widén, S Kerminen, T Meretoja, M Pirinen, ...
Nature communications 11 (1), 6383, 2020
1072020
The citrus flavonoids hesperetin and nobiletin differentially regulate low density lipoprotein receptor gene transcription in HepG2 liver cells
B Morin, LNA Nichols, KM Zalasky, JW Davis, JA Manthey, LJ Holland
The Journal of nutrition 138 (7), 1274-1281, 2008
1072008
Differential DNA methylation patterns of small B-cell lymphoma subclasses with different clinical behavior
FB Rahmatpanah, S Carstens, J Guo, O Sjahputera, KH Taylor, D Duff, ...
Leukemia 20 (10), 1855-1862, 2006
1032006
Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan
S Sakaue, M Kanai, J Karjalainen, M Akiyama, M Kurki, N Matoba, ...
Nature medicine 26 (4), 542-548, 2020
932020
Genetic associations of protein-coding variants in human disease
BB Sun, MI Kurki, CN Foley, A Mechakra, CY Chen, E Marshall, JB Wilk, ...
Nature 603 (7899), 95-102, 2022
882022
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