Antibiofilm activity of host defence peptides: Complexity provides opportunities REW Hancock, MA Alford, EF Haney Nature Reviews Microbiology 19 (12), 786-797, 2021 | 154 | 2021 |
Cathelicidin host defense peptides and inflammatory signaling: Striking a balance MA Alford, B Baquir, FL Santana, EF Haney, REW Hancock Frontiers in microbiology 11, 547718, 2020 | 75 | 2020 |
Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on ESKAPE Bacterial Pathogens JE Nielsen, MA Alford, DBY Yung, N Molchanova, JA Fortkort, JS Lin, ... ACS infectious diseases 8 (3), 533-545, 2022 | 45 | 2022 |
Multifunctional antibiotic–host defense peptide conjugate kills bacteria, eradicates biofilms, and modulates the innate immune response H Etayash, M Alford, N Akhoundsadegh, M Drayton, SK Straus, ... Journal of Medicinal Chemistry 64 (22), 16854-16863, 2021 | 22 | 2021 |
NtrBC regulates invasiveness and virulence of Pseudomonas aeruginosa during high-density infection MA Alford, A Baghela, ATY Yeung, D Pletzer, REW Hancock Frontiers in microbiology 11, 533374, 2020 | 22 | 2020 |
Enzymatically releasable polyethylene glycol–host defense peptide conjugates with improved activity and biocompatibility M Drayton, MA Alford, D Pletzer, EF Haney, Y Machado, HD Luo, ... Journal of Controlled Release 339, 220-231, 2021 | 11 | 2021 |
Murine model of sinusitis infection for screening antimicrobial and immunomodulatory therapies MA Alford, KYG Choi, MJ Trimble, H Masoudi, P Kalsi, D Pletzer, ... Frontiers in Cellular and Infection Microbiology 11, 621081, 2021 | 10 | 2021 |
Dismantling the bacterial virulence program MA Alford, D Pletzer, REW Hancock Microbial Biotechnology 12 (3), 409-413, 2019 | 10 | 2019 |
Competition between Pseudomonas aeruginosa and Staphylococcus aureus is dependent on intercellular signaling and regulated by the NtrBC two-component … MA Alford, S Mann, N Akhoundsadegh, REW Hancock Scientific Reports 12 (1), 9027, 2022 | 9 | 2022 |
The ColR/S two-component system is a conserved determinant of host association across Pseudomonas species CL Wiessman, Y Zhang, MA Alford, CD Hamilton, M Dosanjh, D Thoms, ... ISME J., Online ahead of print., 2022 | 8 | 2022 |
Peptide 1018 inhibits swarming and influences Anr-regulated gene expression downstream of the stringent stress response in Pseudomonas aeruginosa LV Wilkinson, MA Alford, SR Coleman, BC Wu, AHY Lee, TM Blimkie, ... PloS one 16 (4), e0250977, 2021 | 5 | 2021 |
Characterization of novel kainic acid analogs as inhibitors of select microglial functions MA Alford, Z Tian, F Menard, A Klegeris European Journal of Pharmacology 851, 25-35, 2019 | 5 | 2019 |
Antimicrobial susceptibility testing of invasive isolates of Streptococcus pneumoniae from Canadian patients: the SAVE study, 2011–2020 MA Alford, JA Karlowsky, HJ Adam, MR Baxter, J Schellenberg, ... Journal of Antimicrobial Chemotherapy 78 (Supplement_1), i8-i16, 2023 | 4 | 2023 |
Novel Alligator Cathelicidin As-CATH8 Demonstrates Anti-Infective Activity against Clinically Relevant and Crocodylian Bacterial Pathogens FL Santana, K Estrada, MA Alford, BC Wu, M Dostert, L Pedraz, ... Antibiotics 11 (11), 1603, 2022 | 4 | 2022 |
NtrBC Selectively Regulates Host-Pathogen Interactions, Virulence, and Ciprofloxacin Susceptibility of Pseudomonas aeruginosa MA Alford, B Baquir, A An, KYG Choi, REW Hancock Frontiers in Cellular and Infection Microbiology 11, 694789, 2021 | 4 | 2021 |
Intracellular Pseudomonas aeruginosa persist and evade antibiotic treatment in a wound infection model S Pont, F Nilly, L Berry, A Bonhoure, MA Alford, M Louis, P Nogaret, ... bioRxiv, 2024.05. 15.594279, 2024 | | 2024 |
BosR: A novel biofilm-specific regulator in Pseudomonas aeruginosa M Dostert, CR Belanger, L Pedraz, MA Alford, TM Blimkie, RF Falsafi, ... Frontiers in Microbiology 13, 1021021, 2022 | | 2022 |