Critical enzyme reactions in aromatic catabolism for microbial lignin conversion E Erickson, A Bleem, E Kuatsjah, AZ Werner, JL DuBois, JE McGeehan, ... Nature Catalysis 5 (2), 86-98, 2022 | 69 | 2022 |
Protein engineering reveals mechanisms of functional amyloid formation in Pseudomonas aeruginosa biofilms A Bleem, G Christiansen, DJ Madsen, H Maric, K Strømgaard, JD Bryers, ... Journal of molecular biology 430 (20), 3751-3763, 2018 | 50 | 2018 |
Designed α-sheet peptides suppress amyloid formation in Staphylococcus aureus biofilms A Bleem, R Francisco, JD Bryers, V Daggett npj Biofilms and Microbiomes 3 (1), 16, 2017 | 49 | 2017 |
Structural and functional diversity among amyloid proteins: agents of disease, building blocks of biology, and implications for molecular engineering A Bleem, V Daggett Biotechnology and Bioengineering 114 (1), 7-20, 2017 | 38 | 2017 |
Chemical and Physical Variability in Structural Isomers of an l/d α-Sheet Peptide Designed To Inhibit Amyloidogenesis NL Maris, D Shea, A Bleem, JD Bryers, V Daggett Biochemistry 57 (5), 507-510, 2018 | 33 | 2018 |
Engineering a cytochrome P450 for demethylation of lignin-derived aromatic aldehydes ES Ellis, DJ Hinchen, A Bleem, L Bu, SJB Mallinson, MD Allen, BR Streit, ... JACS Au 1 (3), 252-261, 2021 | 27 | 2021 |
Discovery, characterization, and metabolic engineering of Rieske non-heme iron monooxygenases for guaiacol O-demethylation A Bleem, E Kuatsjah, GN Presley, DJ Hinchen, M Zahn, DC Garcia, ... Chem Catalysis 2 (8), 1989-2011, 2022 | 13 | 2022 |
RB-TnSeq identifies genetic targets for improved tolerance of Pseudomonas putida towards compounds relevant to lignin conversion AJ Borchert, A Bleem, GT Beckham Metabolic Engineering 77, 208-218, 2023 | 11 | 2023 |
Multiplexed fitness profiling by RB-TnSeq elucidates pathways for lignin-related aromatic catabolism in Sphingobium sp. SYK-6 A Bleem, R Kato, ZA Kellermyer, R Katahira, M Miyamoto, K Niinuma, ... Cell Reports 42 (8), 2023 | 10 | 2023 |
Catalytic carbon–carbon bond cleavage in lignin via manganese–zirconium-mediated autoxidation CT Palumbo, NX Gu, AC Bleem, KP Sullivan, R Katahira, LM Stanley, ... Nature Communications 15 (1), 862, 2024 | 7 | 2024 |
Experimental and analytical approaches for improving the resolution of randomly barcoded transposon insertion sequencing (RB-TnSeq) studies AJ Borchert, A Bleem, GT Beckham ACS Synthetic Biology 11 (6), 2015-2021, 2022 | 7 | 2022 |
Autoxidation catalysis for carbon–carbon bond cleavage in lignin NX Gu, CT Palumbo, AC Bleem, KP Sullivan, SJ Haugen, SP Woodworth, ... ACS Central Science 9 (12), 2277-2285, 2023 | 5 | 2023 |
Designed α-sheet peptides disrupt uropathogenic E. coli biofilms rendering bacteria susceptible to antibiotics and immune cells A Bleem, T Prosswimmer, R Chen, TF Hady, J Li, JD Bryers, V Daggett Scientific Reports 13 (1), 9272, 2023 | 5 | 2023 |
Environment constrains fitness advantages of division of labor in microbial consortia engineered for metabolite push or pull interactions AE Beck, K Pintar, D Schepens, A Schrammeck, T Johnson, A Bleem, ... Msystems 7 (4), e00051-22, 2022 | 5 | 2022 |
The catabolism of lignin-derived p-methoxylated aromatic compounds by Rhodococcus jostii RHA1 ME Wolf, AT Lalande, BL Newman, AC Bleem, CT Palumbo, GT Beckham, ... Applied and Environmental Microbiology 90 (3), e02155-23, 2024 | 1 | 2024 |
Machine learning analysis of RB-TnSeq fitness data predicts functional gene modules in Pseudomonas putida KT2440 AJ Borchert, AC Bleem, HG Lim, K Rychel, KD Dooley, ZA Kellermyer, ... Msystems 9 (3), e00942-23, 2024 | 1 | 2024 |
Reagents and methods for treating bacterial infection V Daggett, A Bleem US Patent 11,033,604, 2021 | 1 | 2021 |
Evolution and engineering of pathways for aromatic O-demethylation in Pseudomonas putida KT2440 AC Bleem, E Kuatsjah, J Johnsen, ET Mohamed, WG Alexander, ... Metabolic Engineering 84, 145-157, 2024 | | 2024 |
Biophysical strategies to inhibit bacterial amyloid formation and undermine biofilm infections A Bleem | | 2019 |