| Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin–induced intestinal fluid secretion T Ma, JR Thiagarajah, H Yang, ND Sonawane, C Folli, LJV Galietta, ... The Journal of clinical investigation 110 (11), 1651-1658, 2002 | 822 | 2002 |
| Role of airway surface liquid and submucosal glands in cystic fibrosis lung disease AS Verkman, Y Song, JR Thiagarajah American Journal of Physiology-Cell Physiology 284 (1), C2-C15, 2003 | 327 | 2003 |
| Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway CL Evavold, I Hafner-Bratkovič, P Devant, JM D’Andrea, EM Ngwa, ... Cell 184 (17), 4495-4511. e19, 2021 | 261 | 2021 |
| Inhibition of Ca2+-activated Cl− channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea W Namkung, JR Thiagarajah, PW Phuan, AS Verkman The FASEB Journal 24 (11), 4178, 2010 | 239 | 2010 |
| Secretory diarrhoea: mechanisms and emerging therapies JR Thiagarajah, M Donowitz, AS Verkman Nature reviews Gastroenterology & hepatology 12 (8), 446-457, 2015 | 213 | 2015 |
| Chloride concentration in endosomes measured using a ratioable fluorescent Cl− indicator: evidence for chloride accumulation during acidification ND Sonawane, JR Thiagarajah, AS Verkman Journal of Biological Chemistry 277 (7), 5506-5513, 2002 | 206 | 2002 |
| Aquaporin deletion in mice reduces corneal water permeability and delays restoration of transparency after swelling JR Thiagarajah, AS Verkman Journal of Biological Chemistry 277 (21), 19139-19144, 2002 | 185 | 2002 |
| Advances in evaluation of chronic diarrhea in infants JR Thiagarajah, DS Kamin, S Acra, JD Goldsmith, JT Roland, WI Lencer, ... Gastroenterology 154 (8), 2045-2059. e6, 2018 | 178 | 2018 |
| Prevention of toxin-induced intestinal ion and fluid secretion by a small-molecule CFTR inhibitor JR Thiagarajah, T Broadbent, E Hsieh, AS Verkman Gastroenterology 126 (2), 511-519, 2004 | 173 | 2004 |
| A small molecule CFTR inhibitor produces cystic fibrosis‐like submucosal gland fluid secretions in normal airways JR Thiagarajah, Y Song, PM Haggie, AS Verkman The FASEB journal 18 (7), 875-877, 2004 | 142 | 2004 |
| CFTR pharmacology and its role in intestinal fluid secretion JR Thiagarajah, AS Verkman Current opinion in pharmacology 3 (6), 594-599, 2003 | 140 | 2003 |
| Impaired enterocyte proliferation in aquaporin-3 deficiency in mouse models of colitis JR Thiagarajah, D Zhao, AS Verkman Gut 56 (11), 1529-1535, 2007 | 125 | 2007 |
| New drug targets for cholera therapy JR Thiagarajah, AS Verkman Trends in Pharmacological Sciences 26 (4), 172-175, 2005 | 102 | 2005 |
| Aquaporin-3 mediates hydrogen peroxide-dependent responses to environmental stress in colonic epithelia JR Thiagarajah, J Chang, JA Goettel, AS Verkman, WI Lencer Proceedings of the National Academy of Sciences 114 (3), 568-573, 2017 | 99 | 2017 |
| Noninvasive early detection of brain edema in mice by near‐infrared light scattering JR Thiagarajah, MC Papadopoulos, AS Verkman Journal of neuroscience research 80 (2), 293-299, 2005 | 93 | 2005 |
| Submucosal gland dysfunction as a primary defect in cystic fibrosis D Salinas, PM Haggie, JR Thiagarajah, Y Song, K Rosbe, WE Finkbeiner, ... The FASEB journal 19 (3), 1-13, 2005 | 89 | 2005 |
| Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal mice EA Ko, BJ Jin, W Namkung, T Ma, JR Thiagarajah, AS Verkman Gut 63 (7), 1120-1129, 2014 | 82 | 2014 |
| CFTR inhibitors for treating diarrheal disease JR Thiagarajah, AS Verkman Clinical Pharmacology & Therapeutics 92 (3), 287-290, 2012 | 80 | 2012 |
| CFTR activator increases intestinal fluid secretion and normalizes stool output in a mouse model of constipation O Cil, PW Phuan, S Lee, J Tan, PM Haggie, MH Levin, L Sun, ... Cellular and molecular gastroenterology and hepatology 2 (3), 317-327, 2016 | 78 | 2016 |
| Sodium and chloride concentrations, pH, and depth of airway surface liquid in distal airways Y Song, J Thiagarajah, AS Verkman The Journal of general physiology 122 (5), 511-519, 2003 | 78 | 2003 |
