| DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae JF Heidelberg, JA Eisen, WC Nelson, RA Clayton, ML Gwinn, RJ Dodson, ... Nature 406 (6795), 477-483, 2000 | 2198 | 2000 |
| Complete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58 H Tettelin, NJ Saunders, J Heidelberg, AC Jeffries, KE Nelson, JA Eisen, ... Science 287 (5459), 1809-1815, 2000 | 1404 | 2000 |
| CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy TJ Fry, NN Shah, RJ Orentas, M Stetler-Stevenson, CM Yuan, ... Nature medicine 24 (1), 20-28, 2018 | 1272 | 2018 |
| Genome Sequence of the Radioresistant Bacterium Deinococcus radiodurans R1 O White, JA Eisen, JF Heidelberg, EK Hickey, JD Peterson, RJ Dodson, ... Science 286 (5444), 1571-1577, 1999 | 1209 | 1999 |
| CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity E Jacoby, SM Nguyen, TJ Fountaine, K Welp, B Gryder, H Qin, Y Yang, ... Nature communications 7 (1), 12320, 2016 | 411 | 2016 |
| CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial JY Spiegel, S Patel, L Muffly, NM Hossain, J Oak, JH Baird, MJ Frank, ... Nature medicine 27 (8), 1419-1431, 2021 | 378 | 2021 |
| Generation of clinical-grade CD19-specific CAR-modified CD8+ memory stem cells for the treatment of human B-cell malignancies M Sabatino, J Hu, M Sommariva, S Gautam, V Fellowes, JD Hocker, ... Blood, The Journal of the American Society of Hematology 128 (4), 519-528, 2016 | 370 | 2016 |
| CD4/CD8 T-cell selection affects chimeric antigen receptor (CAR) T-cell potency and toxicity: updated results from a phase I anti-CD22 CAR T-cell trial NN Shah, SL Highfill, H Shalabi, B Yates, J Jin, PL Wolters, A Ombrello, ... Journal of Clinical Oncology 38 (17), 1938-1950, 2020 | 340 | 2020 |
| High-Throughput GoMiner, an'industrial-strength'integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common … BR Zeeberg, H Qin, S Narasimhan, M Sunshine, H Cao, DW Kane, ... BMC bioinformatics 6, 1-18, 2005 | 334 | 2005 |
| Preclinical development of bivalent chimeric antigen receptors targeting both CD19 and CD22 H Qin, S Ramakrishna, S Nguyen, TJ Fountaine, A Ponduri, ... Molecular Therapy-Oncolytics 11, 127-137, 2018 | 242 | 2018 |
| TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearance Y Yang, ME Kohler, CD Chien, CT Sauter, E Jacoby, C Yan, Y Hu, ... Science translational medicine 9 (417), eaag1209, 2017 | 192 | 2017 |
| Modulation of target antigen density improves CAR T-cell functionality and persistence S Ramakrishna, SL Highfill, Z Walsh, SM Nguyen, H Lei, JF Shern, H Qin, ... Clinical Cancer Research 25 (17), 5329-5341, 2019 | 143 | 2019 |
| Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis S Kaczanowska, DW Beury, V Gopalan, AK Tycko, H Qin, ME Clements, ... Cell 184 (8), 2033-2052. e21, 2021 | 129 | 2021 |
| Murine allogeneic CD19 CAR T cells harbor potent antileukemic activity but have the potential to mediate lethal GVHD E Jacoby, Y Yang, H Qin, CD Chien, JN Kochenderfer, TJ Fry Blood, The Journal of the American Society of Hematology 127 (10), 1361-1370, 2016 | 117 | 2016 |
| Clonal expansion of CAR T cells harboring lentivector integration in the CBL gene following anti-CD22 CAR T-cell therapy NN Shah, H Qin, B Yates, L Su, H Shalabi, M Raffeld, MA Ahlman, ... Blood advances 3 (15), 2317-2322, 2019 | 101 | 2019 |
| CD19/22 CAR T cells in children and young adults with B-ALL: phase 1 results and development of a novel bicistronic CAR H Shalabi, H Qin, A Su, B Yates, PL Wolters, SM Steinberg, JA Ligon, ... Blood, The Journal of the American Society of Hematology 140 (5), 451-463, 2022 | 75 | 2022 |
| Phase 1 study of CD19/CD22 bispecific chimeric antigen receptor (CAR) therapy in children and young adults with B cell acute lymphoblastic leukemia (ALL) LM Schultz, KL Davis, C Baggott, C Chaudry, AC Marcy, S Mavroukakis, ... Blood 132, 898, 2018 | 58 | 2018 |
| Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients K Ishii, M Pouzolles, CD Chien, RA Erwin-Cohen, ME Kohler, H Qin, H Lei, ... The Journal of clinical investigation 130 (10), 5425-5443, 2020 | 50 | 2020 |
| Systematic preclinical evaluation of CD33-directed chimeric antigen receptor T cell immunotherapy for acute myeloid leukemia defines optimized construct design H Qin, L Yang, JA Chukinas, NN Shah, S Tarun, M Pouzolles, CD Chien, ... Journal for immunotherapy of cancer 9 (9), 2021 | 44 | 2021 |
| An optimized bicistronic chimeric antigen receptor against GPC2 or CD276 overcomes heterogeneous expression in neuroblastoma M Tian, AT Cheuk, JS Wei, A Abdelmaksoud, HC Chou, D Milewski, ... The Journal of Clinical Investigation 132 (16), 2022 | 39 | 2022 |
