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Mechanisms of hepatotoxicity H Jaeschke, GJ Gores, AI Cederbaum, JA Hinson, D Pessayre, ... Toxicological sciences 65 (2), 166-176, 2002 | 1805 | 2002 |
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating … P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ... Archives of toxicology 87, 1315-1530, 2013 | 1403 | 2013 |
Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning H Jaeschke American Journal of Physiology-Gastrointestinal and Liver Physiology 284 (1 …, 2003 | 1232 | 2003 |
Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver H Jaeschke, A Farhood American Journal of Physiology-Gastrointestinal and Liver Physiology 260 (3 …, 1991 | 987 | 1991 |
Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity H Jaeschke, MR McGill, A Ramachandran Drug metabolism reviews 44 (1), 88-106, 2012 | 980 | 2012 |
Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo H Jaeschke, A Farhood, CW Smith The FASEB Journal 4 (15), 3355-3359, 1990 | 936 | 1990 |
The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation MR McGill, MR Sharpe, CD Williams, M Taha, SC Curry, H Jaeschke The Journal of clinical investigation 122 (4), 1574-1583, 2012 | 846 | 2012 |
Acetaminophen hepatotoxicity AM Larson Clinics in liver disease 11 (3), 525-548, 2007 | 846* | 2007 |
Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury H Jaeschke, JJ Lemasters Gastroenterology 125 (4), 1246-1257, 2003 | 698 | 2003 |
Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis MR McGill, H Jaeschke Pharmaceutical research 30, 2174-2187, 2013 | 694 | 2013 |
Intracellular signaling mechanisms of acetaminophen-induced liver cell death H Jaeschke, ML Bajt Toxicological sciences 89 (1), 31-41, 2006 | 661 | 2006 |
Reactive oxygen and mechanisms of inflammatory liver injury: present concepts H Jaeschke Journal of gastroenterology and hepatology 26, 173-179, 2011 | 644 | 2011 |
Mechanisms of neutrophil‐induced parenchymal cell injury H Jaeschke, CW Smith Journal of leukocyte biology 61 (6), 647-653, 1997 | 601 | 1997 |
Mechanisms of Liver Injury. II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions H Jaeschke American Journal of Physiology-Gastrointestinal and Liver Physiology 290 (6 …, 2006 | 588 | 2006 |
Mitochondrial permeability transition in acetaminophen‐induced necrosis and apoptosis of cultured mouse hepatocytes K Kon, JS Kim, H Jaeschke, JJ Lemasters Hepatology 40 (5), 1170-1179, 2004 | 575 | 2004 |
The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity H Jaeschke, TR Knight, ML Bajt Toxicology letters 144 (3), 279-288, 2003 | 545 | 2003 |
Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis K Allen, H Jaeschke, BL Copple The American journal of pathology 178 (1), 175-186, 2011 | 541 | 2011 |
Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis? JS Gujral, TR Knight, A Farhood, ML Bajt, H Jaeschke Toxicological sciences 67 (2), 322-328, 2002 | 526 | 2002 |
Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity H Jaeschke, CD Williams, A Ramachandran, ML Bajt Liver International 32 (1), 8-20, 2012 | 509 | 2012 |