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Kiichi Hirota
Kiichi Hirota
Kansai Medical University
在 hirakata.kmu.ac.jp 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
PC Mahon, K Hirota, GL Semenza
Genes & development 15 (20), 2675-2686, 2001
18492001
Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and …
R Fukuda, K Hirota, F Fan, Y Do Jung, LM Ellis, GL Semenza
Journal of Biological Chemistry 277 (41), 38205-38211, 2002
10312002
AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1
K Hirota, M Matsui, S Iwata, A Nishiyama, K Mori, J Yodoi
Proceedings of the National Academy of Sciences 94 (8), 3633-3638, 1997
10261997
Identification of thioredoxin-binding protein-2/vitamin D3 up-regulated protein 1 as a negative regulator of thioredoxin function and expression
A Nishiyama, M Matsui, S Iwata, K Hirota, H Masutani, H Nakamura, ...
Journal of Biological Chemistry 274 (31), 21645-21650, 1999
8361999
Distinct roles of thioredoxin in the cytoplasm and in the nucleus: a two-step mechanism of redox regulation of transcription factor NF-κB
K Hirota, M Murata, Y Sachi, H Nakamura, J Takeuchi, K Mori, J Yodoi
Journal of Biological Chemistry 274 (39), 27891-27897, 1999
7821999
Cell type–specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia …
BD Kelly, SF Hackett, K Hirota, Y Oshima, Z Cai, S Berg-Dixon, A Rowan, ...
Circulation research 93 (11), 1074-1081, 2003
7812003
Molecular mechanisms of transcription activation by HLF and HIF1α in response to hypoxia: their stabilization and redox signal‐induced interaction with CBP/p300
M Ema, K Hirota, J Mimura, H Abe, J Yodoi, K Sogawa, L Poellinger, ...
The EMBO journal, 1999
7641999
Regulation of angiogenesis by hypoxia-inducible factor 1
K Hirota, GL Semenza
Critical reviews in oncology/hematology 59 (1), 15-26, 2006
6732006
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
SO Ang, H Chen, K Hirota, VR Gordeuk, J Jelinek, Y Guan, E Liu, ...
Nature genetics 32 (4), 614-621, 2002
6162002
Thioredoxin-dependent redox regulation of p53-mediated p21 activation
M Ueno, H Masutani, RJ Arai, A Yamauchi, K Hirota, T Sakai, T Inamoto, ...
Journal of Biological Chemistry 274 (50), 35809-35815, 1999
5321999
Nitric oxide induces hypoxia-inducible factor 1 activation that is dependent on MAPK and phosphatidylinositol 3-kinase signaling
K Kasuno, S Takabuchi, K Fukuda, S Kizaka-Kondoh, J Yodoi, T Adachi, ...
Journal of Biological Chemistry 279 (4), 2550-2558, 2004
2962004
Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases
K Hirota, GL Semenza
Biochemical and biophysical research communications 338 (1), 610-616, 2005
2862005
Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer
T Hiraga, S Kizaka-Kondoh, K Hirota, M Hiraoka, T Yoneda
Cancer research 67 (9), 4157-4163, 2007
2802007
Redox control of resistance to cis-diamminedichloroplatinum (II)(CDDP): protective effect of human thioredoxin against CDDP-induced cytotoxicity.
T Sasada, S Iwata, N Sato, Y Kitaoka, K Hirota, K Nakamura, A Nishiyama, ...
The Journal of clinical investigation 97 (10), 2268-2276, 1996
2571996
Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation
SJ Wei, A Botero, K Hirota, CM Bradbury, S Markovina, A Laszlo, DR Spitz, ...
Cancer research 60 (23), 6688-6695, 2000
2462000
Nucleoredoxin, glutaredoxin, and thioredoxin differentially regulate NF-κB, AP-1, and CREB activation in HEK293 cells
K Hirota, M Matsui, M Murata, Y Takashima, FS Cheng, T Itoh, K Fukuda, ...
Biochemical and biophysical research communications 274 (1), 177-182, 2000
2412000
Direct association with thioredoxin allows redox regulation of glucocorticoid receptor function
Y Makino, N Yoshikawa, K Okamoto, K Hirota, J Yodoi, I Makino, ...
Journal of Biological Chemistry 274 (5), 3182-3188, 1999
2401999
Rac1 activity is required for the activation of hypoxia-inducible factor 1
K Hirota, GL Semenza
Journal of Biological Chemistry 276 (24), 21166-21172, 2001
2192001
Full-length 16S rRNA gene amplicon analysis of human gut microbiota using MinION™ nanopore sequencing confers species-level resolution
Y Matsuo, S Komiya, Y Yasumizu, Y Yasuoka, K Mizushima, T Takagi, ...
BMC microbiology 21, 1-13, 2021
2152021
UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α
Y Goto, L Zeng, CJ Yeom, Y Zhu, A Morinibu, K Shinomiya, M Kobayashi, ...
Nature communications 6 (1), 6153, 2015
2132015
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