Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics U Anand, A Dey, AKS Chandel, R Sanyal, A Mishra, DK Pandey, ... Genes & Diseases 10 (4), 1367-1401, 2023 | 278 | 2023 |
E3 Ubiquitin Ligases Neurobiological Mechanisms: Development to Degeneration A Upadhyay, V Joshi, A Amanullah, R Mishra, N Arora, A Prasad, ... Frontiers in Molecular Neuroscience 10, 151, 2017 | 69 | 2017 |
A decade of boon or burden: what has the CHIP ever done for cellular protein quality control mechanism implicated in neurodegeneration and aging? V Joshi, A Amanullah, A Upadhyay, R Mishra, A Kumar, A Mishra Frontiers in molecular neuroscience 9, 93, 2016 | 67 | 2016 |
Cancer: An unknown territory; rethinking before going ahead A Upadhyay Genes & Diseases 8 (5), 655-661, 2021 | 58 | 2021 |
Polyphenolic flavonoid (Myricetin) upregulated proteasomal degradation mechanisms: Eliminates neurodegenerative proteins aggregation V Joshi, R Mishra, A Upadhyay, A Amanullah, KM Poluri, S Singh, ... Journal of cellular physiology 234 (11), 20900-20914, 2019 | 53 | 2019 |
Gp78 E3 Ubiquitin Ligase: Essential Functions and Contributions in Proteostasis V Joshi, A Upadhyay, A Kumar, A Mishra Frontiers in Cellular Neuroscience 11, 259, 2017 | 48 | 2017 |
Pulse-chase proteomics of the App knockin mouse models of Alzheimer’s disease reveals that synaptic dysfunction originates in presynaptic terminals TJ Hark, NR Rao, C Castillon, T Basta, S Smukowski, H Bao, A Upadhyay, ... Cell systems 12 (2), 141-158. e9, 2021 | 43 | 2021 |
Proteasome‐mediated proteostasis: Novel medicinal and pharmacological strategies for diseases R Mishra, A Upadhyay, VK Prajapati, A Mishra Medicinal research reviews 38 (6), 1916-1973, 2018 | 43 | 2018 |
Lanosterol Suppresses the Aggregation and Cytotoxicity of Misfolded Proteins Linked with Neurodegenerative Diseases A Upadhyay, A Amanullah, R Mishra, A Kumar, A Mishra Molecular Neurobiology, 1-14, 2017 | 43 | 2017 |
Myricetin reduces toxic level of CAG repeats RNA in Huntington’s disease (HD) and Spino cerebellar Ataxia (SCAs) E Khan, A Tawani, SK Mishra, AK Verma, A Upadhyay, M Kumar, ... ACS chemical biology 13 (1), 180-188, 2018 | 37 | 2018 |
Terpenoids as promising therapeutic molecules against Alzheimer’s disease: amyloid beta-and acetylcholinesterase-directed pharmacokinetic and molecular docking analyses M Awasthi, AK Upadhyay, S Singh, VP Pandey, UN Dwivedi Molecular Simulation 44 (1), 1-11, 2018 | 36 | 2018 |
Ubiquitin ligase ITCH recruitment suppresses the aggregation and cellular toxicity of cytoplasmic misfolded proteins D Chhangani, A Upadhyay, A Amanullah, V Joshi, A Mishra Scientific reports 4 (1), 5077, 2014 | 32 | 2014 |
Progressing neurobiological strategies against proteostasis failure: Challenges in neurodegeneration A Amanullah, A Upadhyay, V Joshi, R Mishra, NR Jana, A Mishra Progress in neurobiology 159, 1-38, 2017 | 31 | 2017 |
Mahogunin ring finger 1 suppresses misfolded polyglutamine aggregation and cytotoxicity D Chhangani, N Nukina, M Kurosawa, A Amanullah, V Joshi, A Upadhyay, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (9 …, 2014 | 31 | 2014 |
Herpesviruses and the hidden links to Multiple Sclerosis neuropathology S Jakhmola, A Upadhyay, K Jain, A Mishra, HC Jha Journal of Neuroimmunology 358, 577636, 2021 | 29 | 2021 |
Mahogunin ring finger-1 (MGRN1), a multifaceted ubiquitin ligase: recent unraveling of neurobiological mechanisms A Upadhyay, A Amanullah, D Chhangani, R Mishra, A Prasad, A Mishra Molecular neurobiology 53 (7), 4484-4496, 2016 | 29 | 2016 |
Ibuprofen induces mitochondrial-mediated apoptosis through proteasomal dysfunction A Upadhyay, A Amanullah, D Chhangani, V Joshi, R Mishra, A Mishra Molecular neurobiology 53, 6968-6981, 2016 | 27 | 2016 |
Flavonoid-Based Nanomedicines in Alzheimer’s Disease Therapeutics: Promises Made, a Long Way To Go P Prasanna, A Upadhyay ACS Pharmacology & Translational Science 4 (1), 74-95, 2021 | 25 | 2021 |
The dichotomous role of extracellular vesicles in the central nervous system DR Graykowski, YZ Wang, A Upadhyay, JN Savas Iscience 23 (9), 2020 | 24 | 2020 |
Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing A Upadhyay, A Amanullah, D Chhangani, R Mishra, A Mishra Ageing Research Reviews 24, 138-159, 2015 | 24 | 2015 |