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Peter J McKinnon
Peter J McKinnon
Professor
在 stjude.org 的电子邮件经过验证
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Puma is an essential mediator of p53-dependent and-independent apoptotic pathways
JR Jeffers, E Parganas, Y Lee, C Yang, JL Wang, J Brennan, ...
Cancer cell 4 (4), 321-328, 2003
11032003
Subtypes of medulloblastoma have distinct developmental origins
P Gibson, Y Tong, G Robinson, MC Thompson, DS Currle, C Eden, ...
Nature 468 (7327), 1095-1099, 2010
9342010
Gustducin is a taste-cell-specific G protein closely related to the transducins
SK McLaughlin, PJ McKinnon, RF Margolskee
Nature 357 (6379), 563-569, 1992
8151992
Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development
OV Lagutin, CC Zhu, D Kobayashi, J Topczewski, K Shimamura, ...
Genes & development 17 (3), 368-379, 2003
5422003
Phosphorylation of SMC1 is a critical downstream event in the ATM–NBS1–BRCA1 pathway
R Kitagawa, CJ Bakkenist, PJ McKinnon, MB Kastan
Genes & development 18 (12), 1423-1438, 2004
5392004
Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system
KH Herzog, MJ Chong, M Kapsetaki, JI Morgan, PJ McKinnon
Science 280 (5366), 1089-1091, 1998
5001998
ATM and ataxia telangiectasia: second in molecular medicine review series
PJ McKinnon
EMBO reports 5 (8), 772-776, 2004
4962004
Identification of early replicating fragile sites that contribute to genome instability
JH Barlow, RB Faryabi, E Callén, N Wong, A Malhowski, HT Chen, ...
Cell 152 (3), 620-632, 2013
4702013
The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates
I Ahel, U Rass, SF El-Khamisy, S Katyal, PM Clements, PJ McKinnon, ...
Nature 443 (7112), 713-716, 2006
4422006
Human leukocyte antigen-B-associated transcript 3 is released from tumor cells and engages the NKp30 receptor on natural killer cells
EP von Strandmann, VR Simhadri, B von Tresckow, S Sasse, KS Reiners, ...
Immunity 27 (6), 965-974, 2007
4312007
A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
M Murga, S Bunting, MF Montana, R Soria, F Mulero, M Canamero, Y Lee, ...
Nature genetics 41 (8), 891-898, 2009
4162009
Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion
M Rangachari, C Zhu, K Sakuishi, S Xiao, J Karman, A Chen, M Angin, ...
Nature medicine 18 (9), 1394-1400, 2012
3992012
DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation
D Simsek, E Brunet, SYW Wong, S Katyal, Y Gao, PJ McKinnon, J Lou, ...
PLoS genetics 7 (6), e1002080, 2011
3772011
Genome organization drives chromosome fragility
A Canela, Y Maman, S Jung, N Wong, E Callen, A Day, KR Kieffer-Kwon, ...
Cell 170 (3), 507-521. e18, 2017
3712017
DNA repair deficiency and neurological disease
PJ McKinnon
Nature Reviews Neuroscience 10 (2), 100-112, 2009
3692009
DNA strand break repair and human genetic disease
PJ McKinnon, KW Caldecott
Annu. Rev. Genomics Hum. Genet. 8, 37-55, 2007
3672007
Clinical, histopathologic, and molecular markers of prognosis: toward a new disease risk stratification system for medulloblastoma
A Gajjar, R Hernan, M Kocak, C Fuller, Y Lee, PJ McKinnon, D Wallace, ...
Journal of Clinical Oncology 22 (6), 984-993, 2004
3542004
Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer
K Spring, F Ahangari, SP Scott, P Waring, DM Purdie, PC Chen, ...
Nature genetics 32 (1), 185-190, 2002
3252002
Loss of suppressor-of-fused function promotes tumorigenesis
Y Lee, R Kawagoe, K Sasai, Y Li, HR Russell, T Curran, PJ McKinnon
Oncogene 26 (44), 6442-6447, 2007
2782007
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair
D Simsek, A Furda, Y Gao, J Artus, E Brunet, AK Hadjantonakis, ...
Nature 471 (7337), 245-248, 2011
2592011
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