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Lauren Marie Gittings
Lauren Marie Gittings
Barrow Neurological Institute
在 barrowneuro.org 的电子邮件经过验证
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引用次数
引用次数
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DNAJ Proteins in neurodegeneration: essential and protective factors
C Zarouchlioti, DA Parfitt, W Li, LM Gittings, ME Cheetham
Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018
1172018
C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A
TG Moens, T Niccoli, KM Wilson, ML Atilano, N Birsa, LM Gittings, ...
Acta Neuropathologica 137, 487-500, 2019
1122019
The role of hnRNPs in frontotemporal dementia and amyotrophic lateral sclerosis
A Bampton, LM Gittings, P Fratta, T Lashley, A Gatt
Acta Neuropathologica 140 (5), 599-623, 2020
792020
Hypertonic stress causes cytoplasmic translocation of neuronal, but not astrocytic, FUS due to impaired transportin function
EM Hock, Z Maniecka, M Hruska-Plochan, S Reber, F Laferrière, SS MK, ...
Cell reports 24 (4), 987-1000. e7, 2018
542018
Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity
LM Gittings, S Boeynaems, D Lightwood, A Clargo, S Topia, L Nakayama, ...
Acta neuropathologica 139, 407-410, 2020
372020
Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS
LM Gittings, SC Foti, BC Benson, P Gami-Patel, AM Isaacs, T Lashley
Acta neuropathologica communications 7, 1-13, 2019
332019
Recent advances in understanding amyotrophic lateral sclerosis and emerging therapies
LM Gittings, R Sattler
Faculty reviews 9, 2020
272020
Cryptic exon detection and transcriptomic changes revealed in single-nuclei RNA sequencing of C9ORF72 patients spanning the ALS-FTD spectrum
LM Gittings, EB Alsop, J Antone, M Singer, TG Whitsett, R Sattler, ...
Acta neuropathologica 146 (3), 433-450, 2023
122023
Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system
E Bolukbasi, NS Woodling, DK Ivanov, J Adcott, A Foley, A Rajasingam, ...
Proceedings of the National Academy of Sciences 118 (8), e2011491118, 2021
122021
Moderate intrinsic phenotypic alterations in C9orf72 ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features
I Lorenzini, E Alsop, J Levy, LM Gittings, D Lall, BE Rabichow, S Moore, ...
Frontiers in cellular neuroscience 17, 1179796, 2023
92023
Activated iPSC-microglia from C9orf72 ALS/FTD patients exhibit endosomal-lysosomal dysfunction
I Lorenzini, E Alsop, J Levy, LM Gittings, BE Rabichow, D Lall, S Moore, ...
BioRxiv, 2020.09. 03.277459, 2020
82020
Modelling TDP-43 proteinopathy in Drosophila uncovers shared and neuron-specific targets across ALS and FTD relevant circuits
RK Godfrey, E Alsop, RT Bjork, BS Chauhan, HC Ruvalcaba, J Antone, ...
Acta neuropathologica communications 11 (1), 168, 2023
12023
Cellular and molecular phenotypes of C9orf72 ALS/FTD patient derived iPSC-microglia mono-cultures
I Lorenzini, E Alsop, J Levy, LM Gittings, D Lall, BE Rabichow, S Moore, ...
12020
The expression and presence of RNA binding proteins in FTLD-TDP
SC Foti, LM Gittings, CE Toomey, YA Asi, T Lashley
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 45, 49-49, 2019
2019
In vitro and pathological investigation of dipeptide repeat proteins in C9orf72 linked frontotemporal dementia and amyotrophic lateral sclerosis
LM Gittings
UCL (University College London), 2018
2018
Heterogeneous nuclear ribonucleoprotein R in frontotemporal lobar degeneration
L Gittings, B Benson, A Issacs, T Lashley
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 44, 31-31, 2018
2018
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