Modeling ALS with motor neurons derived from human induced pluripotent stem cells S Sances, LI Bruijn, S Chandran, K Eggan, R Ho, JR Klim, MR Livesey, ... Nature neuroscience 19 (4), 542-553, 2016 | 305 | 2016 |
The GluK4 kainate receptor subunit regulates memory, mood, and excitotoxic neurodegeneration ER Lowry, A Kruyer, EH Norris, CR Cederroth, S Strickland Neuroscience 235, 215-225, 2013 | 57 | 2013 |
Protein prenylation constitutes an endogenous brake on axonal growth H Li, T Kuwajima, D Oakley, E Nikulina, J Hou, WS Yang, ER Lowry, ... Cell reports 16 (2), 545-558, 2016 | 56 | 2016 |
A stem Cell-Based screening platform identifies compounds that desensitize motor neurons to endoplasmic reticulum stress S Thams, ER Lowry, MH Larraufie, KJ Spiller, H Li, DJ Williams, P Hoang, ... Molecular Therapy 27 (1), 87-101, 2019 | 46 | 2019 |
Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents PH Bos, ER Lowry, J Costa, S Thams, A Garcia-Diaz, A Zask, H Wichterle, ... Cell chemical biology 26 (12), 1703-1715. e37, 2019 | 45 | 2019 |
Standardized reporter systems for purification and imaging of human pluripotent stem cell-derived motor neurons and other cholinergic cells A Garcia-Diaz, G Efe, K Kabra, ER Lowry, N Shneider, B Corneo, ... Neuroscience, 2020 | 11 | 2020 |
Yielding substrates for neurons ER Lowry, CE Henderson Nature materials 13 (6), 543-544, 2014 | 7 | 2014 |
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective HW Ong, Y Liang, W Richardson, ER Lowry, CI Wells, X Chen, M Silvestre, ... ACS Chemical Neuroscience 14 (9), 1672-1685, 2023 | 2 | 2023 |
Compounds, compositions, and methods for suppressing toxic endoplasmic reticulum stress ERL Brent R Stockwell, Hynek Wichterle, Pieter Bos, Arie Zask, Sebastian Thams US Patent App. 17/009,450, 2021 | 2* | 2021 |
A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective HW Ong, Y Liang, W Richardson, ER Lowry, CI Wells, X Chen, M Silvestre, ... bioRxiv, 2023 | 1 | 2023 |
Enhanced protein misfolding in patient-derived models of amyotrophic lateral sclerosis E Forsgren, M Lehmann, M Weygandt Mathis, I Keskin, P Zetterström, ... | 1 | 2017 |
The GluK4 Kainate Receptor Subunit Regulates Mood, Memory and Excitotoxic Neurodegeneration ER Lowry | 1 | 2012 |
Embryonic motor neuron programming factors reactivate immature gene expression and suppress ALS pathologies in postnatal motor neurons ER Lowry, T Patel, JA Costa, E Chang, S Tariq, H Melikyan, IM Davis, ... bioRxiv, 2024 | | 2024 |
Safety and pharmacokinetics of prosetin, a novel, brain penetrant MAP4K inhibitor in development for the treatment of ALS E Fleming, E Lowry, H Wichterle, A Zask, B Stockwell, I Danielsson, ... MUSCLE & NERVE 66, S51-S52, 2022 | | 2022 |
Altered MAM function shifts mitochondrial metabolism in SOD1-mutant models of ALS D Larrea, KA Tamucci, K Kabra, K Velasco, TD Yun, M Pera, J Montesinos, ... bioRxiv, 2022.09. 22.508778, 2022 | | 2022 |