Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood–brain barrier in vivo in … WM Pardridge, YS Kang, JL Buciak, J Yang Pharmaceutical research 12, 807-816, 1995 | 376 | 1995 |
Anti-inflammatory activity of Taraxacum officinale HJ Jeon, HJ Kang, HJ Jung, YS Kang, CJ Lim, YM Kim, EH Park Journal of ethnopharmacology 115 (1), 82-88, 2008 | 283 | 2008 |
Transport of Human Recombinant Brain-Derived Neurotrophic Factor (BDNF) Through the Rat Blood−Brain Barrier in Vivo Using Vector-Mediated Peptide Drug … WM Pardridge, YS Kang, JL Buciak Pharmaceutical research 11, 738-746, 1994 | 277 | 1994 |
Vector-mediated delivery of a polyamide (" peptide") nucleic acid analogue through the blood-brain barrier in vivo. WM Pardridge, RJ Boado, YS Kang Proceedings of the National Academy of Sciences 92 (12), 5592-5596, 1995 | 264 | 1995 |
Upregulation of blood-brain barrier GLUT1 glucose transporter protein and mRNA in experimental chronic hypoglycemia AK Kumagai, YS Kang, RJ Boado, WM Pardridge Diabetes 44 (12), 1399-1404, 1995 | 217 | 1995 |
Brain microvascular and astrocyte localization of P‐glycoprotein WM Pardridge, PL Golden, YS Kang, U Bickel Journal of neurochemistry 68 (3), 1278-1285, 1997 | 201 | 1997 |
Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells S Mori, H Takanaga, S Ohtsuki, T Deguchi, YS Kang, K Hosoya, ... Journal of Cerebral Blood Flow & Metabolism 23 (4), 432-440, 2003 | 190 | 2003 |
Antitumor activity of EGFR targeted pH-sensitive immunoliposomes encapsulating gemcitabine in A549 xenograft nude mice IY Kim, YS Kang, DS Lee, HJ Park, EK Choi, YK Oh, HJ Son, JS Kim Journal of Controlled Release 140 (1), 55-60, 2009 | 189 | 2009 |
Blood-brain barrier permeability to morphine-6-glucuronide is markedly reduced compared with morphine D Wu, YS Kang, U Bickel, WM Pardridge Drug metabolism and disposition 25 (6), 768-771, 1997 | 168 | 1997 |
Poor permeability of morphine 3-glucuronide and morphine 6-glucuronide through the blood-brain barrier in the rat. U Bickel, OP Schumacher, YS Kang, K Voigt Journal of Pharmacology and Experimental Therapeutics 278 (1), 107-113, 1996 | 139 | 1996 |
In vivo demonstration of subcellular localization of anti-transferrin receptor monoclonal antibody-colloidal gold conjugate in brain capillary endothelium. U Bickel, YS Kang, T Yoshikawa, WM Pardridge Journal of Histochemistry & Cytochemistry 42 (11), 1493-1497, 1994 | 133 | 1994 |
Regulation of taurine transport at the blood–brain barrier by tumor necrosis factor‐α, taurine and hypertonicity YS Kang, S Ohtsuki, H Takanaga, M Tomi, K Hosoya, T Terasaki Journal of neurochemistry 83 (5), 1188-1195, 2002 | 132 | 2002 |
Transferrin-antibody fusion proteins are effective in brain targeting. SU Shin, P Friden, M Moran, T Olson, YS Kang, WM Pardridge, ... Proceedings of the National Academy of Sciences 92 (7), 2820-2824, 1995 | 130 | 1995 |
Absorptive-mediated endocytosis of a dynorphin-like analgesic peptide, E-2078 into the blood-brain barrier. T Terasaki, K Hirai, H Sato, YS Kang, A Tsuji Journal of Pharmacology and Experimental Therapeutics 251 (1), 351-357, 1989 | 118 | 1989 |
An antibody-avidin fusion protein specific for the transferrin receptor serves as a delivery vehicle for effective brain targeting: initial applications in anti-HIV antisense … ML Penichet, YS Kang, WM Pardridge, SL Morrison, SU Shin The Journal of Immunology 163 (8), 4421-4426, 1999 | 114 | 1999 |
Organic anion transporter 3 is involved in the brain‐to‐blood efflux transport of thiopurine nucleobase analogs S Mori, S Ohtsuki, H Takanaga, T Kikkawa, YS Kang, T Terasaki Journal of neurochemistry 90 (4), 931-941, 2004 | 103 | 2004 |
Blood-brain barrier transport and brain metabolism of adenosine and adenosine analogs. WM Pardridge, T Yoshikawa, YS Kang, LP Miller Journal of Pharmacology and Experimental Therapeutics 268 (1), 14-18, 1994 | 102 | 1994 |
Use of neutral avidin improves pharmacokinetics and brain delivery of biotin bound to an avidin-monoclonal antibody conjugate. YS Kang, WM Pardridge Journal of Pharmacology and Experimental Therapeutics 269 (1), 344-350, 1994 | 101 | 1994 |
Anti‐inflammatory mechanism of ginsenoside Rh1 in lipopolysaccharide‐stimulated microglia: critical role of the protein kinase A pathway and hemeoxygenase‐1 expression JS Jung, JA Shin, EM Park, JE Lee, YS Kang, SW Min, DH Kim, JW Hyun, ... Journal of neurochemistry 115 (6), 1668-1680, 2010 | 100 | 2010 |
Brain uptake and the analgesic effect of oxytocin—its usefulness as an analgesic agent YS Kang, JH Park Archives of pharmacal research 23, 391-395, 2000 | 84 | 2000 |