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J. Arjuna Ratnayaka
J. Arjuna Ratnayaka
Associate Professor
在 soton.ac.uk 的电子邮件经过验证 - 首页
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引用次数
引用次数
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13148*2021
Dementia of the eye: the role of amyloid beta in retinal degeneration
JA Ratnayaka, LC Serpell, AJ Lotery
Eye 29 (8), 1013-1026, 2015
1772015
A vesicle superpool spans multiple presynaptic terminals in hippocampal neurons
K Staras, T Branco, JJ Burden, K Pozo, K Darcy, V Marra, A Ratnayaka, ...
Neuron 66 (1), 37-44, 2010
1722010
Visualization of co-localization in Aβ42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death
V Soura, M Stewart-Parker, TL Williams, A Ratnayaka, J Atherton, ...
Biochemical Journal 441 (2), 579-590, 2012
822012
Impaired cargo clearance in the retinal pigment epithelium (RPE) underlies irreversible blinding diseases
E Keeling, AJ Lotery, DA Tumbarello, JA Ratnayaka
Cells 7 (2), 16, 2018
722018
Recruitment of resting vesicles into recycling pools supports NMDA receptor‐dependent synaptic potentiation in cultured hippocampal neurons
A Ratnayaka, V Marra, D Bush, JJ Burden, T Branco, K Staras
The Journal of physiology 590 (7), 1585-1597, 2012
722012
Sorsby fundus dystrophy–a review of pathology and disease mechanisms
DRG Christensen, FE Brown, AJ Cree, JA Ratnayaka, AJ Lotery
Experimental eye research 165, 35-46, 2017
642017
Unexpected intracellular localization of the AMD‐associated cystatin C variant
L Paraoan, A Ratnayaka, DG Spiller, P Hiscott, MRH White, I Grierson
Traffic 5 (11), 884-895, 2004
602004
Identification of a functionally significant tri-allelic genotype in the Tyrosinase gene (TYR) causing hypomorphic oculocutaneous albinism (OCA1B)
CS Norman, L O’Gorman, J Gibson, RJ Pengelly, D Baralle, ...
Scientific reports 7 (1), 4415, 2017
582017
Extrasynaptic vesicle recycling in mature hippocampal neurons
A Ratnayaka, V Marra, T Branco, K Staras
Nature communications 2 (1), 531, 2011
512011
The complexities underlying age-related macular degeneration: could amyloid beta play an important role?
SA Lynn, E Keeling, R Munday, G Gabha, H Griffiths, AJ Lotery, ...
Neural regeneration research 12 (4), 538-548, 2017
472017
Progress in developing rodent models of age-related macular degeneration (AMD)
SPS Pandi, JA Ratnayaka, AJ Lotery, JL Teeling
Experimental Eye Research 203, 108404, 2021
342021
The Diverse Roles of TIMP-3: Insights into degenerative diseases of the senescent retina and brain
JM Dewing, RO Carare, AJ Lotery, JA Ratnayaka
Cells 9 (1), 39, 2019
292019
Ex-vivo models of the Retinal Pigment Epithelium (RPE) in long-term culture faithfully recapitulate key structural and physiological features of native RPE
SA Lynn, G Ward, E Keeling, JA Scott, AJ Cree, DA Johnston, A Page, ...
Tissue and Cell 49 (4), 447-460, 2017
292017
Retinoic acid receptor α expression and cutaneous ageing
REB Watson, JA Ratnayaka, RCC Brooke, S Yee-Sit-Yu, P Ancian, ...
Mechanisms of ageing and development 125 (7), 465-473, 2004
262004
The Alzheimer's-related amyloid beta peptide is internalised by R28 neuroretinal cells and disrupts the microtubule associated protein 2 (MAP-2)
G Taylor-Walker, SA Lynn, E Keeling, R Munday, DA Johnston, A Page, ...
Experimental eye research 153, 110-121, 2016
212016
3D-reconstructed retinal pigment epithelial cells provide insights into the anatomy of the outer retina
E Keeling, DS Chatelet, NYT Tan, F Khan, R Richards, T Thisainathan, ...
International journal of molecular sciences 21 (21), 8408, 2020
192020
Oxidative stress and dysfunctional intracellular traffic linked to an unhealthy diet results in impaired cargo transport in the retinal pigment epithelium (RPE)
E Keeling, DS Chatelet, DA Johnston, A Page, DA Tumbarello, AJ Lotery, ...
Molecular nutrition & food research 63 (15), 1800951, 2019
192019
A lasered mouse model of retinal degeneration displays progressive outer retinal pathology providing insights into early geographic atrophy
P Ibbett, SV Goverdhan, E Pipi, JK Chouhan, E Keeling, EM Angus, ...
Scientific Reports 9 (1), 7475, 2019
192019
A dual Golgi-and mitochondria-localised Ala25Ser precursor cystatin C: an additional tool for characterising intracellular mis-localisation leading to increased AMD susceptibility
A Ratnayaka, L Paraoan, DG Spiller, P Hiscott, G Nelson, MRH White, ...
Experimental eye research 84 (6), 1135-1139, 2007
192007
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