IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA RC Fleith, HV Mears, XY Leong, TJ Sanford, E Emmott, SC Graham, ... Nucleic acids research 46 (10), 5269-5285, 2018 | 109 | 2018 |
Better together: the role of IFIT protein-protein interactions in the antiviral response. H Mears, T Sweeney Journal of General Virology, 2018 | 104 | 2018 |
Three-dose vaccination elicits neutralising antibodies against omicron M Wu, EC Wall, EJ Carr, R Harvey, H Townsley, HV Mears, L Adams, ... The Lancet 399 (10326), 715-717, 2022 | 100 | 2022 |
Circularization of flavivirus genomic RNA inhibits de novo translation initiation TJ Sanford, HV Mears, T Fajardo Jr, N Locker, TR Sweeney Nucleic acids research 47 (18), 9789-9802, 2019 | 54 | 2019 |
WHO's Therapeutics and COVID-19 Living Guideline on mAbs needs to be reassessed MY Wu, EJ Carr, R Harvey, HV Mears, S Kjaer, H Townsley, A Hobbs, ... The Lancet 400 (10369), 2193-2196, 2022 | 45 | 2022 |
The flavivirus polymerase NS5 regulates translation of viral genomic RNA T Fajardo Jr, TJ Sanford, HV Mears, A Jasper, S Storrie, DS Mansur, ... Nucleic acids research 48 (9), 5081-5093, 2020 | 31 | 2020 |
Neutralising immunity to omicron sublineages BQ. 1.1, XBB, and XBB. 1.5 in healthy adults is boosted by bivalent BA. 1-containing mRNA vaccination and previous Omicron infection EJ Carr, MY Wu, J Gahir, R Harvey, H Townsley, C Bailey, AS Fowler, ... The Lancet Infectious Diseases 23 (7), 781-784, 2023 | 13 | 2023 |
Ifit1 regulates norovirus infection and enhances the interferon response in murine macrophage-like cells HV Mears, E Emmott, Y Chaudhry, M Hosmillo, IG Goodfellow, ... Wellcome Open Research 4, 2019 | 13 | 2019 |
Emergence of new subgenomic mRNAs in SARS-CoV-2 HV Mears, GR Young, T Sanderson, R Harvey, M Crawford, DM Snell, ... BioRxiv, 2022.04. 20.488895, 2022 | 11 | 2022 |
Non-hospitalised, vaccinated adults with COVID-19 caused by Omicron BA. 1 and BA. 2 present with changing symptom profiles compared to those with Delta despite similar viral … H Townsley, EJ Carr, TW Russell, L Adams, HV Mears, C Bailey, ... MedRxiv, 2022 | 6 | 2022 |
Mouse Ifit1b is a cap1-RNA–binding protein that inhibits mouse coronavirus translation and is regulated by complexing with Ifit1c HV Mears, TR Sweeney Journal of Biological Chemistry 295 (51), 17781-17801, 2020 | 6 | 2020 |
Combined analyses of within-host SARS-CoV-2 viral kinetics and information on past exposures to the virus in a human cohort identifies intrinsic differences of Omicron and … TW Russell, H Townsley, S Abbott, J Hellewell, EJ Carr, LAC Chapman, ... Plos Biology 22 (1), e3002463, 2024 | 4 | 2024 |
Within-host SARS-CoV-2 viral kinetics informed by complex life course exposures reveals different intrinsic properties of Omicron and Delta variants TW Russell, H Townsley, S Abbott, J Hellewell, EJ Carr, L Chapman, ... medRxiv, 2023 | 3 | 2023 |
SARS-CoV-2 mucosal neutralising immunity after vaccination EJ Carr, G Dowgier, D Greenwood, LS Herman, A Hobbs, M Ragno, ... The Lancet Infectious Diseases 24 (1), e4-e5, 2024 | 2 | 2024 |
COVID-19 in non-hospitalised adults caused by either SARS-CoV-2 sub-variants Omicron BA. 1, BA. 2, BA. 4/5 or Delta associates with similar illness duration, symptom severity … H Townsley, J Gahir, TW Russell, D Greenwood, EJ Carr, M Dyke, ... Plos one 19 (3), e0294897, 2024 | 1 | 2024 |
Dichotomy of neutralizing antibody, B cell and T cell responses to SARS-CoV-2 vaccination and protection in healthy adults EJ Carr, H Townsley, MY Wu, KA Wilkinson, PS Hobson, D Levi, ... bioRxiv, 2023.05. 24.541920, 2023 | 1 | 2023 |
COVID-19 in non-hospitalised adults caused by either SARS-CoV-2 sub-variants Omicron BA. 1, BA. 2, BA. 5 or Delta associates with similar illness duration, symptom severity and … H Townsley, J Gahir, TW Russell, EJ Carr, M Dyke, L Adams, M Miah, ... medRxiv, 2022.07. 07.22277367, 2022 | 1 | 2022 |
Dissecting the molecular mechanisms of coronavirus genome packaging H Mears, Z Yang, K Raibuzis, C Gilbride, F Lee, A Chakrabarti, D Bauer | | 2024 |
ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication GJ Pearson, HV Mears, M Broncel, AP Snijders, DLV Bauer, JG Carlton Science Advances 10 (14), eadl5012, 2024 | | 2024 |
33 Fourth dose bivalent mRNA vaccines containing BA. 1 significantly augment neutralising antibody titres against SARS-COV-2 Omicron sub-lineages XBB and BQ. 1.1 in healthy adults M Wu, E Carr, R Harvey, J Gahir, H Townsley, G Dowgier, A Hobbs, ... Clinical Infection in Practice 20, 100260, 2023 | | 2023 |