A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis T Muchamuel, M Basler, MA Aujay, E Suzuki, KW Kalim, C Lauer, ... Nature medicine 15 (7), 781-787, 2009 | 691 | 2009 |
Immuno-and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity EM Huber, M Basler, R Schwab, W Heinemeyer, CJ Kirk, M Groettrup, ... Cell 148 (4), 727-738, 2012 | 550 | 2012 |
Proteasomes in immune cells: more than peptide producers? M Groettrup, CJ Kirk, M Basler Nature Reviews Immunology 10 (1), 73-78, 2010 | 422 | 2010 |
The immunoproteasome in antigen processing and other immunological functions M Basler, CJ Kirk, M Groettrup Current opinion in immunology 25 (1), 74-80, 2013 | 308 | 2013 |
Prevention of experimental colitis by a selective inhibitor of the immunoproteasome M Basler, M Dajee, C Moll, M Groettrup, CJ Kirk The Journal of Immunology 185 (1), 634-641, 2010 | 301 | 2010 |
Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis M Basler, S Mundt, T Muchamuel, C Moll, J Jiang, M Groettrup, CJ Kirk EMBO molecular medicine 6 (2), 226-238, 2014 | 186 | 2014 |
Immunoproteasome subunit LMP7 deficiency and inhibition suppresses Th1 and Th17 but enhances regulatory T cell differentiation KW Kalim, M Basler, CJ Kirk, M Groettrup The Journal of Immunology 189 (8), 4182-4193, 2012 | 186 | 2012 |
An altered T cell repertoire in MECL-1-deficient mice M Basler, J Moebius, L Elenich, M Groettrup, JJ Monaco The Journal of Immunology 176 (11), 6665-6672, 2006 | 148 | 2006 |
The immunoproteasome: a novel drug target for autoimmune diseases M Basler, S Mundt, A Bitzer, C Schmidt, M Groettrup Clin Exp Rheumatol 33 (4 Suppl 92), S74-9, 2015 | 144 | 2015 |
Immunodominance of an antiviral cytotoxic T cell response is shaped by the kinetics of viral protein expression HC Probst, K Tschannen, A Gallimore, M Martinic, M Basler, T Dumrese, ... The Journal of Immunology 171 (10), 5415-5422, 2003 | 139 | 2003 |
Immuno-and constitutive proteasomes do not differ in their abilities to degrade ubiquitinated proteins JA Nathan, V Spinnenhirn, G Schmidtke, M Basler, M Groettrup, ... Cell 152 (5), 1184-1194, 2013 | 134 | 2013 |
Immunoproteasomes down-regulate presentation of a subdominant T cell epitope from lymphocytic choriomeningitis virus M Basler, N Youhnovski, M Van Den Broek, M Przybylski, M Groettrup The Journal of Immunology 173 (6), 3925-3934, 2004 | 134 | 2004 |
The proteasome inhibitor bortezomib enhances the susceptibility to viral infection M Basler, C Lauer, U Beck, M Groettrup The Journal of Immunology 183 (10), 6145-6150, 2009 | 125 | 2009 |
Long-lived signal peptide of lymphocytic choriomeningitis virus glycoprotein pGP-C M Froeschke, M Basler, M Groettrup, B Dobberstein Journal of Biological Chemistry 278 (43), 41914-41920, 2003 | 116 | 2003 |
Immunoproteasomes are essential for survival and expansion of T cells in virus‐infected mice J Moebius, M van den Broek, M Groettrup, M Basler European journal of immunology 40 (12), 3439-3449, 2010 | 111 | 2010 |
A cytomegalovirus inhibitor of gamma interferon signaling controls immunoproteasome induction S Khan, A Zimmermann, M Basler, M Groettrup, H Hengel Journal of virology 78 (4), 1831-1842, 2004 | 99 | 2004 |
Cross-presentation of the long-lived lymphocytic choriomeningitis virus nucleoprotein does not require neosynthesis and is enhanced via heat shock proteins S Basta, R Stoessel, M Basler, M van den Broek, M Groettrup The Journal of Immunology 175 (2), 796-805, 2005 | 90 | 2005 |
Reduced immunoproteasome formation and accumulation of immunoproteasomal precursors in the brains of lymphocytic choriomeningitis virus-infected mice M Kremer, A Henn, C Kolb, M Basler, J Moebius, B Guillaume, M Leist, ... The Journal of Immunology 185 (9), 5549-5560, 2010 | 80 | 2010 |
Co‐inhibition of immunoproteasome subunits LMP2 and LMP7 is required to block autoimmunity M Basler, MM Lindstrom, JJ LaStant, JM Bradshaw, TD Owens, C Schmidt, ... EMBO reports 19 (12), e46512, 2018 | 69 | 2018 |
The ubiquitin-like modifier FAT10 decorates autophagy-targeted Salmonella and contributes to Salmonella resistance in mice V Spinnenhirn, H Farhan, M Basler, A Aichem, A Canaan, M Groettrup Journal of cell science 127 (22), 4883-4893, 2014 | 65 | 2014 |