GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis DM Kremer, BS Nelson, L Lin, EL Yarosz, CJ Halbrook, SA Kerk, ... Nature Communications 12 (1), 1-13, 2021 | 163 | 2021 |
Metabolic regulation of ferroptosis in the tumor microenvironment NE Mbah, CA Lyssiotis Journal of Biological Chemistry, 101617, 2022 | 55 | 2022 |
The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma Z Li, NE Mbah, JH Overmeyer, JG Sarver, S George, CJ Trabbic, ... BMC cancer 19 (1), 1-20, 2019 | 53 | 2019 |
OXPHOS promotes apoptotic resistance and cellular persistence in TH17 cells in the periphery and tumor microenvironment HS Hong, NE Mbah, M Shan, K Loesel, L Lin, P Sajjakulnukit, LO Correa, ... Science Immunology 7 (77), eabm8182, 2022 | 39 | 2022 |
Disruption of endolysosomal trafficking pathways in glioma cells by methuosis-inducing indole-based chalcones NE Mbah, JH Overmeyer, WA Maltese Cell biology and toxicology 33 (3), 263-282, 2017 | 36 | 2017 |
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome BJ Golbourn, ME Halbert, K Halligan, S Varadharajan, B Krug, NE Mbah, ... Nature Cancer, 1-20, 2022 | 29 | 2022 |
Vacuole-inducing compounds that disrupt endolysosomal trafficking stimulate production of exosomes by glioblastoma cells Z Li, NE Mbah, WA Maltese Molecular and cellular biochemistry 439 (1), 1-9, 2018 | 15 | 2018 |
Therapeutic targeting of differentiation state-dependent metabolic vulnerabilities in DIPG NE Mbah, AL Myers, C Chung, JK Thompson, HS Hong, P Sajjakulnukit, ... bioRxiv, 2022 | 4 | 2022 |
Non-apoptotic death induced in glioma cells by the indole-based chalcone, MOMIPP, involves disruption of endolysosomal trafficking and ER stress NE Mbah, AD Trunk, BA Dewitt, JH Overmeyer, WA Maltese Cancer Research 74 (19 Supplement), 1343-1343, 2014 | 3 | 2014 |
Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome BJ Golbourn, ME Halbert, K Halligan, S Varadharajan, B Krug, NE Mbah, ... Nature Cancer, 1-1, 2022 | 2 | 2022 |
Histone H3 K27M-mediated regulation of cancer cell stemness and differentiation in diffuse midline glioma M Sharma, I Barravecchia, B Magnuson, SF Ferris, A Apfelbaum, ... Neoplasia 44, 100931, 2023 | 1 | 2023 |
DIPG-36. H3K27M HISTONE MUTANT GLIOMAS ARE SENSITIVE TO METHIONINE LOSS AND MAT2A INHIBITION THROUGH A NOVEL FEEDBACK MECHANISM BETWEEN AMD1 AND METTL16 A Chilukuri, M Halbert, B Golbourn, S Varadharajan, B Krug, N Mbah, ... Neuro-Oncology 25 (Supplement_1), i21-i21, 2023 | | 2023 |
TMET-09. LOSS OF MAT2A COMPROMISES METHIONINE METABOLISM AND REPRESENTS A VULNERABILITY IN H3K27M MUTANT GLIOMAS M Halbert, B Golbourn, K Halligan, S Varadharajan, B Krug, N Mbah, ... Neuro-Oncology 24 (Supplement_7), vii263-vii263, 2022 | | 2022 |
DDRE-30. THERAPEUTIC TARGETING OF DISRUPTED METABOLIC STATE IN DIFFUSE INTRINSIC PONTINE GLIOMA N Mbah, A Myers, C Chung, J Thompson, M Shan, H Hong, C Koschmann, ... Neuro-oncology Advances 3 (Suppl 1), i13, 2021 | | 2021 |
OXPHOS Promotes Apoptotic Resistance and Persistence in TH17 cells H Hong, N Mbah, M Shan, K Loesel, L Lin, P Sajjakulnukit, A Andren, ... bioRxiv, 2021 | | 2021 |