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Xiaozhuo LIU, PhD
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Intron retention is a hallmark and spliceosome represents a therapeutic vulnerability in aggressive prostate cancer
D Zhang, Q Hu, X Liu, Y Ji, HP Chao, Y Liu, A Tracz, J Kirk, S Buonamici, ...
Nature communications 11 (1), 2089, 2020
1042020
Telomerase protects werner syndrome lineage-specific stem cells from premature aging
HH Cheung, X Liu, L Canterel-Thouennon, L Li, C Edmonson, ...
Stem cell reports 2 (4), 534-546, 2014
1012014
Ursolic acid induces doxorubicin-resistant HepG2 cell death via the release of apoptosis-inducing factor
L Yang, X Liu, Z Lu, JYW Chan, LL Zhou, KP Fung, P Wu, S Wu
Cancer Letters 298 (1), 128-138, 2010
922010
Pheophorbide a based photodynamic therapy induces apoptosis via mitochondrial-mediated pathway in human uterine carcinosarcoma
PMK Tang, XZ Liu, DM Zhang, WP Fong, KP Fung
Cancer biology & therapy 8 (6), 533-539, 2009
782009
Polyphyllin D, a steroidal saponin from Paris polyphylla, inhibits endothelial cell functions in vitro and angiogenesis in zebrafish embryos in vivo
JYW Chan, JCM Koon, X Liu, M Detmar, B Yu, SK Kong, KP Fung
Journal of ethnopharmacology 137 (1), 64-69, 2011
732011
Idiopathic autism: cellular and molecular phenotypes in pluripotent stem cell-derived neurons
X Liu, E Campanac, HH Cheung, MN Ziats, L Canterel-Thouennon, ...
Molecular neurobiology 54, 4507-4523, 2017
692017
Distribution of melamine in rat foetuses and neonates
CY Chu, KO Chu, JYW Chan, XZ Liu, CS Ho, CK Wong, CM Lau, TL Ting, ...
Toxicology letters 199 (3), 398-402, 2010
392010
Apoptosis: Reprogramming and the fate of mature cells
HH Cheung, X Liu, OM Rennert
International Scholarly Research Notices 2012 (1), 685852, 2012
332012
Inhibition of CDK9 activity compromises global splicing in prostate cancer cells
Q Hu, N Poulose, S Girmay, A Helevä, D Doultsinos, A Gondane, ...
RNA biology 18 (sup2), 722-729, 2021
162021
Reconstitution and Analyses of RNA Interactions with Eukaryotic Translation Initiation Factors and Ribosomal Preinitiation Complexes
L Xiaozhuo, S Peter, J., S Ansuman, W Sarah, E.
Methods, 2019
122019
MicroRNA-34a, prostate cancer stem cells, and therapeutic development
W Li, X Liu, EM Dougherty, DG Tang
Cancers 14 (18), 4538, 2022
102022
Prostate cancer as a dedifferentiated organ: androgen receptor, cancer stem cells, and cancer stemness
X Liu, W Li, I Puzanov, DW Goodrich, G Chatta, DG Tang
Essays in Biochemistry 66 (4), 291-303, 2022
102022
Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota …
F Li, X Ling, S Chakraborty, C Fountzilas, J Wang, A Jamroze, X Liu, ...
Journal of Experimental & Clinical Cancer Research 42 (1), 213, 2023
42023
Deletion of the N-terminal Domain of Yeast Eukaryotic Initiation Factor 4B Reprograms Translation and Reduces Growth in Urea
X Liu, H Moshiri, Q He, A Sahoo, SE Walker
Frontiers in Molecular Biosciences, 1292, 2022
32022
Developing Folate-Conjugated miR-34a Therapeutic for Prostate Cancer: Challenges and Promises
W Li, Y Wang, X Liu, S Wu, M Wang, SG Turowski, JA Spernyak, A Tracz, ...
International Journal of Molecular Sciences 25 (4), 2123, 2024
22024
Dysregulated alternative splicing landscape identifies intron retention as a hallmark and spliceosome as a therapeutic vulnerability in aggressive prostate cancer
D Zhang, Q Hu, Y Ji, HP Chao, A Tracz, J Kirk, S Buonamici, P Zhu, ...
BioRxiv, 634402, 2019
22019
Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells
JS Kirk, J Wang, M Long, S Rosario, A Tracz, Y Ji, R Kumar, X Liu, ...
Cell Stem Cell, 2024
12024
Targeted dual degradation of HER2 and EGFR obliterates oncogenic signaling, overcomes therapy resistance, and inhibits metastatic lesions in HER2-positive breast cancer models
L Yang, A Bhattacharya, D Peterson, Y Li, X Liu, E Marangoni, V Robila, ...
Drug Resistance Updates 74, 101078, 2024
2024
A dual degrader of HER2 and EGFR obliterates oncogenic signaling, overcomes therapy resistance, and inhibits metastatic lesions in HER2-positive breast cancer models
L Yang, A Bhattacharya, D Peterson, Y Li, X Liu, E Marangoni, V Robila, ...
Cancer Research 84 (6_Supplement), 4661-4661, 2024
2024
Further development of microRNA-34a therapeutics to target castration-resistant prostate cancer
W Li, X Liu, AM Abdelaal, S Kasireddy, Y Su, Y Wu, AL Kasinski, DG Tang
Cancer Research 83 (7_Supplement), 2716-2716, 2023
2023
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