| Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis J Skokowa, D Steinemann, JE Katsman-Kuipers, C Zeidler, O Klimenkova, ... Blood, The Journal of the American Society of Hematology 123 (14), 2229-2237, 2014 | 152 | 2014 |
| The role of sirtuin 2 activation by nicotinamide phosphoribosyltransferase in the aberrant proliferation and survival of myeloid leukemia cells L Dan, O Klimenkova, M Klimiankou, JH Klusman, ... Haematologica 97 (4), 551, 2012 | 122 | 2012 |
| Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF–triggered granulopoiesis J Skokowa, M Klimiankou, O Klimenkova, D Lan, K Gupta, K Hussein, ... Nature medicine 18 (10), 1550-1559, 2012 | 89 | 2012 |
| A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation O Klimenkova, W Ellerbeck, M Klimiankou, M Ünalan, S Kandabarau, ... Blood, The Journal of the American Society of Hematology 123 (8), 1239-1249, 2014 | 52 | 2014 |
| ELANE mutant–specific activation of different UPR pathways in congenital neutropenia R Nustede, M Klimiankou, O Klimenkova, I Kuznetsova, C Zeidler, K Welte, ... British Journal of Haematology 172 (2), 219-227, 2016 | 40 | 2016 |
| CRISPR/Cas9-mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital … M Nasri, M Ritter, P Mir, B Dannenmann, N Aghaallaei, D Amend, ... Haematologica 105 (3), 598, 2020 | 36 | 2020 |
| GM-CSF stimulates granulopoiesis in a congenital neutropenia patient with loss-of-function biallelic heterozygous CSF3R mutations M Klimiankou, O Klimenkova, M Uenalan, A Zeidler, S Mellor-Heineke, ... Blood, The Journal of the American Society of Hematology 126 (15), 1865-1867, 2015 | 35 | 2015 |
| LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis T Morishima, AC Krahl, M Nasri, Y Xu, N Aghaallaei, B Findik, ... Blood, The Journal of the American Society of Hematology 134 (14), 1159-1175, 2019 | 25 | 2019 |
| Bortezomib inhibits STAT5-dependent degradation of LEF-1, inducing granulocytic differentiation in congenital neutropenia CD34+ cells K Gupta, I Kuznetsova, O Klimenkova, M Klimiankou, J Meyer, ... Blood, The Journal of the American Society of Hematology 123 (16), 2550-2561, 2014 | 23 | 2014 |
| Role of CSF3R mutations in the pathomechanism of congenital neutropenia and secondary acute myeloid leukemia M Klimiankou, S Mellor‐Heineke, C Zeidler, K Welte, J Skokowa Annals of the New York Academy of Sciences 1370 (1), 119-125, 2016 | 22 | 2016 |
| Human iPSC-based model of severe congenital neutropenia reveals elevated UPR and DNA damage in CD34+ cells preceding leukemic transformation B Dannenmann, A Zahabi, P Mir, B Oswald, R Bernhard, M Klimiankou, ... Experimental Hematology 71, 51-60, 2019 | 20 | 2019 |
| Two cases of cyclic neutropenia with acquired CSF3R mutations, with 1 developing AML M Klimiankou, S Mellor-Heineke, O Klimenkova, E Reinel, M Uenalan, ... Blood, The Journal of the American Society of Hematology 127 (21), 2638-2641, 2016 | 20 | 2016 |
| Fluorescent labeling of CRISPR/Cas9 RNP for gene knockout in HSPCs and iPSCs reveals an essential role for GADD45b in stress response M Nasri, P Mir, B Dannenmann, D Amend, T Skroblyn, Y Xu, ... Blood advances 3 (1), 63-71, 2019 | 18 | 2019 |
| iPSC modeling of stage-specific leukemogenesis reveals BAALC as a key oncogene in severe congenital neutropenia B Dannenmann, M Klimiankou, B Oswald, A Solovyeva, J Mardan, ... Cell Stem Cell 28 (5), 906-922. e6, 2021 | 16 | 2021 |
| New insights into the pathomechanism of cyclic neutropenia P Mir, M Klimiankou, B Findik, K Hähnel, S Mellor‐Heineke, C Zeidler, ... Annals of the New York Academy of Sciences 1466 (1), 83-92, 2020 | 16 | 2020 |
| Ultra-Sensitive CSF3R Deep Sequencing in Patients With Severe Congenital Neutropenia M Klimiankou, M Uenalan, S Kandabarau, R Nustede, I Steiert, ... Frontiers in immunology 10, 116, 2019 | 15 | 2019 |
| Old drug revisited: disulfiram, NETs, and sepsis M Klimiankou, J Skokowa Blood, The Journal of the American Society of Hematology 138 (25), 2604-2605, 2021 | 8 | 2021 |
| Cooperating, congenital neutropenia–associated Csf3r and Runx1 mutations activate pro-inflammatory signaling and inhibit myeloid differentiation of mouse HSPCs M Ritter, M Klimiankou, O Klimenkova, A Schambach, D Hoffmann, ... Annals of hematology 99, 2329-2338, 2020 | 6 | 2020 |
| Efficient correction of ELANE mutations in primary HSPCs of severe congenital neutropenia patients using CRISPR/Cas9 and rAVV6 HDR repair templates MU Ritter, B Secker, M Klimiankou, M Nasri, N Aghaallaei, ... Blood 134, 1036, 2019 | 4 | 2019 |
| RUNX1 Mutations Are the Most Frequent Leukemia Associated Mutations in Congenital Neutropenia Patients J Skokowa, D Steinemann, V Makaryan, M Klimiankou, S Schnittger, ... Blood, The Journal of the American Society of Hematology 120 (21), 7-7, 2012 | 4 | 2012 |
Julia SkokowaHead Division of Translational Oncology, Department of Hematology, Oncology and Clinical Immunology, University Hospital Tuebingen, Germany在 med.uni-tuebingen.de 的电子邮件经过验证
