Cold Urticaria, Immunodeficiency, and Autoimmunity Related to PLCG2 Deletions MJ Ombrello, EF Remmers, G Sun, AF Freeman, S Datta, P Torabi-Parizi, ... New England Journal of Medicine 366 (4), 330-338, 2012 | 443 | 2012 |
A hypermorphic missense mutation in PLCG2, encoding phospholipase Cγ2, causes a dominantly inherited autoinflammatory disease with immunodeficiency Q Zhou, GS Lee, J Brady, S Datta, M Katan, A Sheikh, MS Martins, ... The American Journal of Human Genetics 91 (4), 713-720, 2012 | 382 | 2012 |
Alzheimer’s disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph L Magno, CB Lessard, M Martins, V Lang, P Cruz, Y Asi, M Katan, ... Alzheimer's research & therapy 11, 1-11, 2019 | 128 | 2019 |
Structural and functional integration of the PLCγ interaction domains critical for regulatory mechanisms and signaling deregulation TD Bunney, D Esposito, C Mas-Droux, E Lamber, RW Baxendale, ... Structure 20 (12), 2062-2075, 2012 | 98 | 2012 |
Identification of the xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 as a new target of cisplatin in breast cancer cells: molecular and cellular mechanisms of … N Ragunathan, J Dairou, B Pluvinage, M Martins, E Petit, N Janel, ... Molecular pharmacology 73 (6), 1761-1768, 2008 | 61 | 2008 |
Novel PLCG2 Mutation in a Patient With APLAID and Cutis Laxa JF Neves, R Doffinger, G Barcena-Morales, C Martins, O Papapietro, ... Frontiers in immunology 9, 2863, 2018 | 59 | 2018 |
An acetyltransferase conferring tolerance to toxic aromatic amine chemicals: molecular and functional studies M Martins, F Rodrigues-Lima, J Dairou, A Lamouri, F Malagnac, P Silar, ... Journal of biological chemistry 284 (28), 18726-18733, 2009 | 58 | 2009 |
Tumor suppressor role of phospholipase Cε in Ras-triggered cancers M Martins, A McCarthy, R Baxendale, S Guichard, L Magno, N Kessaris, ... Proceedings of the National Academy of Sciences 111 (11), 4239-4244, 2014 | 54 | 2014 |
Cloning and Molecular Characterization of Three Arylamine N-Acetyltransferase Genes from Bacillus anthracis: Identification of Unusual Enzymatic Properties … B Pluvinage, J Dairou, OM Possot, M Martins, A Fouet, JM Dupret, ... Biochemistry 46 (23), 7069-7078, 2007 | 48 | 2007 |
Exploring the cytotoxic activity of new phenanthroline salicylaldimine Zn (II) complexes CP Matos, Y Addis, P Nunes, S Barroso, I Alho, M Martins, APA Matos, ... Journal of Inorganic Biochemistry 198, 110727, 2019 | 41 | 2019 |
Frequent and persistent PLCG1 mutations in Sezary cells directly enhance PLCγ1 activity and stimulate NFκB, AP-1, and NFAT signaling VM Patel, CE Flanagan, M Martins, CL Jones, RM Butler, WJ Woollard, ... Journal of Investigative Dermatology 140 (2), 380-389. e4, 2020 | 29 | 2020 |
Activity of PLCε contributes to chemotaxis of fibroblasts towards PDGF M Martins, S Warren, C Kimberley, A Margineanu, P Peschard, ... Journal of cell science 125 (23), 5758-5769, 2012 | 29 | 2012 |
Functional and structural characterization of the arylamine N-acetyltransferase from the opportunistic pathogen Nocardia farcinica M Martins, B Pluvinage, IL de la Sierra-Gallay, F Barbault, J Dairou, ... Journal of molecular biology 383 (3), 549-560, 2008 | 28 | 2008 |
Insights into the Phylogeny or Arylamine N-Acetyltransferases in Fungi M Martins, J Dairou, F Rodrigues-Lima, JM Dupret, P Silar Journal of molecular evolution 71, 141-152, 2010 | 23 | 2010 |
On the path to gold: Monoanionic Au bisdithiolate complexes with antimicrobial and antitumor activities SA Sousa, JH Leitão, RAL Silva, D Belo, IC Santos, JF Guerreiro, ... Journal of Inorganic Biochemistry 202, 110904, 2020 | 22 | 2020 |
Anti-EGFR therapy to treat metastatic colorectal cancer: not for all M Martins, A Mansinho, R Cruz-Duarte, SL Martins, L Costa Targeted Therapy of Colorectal Cancer Subtypes, 113-131, 2018 | 22 | 2018 |
Pt-Fe ferrocenyl compounds with hydroxyquinoline ligands show selective cytotoxicity on highly proliferative cells F Rivas, A Medeiros, M Comini, L Suescun, ER Arce, M Martins, ... Journal of inorganic biochemistry 199, 110779, 2019 | 21 | 2019 |
Pesticide-derived aromatic amines and their biotransformation JM Dupret, A Cocaign, C Mougin, F Rodrigues-Lima, F Busi, J Dairou, ... INTECH Open Access Publisher, 2011 | 21 | 2011 |
Dynamic allostery in PLCγ1 and Its modulation by a cancer mutation revealed by MD simulation and NMR H Koss, TD Bunney, D Esposito, M Martins, M Katan, PC Driscoll Biophysical journal 115 (1), 31-45, 2018 | 13 | 2018 |
Antitumour and toxicity evaluation of a Ru (II)-cyclopentadienyl complex in a prostate cancer model by imaging tools L Gano, T Pinheiro, AP Matos, F Tortosa, TF Jorge, MS Gonçalves, ... Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2019 | 12 | 2019 |