Chromatin architecture reorganization during stem cell differentiation JR Dixon, I Jung, S Selvaraj, Y Shen, JE Antosiewicz-Bourget, AY Lee, ... Nature 518 (7539), 331-336, 2015 | 1710 | 2015 |
Molecular evolution by staggered extension process (StEP) in vitro recombination H Zhao, L Giver, Z Shao, JA Affholter, FH Arnold Nature biotechnology 16 (3), 258-261, 1998 | 1363 | 1998 |
DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways Z Shao, H Zhao, H Zhao Nucleic acids research 37 (2), e16-e16, 2009 | 809 | 2009 |
High-Efficiency Multiplex Genome Editing of Streptomyces Species Using an Engineered CRISPR/Cas System RE Cobb, Y Wang, H Zhao ACS synthetic biology 4 (6), 723-728, 2015 | 645 | 2015 |
Directed evolution converts subtilisin E into a functional equivalent of thermitase H Zhao, FH Arnold Protein engineering 12 (1), 47-53, 1999 | 479 | 1999 |
Recent developments in pyridine nucleotide regeneration WA Van Der Donk, H Zhao Current Opinion in Biotechnology 14 (4), 421-426, 2003 | 471 | 2003 |
Regeneration of cofactors for use in biocatalysis H Zhao, WA Van Der Donk Current opinion in biotechnology 14 (6), 583-589, 2003 | 447 | 2003 |
A rewritable, random-access DNA-based storage system SM Tabatabaei Yazdi, Y Yuan, J Ma, H Zhao, O Milenkovic Scientific reports 5 (1), 1-10, 2015 | 426 | 2015 |
Homology-Integrated CRISPR–Cas (HI-CRISPR) System for One-Step Multigene Disruption in Saccharomyces cerevisiae Z Bao, H Xiao, J Liang, L Zhang, X Xiong, N Sun, T Si, H Zhao ACS synthetic biology 4 (5), 585-594, 2015 | 420 | 2015 |
Optimization of DNA shuffling for high fidelity recombination H Zhao, FH Arnold Nucleic acids research 25 (6), 1307-1308, 1997 | 415 | 1997 |
Random-priming in vitro recombination: an effective tool for directed evolution Z Shao, H Zhao, L Giver, FH Arnold Nucleic Acids Research 26 (2), 681-683, 1998 | 374 | 1998 |
Transcription activator‐like effector nucleases (TALENs): a highly efficient and versatile tool for genome editing N Sun, H Zhao Biotechnology and bioengineering 110 (7), 1811-1821, 2013 | 327 | 2013 |
Directed evolution: methodologies and applications Y Wang, P Xue, M Cao, T Yu, ST Lane, H Zhao Chemical reviews 121 (20), 12384-12444, 2021 | 316 | 2021 |
Directed evolution of enzymes and biosynthetic pathways TW Johannes, H Zhao Current opinion in microbiology 9 (3), 261-267, 2006 | 306 | 2006 |
Selective elimination of mitochondrial mutations in the germline by genome editing P Reddy, A Ocampo, K Suzuki, J Luo, SR Bacman, SL Williams, ... Cell 161 (3), 459-469, 2015 | 305 | 2015 |
Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering W Zha, SB Rubin-Pitel, Z Shao, H Zhao Metabolic engineering 11 (3), 192-198, 2009 | 304 | 2009 |
Engineering microbial factories for synthesis of value-added products J Du, Z Shao, H Zhao Journal of Industrial Microbiology and Biotechnology 38 (8), 873-890, 2011 | 302 | 2011 |
Combinatorial metabolic engineering using an orthogonal tri-functional CRISPR system J Lian, M HamediRad, S Hu, H Zhao Nature communications 8 (1), 1688, 2017 | 299 | 2017 |
CRISPR–Cas9 strategy for activation of silent Streptomyces biosynthetic gene clusters MM Zhang, FT Wong, Y Wang, S Luo, YH Lim, E Heng, WL Yeo, RE Cobb, ... Nature chemical biology 13 (6), 607-609, 2017 | 297 | 2017 |
Recent advances in metabolic engineering of Saccharomyces cerevisiae: new tools and their applications J Lian, S Mishra, H Zhao Metabolic engineering 50, 85-108, 2018 | 295 | 2018 |