| Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway T Zhang, J Liu, M Fellner, C Zhang, D Sui, J Hu Science advances 3 (8), e1700344, 2017 | 162 | 2017 |
| Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist C Zhang, T Zhang, J Zou, CL Miller, R Gorkhali, JY Yang, A Schilmiller, ... Science advances 2 (5), e1600241, 2016 | 140 | 2016 |
| A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase B Desguin, T Zhang, P Soumillion, P Hols, J Hu, RP Hausinger Science 349 (6243), 66-69, 2015 | 98 | 2015 |
| Structural insights of ZIP4 extracellular domain critical for optimal zinc transport T Zhang, D Sui, J Hu Nature communications 7 (1), 11979, 2016 | 86 | 2016 |
| The crystal structure of GXGD membrane protease FlaK J Hu, Y Xue, S Lee, Y Ha Nature 475 (7357), 528-531, 2011 | 80 | 2011 |
| Structural biology of transmembrane domains: efficient production and characterization of transmembrane peptides by NMR J Hu, H Qin, C Li, M Sharma, TA Cross, FP Gao Protein Science 16 (10), 2153-2165, 2007 | 68 | 2007 |
| Lipid bilayers: an essential environment for the understanding of membrane proteins RC Page, C Li, J Hu, FP Gao, TA Cross Magnetic Resonance in Chemistry 45 (S1), S2-S11, 2007 | 65 | 2007 |
| Structures and mechanisms of the non-heme Fe (II)-and 2-oxoglutarate-dependent ethylene-forming enzyme: substrate binding creates a twist S Martinez, M Fellner, CQ Herr, A Ritchie, J Hu, RP Hausinger Journal of the American Chemical Society 139 (34), 11980-11988, 2017 | 62 | 2017 |
| Construction of a series of vectors for high throughput cloning and expression screening of membrane proteins from Mycobacterium tuberculosis H Qin, J Hu, Y Hua, SV Challa, TA Cross, FP Gao BMC biotechnology 8, 1-8, 2008 | 60 | 2008 |
| Toward unzipping the ZIP metal transporters: structure, evolution, and implications on drug discovery against cancer J Hu The FEBS journal 288 (20), 5805-5825, 2021 | 56 | 2021 |
| Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled J Hu, Q Yuan, X Kang, Y Qin, L Li, Y Ha, D Wu Nature communications 6 (1), 8205, 2015 | 53 | 2015 |
| The E2 domains of APP and APLP1 share a conserved mode of dimerization S Lee, Y Xue, J Hu, Y Wang, X Liu, B Demeler, Y Ha Biochemistry 50 (24), 5453-5464, 2011 | 50 | 2011 |
| A systematic assessment of mature MBP in membrane protein production: overexpression, membrane targeting and purification J Hu, H Qin, FP Gao, TA Cross Protein expression and purification 80 (1), 34-40, 2011 | 48 | 2011 |
| Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and enzymatic function NM Good, M Fellner, K Demirer, J Hu, RP Hausinger, ... Journal of Biological Chemistry 295 (24), 8272-8284, 2020 | 42 | 2020 |
| Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase B Desguin, M Fellner, O Riant, J Hu, RP Hausinger, P Hols, P Soumillion Journal of Biological Chemistry 293 (32), 12303-12317, 2018 | 41 | 2018 |
| Asymmetric functions of a binuclear metal center within the transport pathway of a human zinc transporter ZIP4 T Zhang, D Sui, C Zhang, L Cole, J Hu FASEB journal: official publication of the Federation of American Societies …, 2020 | 40 | 2020 |
| Molecular basis of zinc-dependent endocytosis of human ZIP4 transceptor C Zhang, D Sui, T Zhang, J Hu Cell reports 31 (4), 2020 | 39 | 2020 |
| Cluster learning-assisted directed evolution Y Qiu, J Hu, GW Wei Nature computational science 1 (12), 809-818, 2021 | 38 | 2021 |
| Atomic and Electronic Structure Determinants Distinguish between Ethylene Formation and l-Arginine Hydroxylation Reaction Mechanisms in the Ethylene-Forming … SS Chaturvedi, R Ramanan, J Hu, RP Hausinger, CZ Christov ACS Catalysis 11 (3), 1578-1592, 2021 | 37 | 2021 |
| Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE M Fellner, B Desguin, RP Hausinger, J Hu Proceedings of the National Academy of Sciences 114 (34), 9074-9079, 2017 | 37 | 2017 |
