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Carolyn L. Cummins
Carolyn L. Cummins
Associate Professor, Department Pharmaceutical Sciences, University of Toronto
在 utoronto.ca 的电子邮件经过验证 - 首页
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Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
T Inagaki, M Choi, A Moschetta, L Peng, CL Cummins, JG McDonald, ...
Cell metabolism 2 (4), 217-225, 2005
19692005
Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans
DL Motola, CL Cummins, V Rottiers, KK Sharma, T Li, Y Li, ...
Cell 124 (6), 1209-1223, 2006
5472006
High‐throughput real‐time quantitative reverse transcription PCR
AL Bookout, CL Cummins, DJ Mangelsdorf, JM Pesola, MF Kramer
Current protocols in molecular biology 73 (1), 15.8. 1-15.8. 28, 2006
5012006
High‐throughput real‐time quantitative reverse transcription PCR
AL Bookout, CL Cummins, DJ Mangelsdorf, JM Pesola, MF Kramer
Current protocols in molecular biology 73 (1), 15.8. 1-15.8. 28, 2006
5012006
Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4
CL Cummins, W Jacobsen, LZ Benet
Journal of Pharmacology and Experimental Therapeutics 300 (3), 1036-1045, 2002
4212002
27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen
M Umetani, H Domoto, AK Gormley, IS Yuhanna, CL Cummins, NB Javitt, ...
Nature medicine 13 (10), 1185-1192, 2007
4122007
The drug efflux–metabolism alliance: biochemical aspects
LZ Benet, CL Cummins
Advanced drug delivery reviews 50, S3-S11, 2001
3492001
Unmasking the dynamic interplay between efflux transporters and metabolic enzymes
LZ Benet, CL Cummins, CY Wu
International journal of pharmaceutics 277 (1-2), 3-9, 2004
3412004
Mapping the cellular response to small molecules using chemogenomic fitness signatures
AY Lee, RP St. Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ...
Science 344 (6180), 208-211, 2014
2682014
Mapping the cellular response to small molecules using chemogenomic fitness signatures
AY Lee, RP St. Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ...
Science 344 (6180), 208-211, 2014
2682014
A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling
B Gerisch, V Rottiers, D Li, DL Motola, CL Cummins, H Lehrach, ...
Proceedings of the National Academy of Sciences 104 (12), 5014-5019, 2007
2652007
Transporter-enzyme interactions: implications for predicting drug-drug interactions from in vitro data
LZ Benet, CL Cummins, CY Wu
Current drug metabolism 4 (5), 393-398, 2003
2272003
Sex-related differences in the clearance of cytochrome P450 3A4 substrates may be caused by P-glycoprotein*
CL Cummins, CY Wu, LZ Benet
Clinical Pharmacology & Therapeutics 72 (5), 474-489, 2002
2122002
Hormonal control of C. elegans dauer formation and life span by a Rieske-like oxygenase
V Rottiers, DL Motola, B Gerisch, CL Cummins, K Nishiwaki, ...
Developmental cell 10 (4), 473-482, 2006
2102006
In vivo modulation of intestinal CYP3A metabolism by P-glycoprotein: studies using the rat single-pass intestinal perfusion model
CL Cummins, L Salphati, MJ Reid, LZ Benet
Journal of Pharmacology and Experimental Therapeutics 305 (1), 306-314, 2003
2002003
Liver X receptors regulate adrenal cholesterol balance
CL Cummins, DH Volle, Y Zhang, JG McDonald, B Sion, ...
The Journal of clinical investigation 116 (7), 1902-1912, 2006
1972006
Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis
YK Lee, DR Schmidt, CL Cummins, M Choi, L Peng, Y Zhang, B Goodwin, ...
Molecular Endocrinology 22 (6), 1345-1356, 2008
1832008
Multilayered control of alternative splicing regulatory networks by transcription factors
H Han, U Braunschweig, T Gonatopoulos-Pournatzis, RJ Weatheritt, ...
Molecular Cell 65 (3), 539-553. e7, 2017
1612017
CYP3A4-transfected Caco-2 cells as a tool for understanding biochemical absorption barriers: studies with sirolimus and midazolam
CL Cummins, W Jacobsen, U Christians, LZ Benet
Journal of Pharmacology and Experimental Therapeutics 308 (1), 143-155, 2004
1372004
LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice
R Patel, M Patel, R Tsai, V Lin, AL Bookout, Y Zhang, L Magomedova, T Li, ...
The Journal of clinical investigation 121 (1), 431, 2011
1352011
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