Impact of lipoproteins on the biological activity and disposition of hydrophobic drugs: implications for drug discovery KM Wasan, DR Brocks, SD Lee, K Sachs-Barrable, SJ Thornton Nature Reviews Drug Discovery 7 (1), 84-99, 2008 | 336 | 2008 |
Aster proteins facilitate nonvesicular plasma membrane to ER cholesterol transport in mammalian cells J Sandhu, S Li, L Fairall, SG Pfisterer, JE Gurnett, X Xiao, TA Weston, ... Cell 175 (2), 514-529. e20, 2018 | 219 | 2018 |
Lipid excipients Peceol and Gelucire 44/14 decrease P-glycoprotein mediated efflux of rhodamine 123 partially due to modifying P-glycoprotein protein expression within Caco-2 cells K Sachs-Barrable, A Thamboo, SD Lee, KM Wasan J Pharm Pharm Sci 10 (3), 319-331, 2007 | 176 | 2007 |
Liver X receptors at the intersection of lipid metabolism and atherogenesis SD Lee, P Tontonoz Atherosclerosis 242 (1), 29-36, 2015 | 151 | 2015 |
Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes P Rajbhandari, D Arneson, SK Hart, IS Ahn, G Diamante, LC Santos, ... Elife 8, e49501, 2019 | 137 | 2019 |
Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis A Briot, M Civelek, A Seki, K Hoi, JJ Mack, SD Lee, J Kim, C Hong, J Yu, ... Journal of Experimental Medicine 212 (12), 2147-2163, 2015 | 110 | 2015 |
Enhancing drug absorption using lipids: a case study presenting the development and pharmacological evaluation of a novel lipid-based oral amphotericin B formulation for the … K Sachs-Barrable, SD Lee, EK Wasan, SJ Thornton, KM Wasan Advanced drug delivery reviews 60 (6), 692-701, 2008 | 97 | 2008 |
Long circulating lipid nanocapsules for drug detoxification AB Dhanikula, NM Khalid, SD Lee, R Yeung, V Risovic, KM Wasan, ... Biomaterials 28 (6), 1248-1257, 2007 | 45 | 2007 |
Eosinophils in fat: pink is the new brown SD Lee, P Tontonoz Cell 157 (6), 1249-1250, 2014 | 43 | 2014 |
RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs J Wang, P Rajbhandari, A Damianov, A Han, T Sallam, H Waki, ... The Journal of clinical investigation 127 (3), 987-1004, 2017 | 36 | 2017 |
Dose-dependent targeted suppression of P-glycoprotein expression and function in Caco-2 cells SD Lee, JA Osei-Twum, KM Wasan Molecular pharmaceutics 10 (6), 2323-2330, 2013 | 30 | 2013 |
The Influence of Hyperlipoproteinemia on in Vitro Distribution of Amiodarone and Desethylamiodarone in Human and Rat Plasma A Shayeganpour, SD Lee, KM Wasan, DR Brocks Pharmaceutical research 24, 672-678, 2007 | 29 | 2007 |
Transgenic Expression of Dominant-Active IDOL in Liver Causes Diet-Induced Hypercholesterolemia and Atherosclerosis in Mice AC Calkin, SD Lee, J Kim, CMW Van Stijn, XH Wu, AJ Lusis, C Hong, ... Circulation research 115 (4), 442-449, 2014 | 26 | 2014 |
Effect of dietary fat on hepatic liver X receptor expression in P-glycoprotein deficient mice: implications for cholesterol metabolism SJ Thornton, E Wong, SD Lee, KM Wasan Lipids in Health and Disease 7, 1-7, 2008 | 24 | 2008 |
Inhibition of cholesterol absorption: targeting the intestine SD Lee, P Gershkovich, JW Darlington, KM Wasan Pharmaceutical research 29, 3235-3250, 2012 | 21 | 2012 |
IDOL regulates systemic energy balance through control of neuronal VLDLR expression SD Lee, C Priest, M Bjursell, J Gao, DV Arneson, IS Ahn, G Diamante, ... Nature metabolism 1 (11), 1089-1100, 2019 | 14 | 2019 |
Evaluation of the contribution of the ATP binding cassette transporter, P-glycoprotein, to in vivo cholesterol homeostasis SD Lee, SJ Thornton, K Sachs-Barrable, JH Kim, KM Wasan Molecular pharmaceutics 10 (8), 3203-3212, 2013 | 10 | 2013 |
Influence of Plasma Cholesterol and Triglyceride Concentrations and Eritoran (E5564) Micelle Size on its Plasma Pharmacokinetics and Ex Vivo Activity Following … KM Wasan, V Risovic, O Sivak, SD Lee, DX Mason, GR Chiklis, ... Pharmaceutical research 25, 176-182, 2008 | 9 | 2008 |
Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake A Ferrari, E Whang, X Xiao, JP Kennelly, B Romartinez-Alonso, JJ Mack, ... Science 382 (6671), eadf0966, 2023 | 6 | 2023 |
NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice F Guo, M Seldin, M Péterfy, S Charugundla, Z Zhou, SD Lee, A Mouton, ... Scientific reports 11 (1), 16409, 2021 | 6 | 2021 |