Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production L Lynch, M Nowak, B Varghese, J Clark, AE Hogan, V Toxavidis, SP Balk, ... Immunity 37 (3), 574-587, 2012 | 543 | 2012 |
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses X Michelet, L Dyck, A Hogan, RM Loftus, D Duquette, K Wei, S Beyaz, ... Nature immunology 19 (12), 1330-1340, 2018 | 493 | 2018 |
Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus AE Hogan, G Gaoatswe, L Lynch, MA Corrigan, C Woods, J O’Connell, ... Diabetologia 57, 781-784, 2014 | 208 | 2014 |
Adipose type one innate lymphoid cells regulate macrophage homeostasis through targeted cytotoxicity S Boulenouar, X Michelet, D Duquette, D Alvarez, AE Hogan, C Dold, ... Immunity 46 (2), 273-286, 2017 | 195 | 2017 |
iNKT cells induce FGF21 for thermogenesis and are required for maximal weight loss in GLP1 therapy L Lynch, AE Hogan, D Duquette, C Lester, A Banks, K LeClair, DE Cohen, ... Cell metabolism 24 (3), 510-519, 2016 | 181 | 2016 |
Cutting edge: CD1d restriction and Th1/Th2/Th17 cytokine secretion by human Vδ3 T cells BA Mangan, MR Dunne, VP O’Reilly, PJ Dunne, MA Exley, D O’Shea, ... The Journal of Immunology 191 (1), 30-34, 2013 | 181 | 2013 |
Altered distribution and increased IL-17 production by mucosal-associated invariant T cells in adult and childhood obesity E Carolan, LM Tobin, BA Mangan, M Corrigan, G Gaoatswe, G Byrne, ... The Journal of Immunology 194 (12), 5775-5780, 2015 | 180 | 2015 |
Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis AE Hogan, AM Tobin, T Ahern, MA Corrigan, G Gaoatswe, R Jackson, ... Diabetologia 54, 2745-2754, 2011 | 180 | 2011 |
Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer AJ Michielsen, AE Hogan, J Marry, M Tosetto, F Cox, JM Hyland, ... PloS one 6 (11), e27944, 2011 | 160 | 2011 |
Distinct and Overlapping Effector Functions of Expanded Human CD4+, CD8α+ and CD4-CD8α-Invariant Natural Killer T Cells V O'Reilly, SG Zeng, G Bricard, A Atzberger, AE Hogan, J Jackson, ... PloS one 6 (12), e28648, 2011 | 124 | 2011 |
NK cells in childhood obesity are activated, metabolically stressed, and functionally deficient LM Tobin, M Mavinkurve, E Carolan, D Kinlen, EC O’Brien, MA Little, ... JCI insight 2 (24), 2017 | 112 | 2017 |
The impact of childhood obesity on inflammation, innate immune cell frequency, and metabolic microRNA expression E Carolan, AE Hogan, M Corrigan, G Gaotswe, J O'Connell, N Foley, ... The Journal of Clinical Endocrinology & Metabolism 99 (3), E474-E478, 2014 | 112 | 2014 |
Dysregulation of natural killer cells in obesity D O’Shea, AE Hogan Cancers 11 (4), 573, 2019 | 107 | 2019 |
Preadipocyte Factor-1 is associated with metabolic profile in severe obesity J O'Connell, L Lynch, A Hogan, TJ Cawood, D O'Shea Journal of Clinical Endocrinology & Metabolism 96 (4), E680-E684, 2011 | 89 | 2011 |
Changes in human dendritic cell number and function in severe obesity may contribute to increased susceptibility to viral infection D O'Shea, M Corrigan, MR Dunne, R Jackson, C Woods, G Gaoatswe, ... International journal of obesity 37 (11), 1510-1513, 2013 | 88 | 2013 |
The helminth T2 RNase ω1 promotes metabolic homeostasis in an IL-33–and group 2 innate lymphoid cell–dependent mechanism E Hams, R Bermingham, FA Wurlod, AE Hogan, D O’Shea, RJ Preston, ... The FASEB Journal 30 (2), 824, 2016 | 80 | 2016 |
Glucagon‐like peptide‐1 analogue therapy for psoriasis patients with obesity and type 2 diabetes: a prospective cohort study T Ahern, AM Tobin, M Corrigan, A Hogan, C Sweeney, B Kirby, D O’Shea Journal of the European Academy of Dermatology and Venereology 27 (11), 1440 …, 2013 | 72 | 2013 |
Lymphocyte roles in metabolic dysfunction: of men and mice BC Ip, AE Hogan, BS Nikolajczyk Trends in Endocrinology & Metabolism 26 (2), 91-100, 2015 | 65 | 2015 |
Obesity reduces mTORC1 activity in mucosal-associated invariant T cells, driving defective metabolic and functional responses A O’Brien, RM Loftus, MM Pisarska, LM Tobin, R Bergin, NAW Wood, ... The Journal of Immunology 202 (12), 3404-3411, 2019 | 64 | 2019 |
Suppressive effects of the obese tumor microenvironment on CD8 T cell infiltration and effector function L Dyck, H Prendeville, M Raverdeau, MM Wilk, RM Loftus, A Douglas, ... Journal of Experimental Medicine 219 (3), 2022 | 60 | 2022 |