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Hitesh S Purohit
Hitesh S Purohit
AbbVie Inc, Purdue University, NIPER
在 abbvie.com 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Phase separation kinetics in amorphous solid dispersions upon exposure to water
HS Purohit, LS Taylor
Molecular pharmaceutics 12 (5), 1623-1635, 2015
1062015
Phase behavior of ritonavir amorphous solid dispersions during hydration and dissolution
HS Purohit, LS Taylor
Pharmaceutical research 34, 2842-2861, 2017
1032017
Novel lipid based oral formulation of curcumin: development and optimization by design of experiments approach
YB Pawar, H Purohit, GR Valicherla, B Munjal, SV Lale, SB Patel, ...
International journal of pharmaceutics 436 (1-2), 617-623, 2012
822012
Miscibility of itraconazole–hydroxypropyl methylcellulose blends: Insights with high resolution analytical methodologies
HS Purohit, LS Taylor
Molecular pharmaceutics 12 (12), 4542-4553, 2015
702015
Investigating the impact of drug crystallinity in amorphous tacrolimus capsules on pharmacokinetics and bioequivalence using discriminatory in vitro dissolution testing and …
HS Purohit, NS Trasi, DD Sun, ECY Chow, H Wen, X Zhang, Y Gao, ...
Journal of pharmaceutical sciences 107 (5), 1330-1341, 2018
662018
Insights into nano-and micron-scale phase separation in amorphous solid dispersions using fluorescence-based techniques in combination with solid state nuclear magnetic …
HS Purohit, JD Ormes, S Saboo, Y Su, MS Lamm, AKP Mann, LS Taylor
Pharmaceutical research 34, 1364-1377, 2017
652017
Dropwise additive manufacturing of pharmaceutical products for amorphous and self emulsifying drug delivery systems
E Içten, HS Purohit, C Wallace, A Giridhar, LS Taylor, ZK Nagy, ...
International journal of pharmaceutics 524 (1-2), 424-432, 2017
522017
Evaluation of the crystallization tendency of commercially available amorphous tacrolimus formulations exposed to different stress conditions
NS Trasi, HS Purohit, LS Taylor
Pharmaceutical research 34, 2142-2155, 2017
412017
Non-Sink Dissolution Behavior and Solubility Limit of Commercial Tacrolimus Amorphous Formulations
NS Trasi, HS Purohit, H Wen, DD Sun, LS Taylor
Journal of Pharmaceutical Sciences 106 (1), 264-272, 2017
342017
Assessing the impact of endogenously derived crystalline drug on the in vivo performance of amorphous formulations
HS Purohit, NS Trasi, DJ Osterling, DF Stolarik, GJ Jenkins, W Gao, ...
Molecular pharmaceutics 16 (8), 3617-3625, 2019
302019
Release mechanisms of amorphous solid dispersions: role of drug-polymer phase separation and morphology
R Yang, GGZ Zhang, DY Zemlyanov, HS Purohit, LS Taylor
Journal of Pharmaceutical Sciences 112 (1), 304-317, 2023
242023
Phase separation in surfactant-containing amorphous solid dispersions: Orthogonal analytical methods to probe the effects of surfactants on morphology and phase composition
R Yang, GGZ Zhang, K Kjoller, E Dillon, HS Purohit, LS Taylor
International Journal of Pharmaceutics 619, 121708, 2022
192022
Dissolution Mechanisms of Amorphous Solid Dispersions: Role of Drug Load and Molecular Interactions
A Deac, Q Qi, AS Indulkar, HS Purohit, Y Gao, GGZ Zhang, LS Taylor
Molecular Pharmaceutics 20 (1), 722-737, 2022
182022
Drug Release from Surfactant-Containing Amorphous Solid Dispersions: Mechanism and Role of Surfactant in Release Enhancement
R Yang, GGZ Zhang, DY Zemlyanov, HS Purohit, LS Taylor
Pharmaceutical Research, 1-29, 2023
72023
Detecting Crystallinity in Amorphous Solid Dispersions Using Dissolution Testing: Considerations on Properties of Drug Substance, Drug Product, and Selection of Dissolution Media
HS Purohit, GGZ Zhang, Y Gao
Journal of Pharmaceutical Sciences 112 (1), 290-303, 2023
52023
Design of a Re-Dispersible High Drug Load Amorphous Formulation
HS Oberoi, F Arce, HS Purohit, M Yu, CA Fowler, D Zhou, D Law
Journal of Pharmaceutical Sciences 112 (1), 250-263, 2023
32023
Proof-of-concept in developing a 45% drug loaded amorphous nanoparticle formulation
HS Purohit, D Zhou, M Yu, M Zaroudi, H Oberoi, ALR López, MS Kelkar, ...
Journal of Pharmaceutical Sciences, 2023
22023
Phase Behavior of Amorphous Solid Dispersions during Hydration and Dissolution
HS Purohit
Purdue University, 2017
12017
Design of Redispersible High-Drug-Load Amorphous Formulations: Impact of Ionic vs Nonionic Surfactants on Processing and Performance
M Yu, HS Oberoi, HS Purohit, CA Fowler, D Law
Molecular Pharmaceutics, 2023
2023
Limitations in the Pharmacopeial Dissolution Testing of Marketed Tacrolimus Amorphous Solid Dispersions
HS Purohit, Y Gao, GG Zhang, D Sun, H Wen, LS Taylor
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