| Role of uric acid metabolism‐related inflammation in the pathogenesis of metabolic syndrome components such as atherosclerosis and nonalcoholic steatohepatitis A Kushiyama, Y Nakatsu, Y Matsunaga, T Yamamotoya, K Mori, K Ueda, ... Mediators of inflammation 2016 (1), 8603164, 2016 | 161 | 2016 |
| Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus S Qiang, Y Nakatsu, Y Seno, M Fujishiro, H Sakoda, A Kushiyama, K Mori, ... Diabetology & metabolic syndrome 7, 1-7, 2015 | 130 | 2015 |
| The SGLT2 inhibitor luseogliflozin rapidly normalizes aortic mRNA levels of inflammation-related but not lipid-metabolism-related genes and suppresses atherosclerosis in … Y Nakatsu, H Kokubo, B Bumdelger, M Yoshizumi, T Yamamotoya, ... International journal of molecular sciences 18 (8), 1704, 2017 | 83 | 2017 |
| The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model Y Nakatsu, Y Seno, A Kushiyama, H Sakoda, M Fujishiro, A Katasako, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 309 (1 …, 2015 | 74 | 2015 |
| Protective Effect of Sex Hormone‐Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti‐Inflammatory and Lipolytic Effects on Adipocytes … H Yamazaki, A Kushiyama, H Sakoda, M Fujishiro, T Yamamotoya, ... Mediators of inflammation 2018 (1), 3062319, 2018 | 73 | 2018 |
| Gut microbiota as a therapeutic target for metabolic disorders H Okubo, Y Nakatsu, A Kushiyama, T Yamamotoya, Y Matsunaga, ... Current medicinal chemistry 25 (9), 984-1001, 2018 | 68 | 2018 |
| Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice MK Inoue, Y Matsunaga, Y Nakatsu, T Yamamotoya, K Ueda, ... Diabetology & metabolic syndrome 11, 1-11, 2019 | 55 | 2019 |
| Physiological and pathogenic roles of prolyl isomerase Pin1 in metabolic regulations via multiple signal transduction pathway modulations Y Nakatsu, Y Matsunaga, T Yamamotoya, K Ueda, Y Inoue, K Mori, ... International Journal of Molecular Sciences 17 (9), 1495, 2016 | 47 | 2016 |
| Gastrointestinal symptom prevalence depends on disease duration and gastrointestinal region in type 2 diabetes mellitus M Fujishiro, A Kushiyama, H Yamazaki, S Kaneko, Y Koketsu, ... World journal of gastroenterology 23 (36), 6694, 2017 | 36 | 2017 |
| Xanthine oxidase inhibitor febuxostat exerts an anti-inflammatory action and protects against diabetic nephropathy development in KK-Ay obese diabetic mice Y Mizuno, T Yamamotoya, Y Nakatsu, K Ueda, Y Matsunaga, MK Inoue, ... International Journal of Molecular Sciences 20 (19), 4680, 2019 | 35 | 2019 |
| Prolyl isomerase Pin1 in metabolic reprogramming of cancer cells Y Nakatsu, T Yamamotoya, K Ueda, H Ono, MK Inoue, Y Matsunaga, ... Cancer letters 470, 106-114, 2020 | 34 | 2020 |
| Pin1 inhibitor juglone exerts anti-oncogenic effects on LNCaP and DU145 cells despite the patterns of gene regulation by Pin1 differing between these cell lines R Kanaoka, A Kushiyama, Y Seno, Y Nakatsu, Y Matsunaga, ... PLoS One 10 (6), e0127467, 2015 | 31 | 2015 |
| Carnosic acid and carnosol activate AMPK, suppress expressions of gluconeogenic and lipogenic genes, and inhibit proliferation of HepG2 cells S Hasei, T Yamamotoya, Y Nakatsu, Y Ohata, S Itoga, Y Nonaka, ... International journal of molecular sciences 22 (8), 4040, 2021 | 25 | 2021 |
| Roles of gut-derived secretory factors in the pathogenesis of non-alcoholic fatty liver disease and their possible clinical applications H Okubo, A Kushiyama, Y Nakatsu, T Yamamotoya, Y Matsunaga, ... International Journal of Molecular Sciences 19 (10), 3064, 2018 | 25 | 2018 |
| Prolyl isomerase Pin1 binds to and stabilizes acetyl CoA carboxylase 1 protein, thereby supporting cancer cell proliferation K Ueda, Y Nakatsu, T Yamamotoya, H Ono, Y Inoue, MK Inoue, Y Mizuno, ... Oncotarget 10 (17), 1637, 2019 | 24 | 2019 |
| The prolyl isomerase Pin1 increases β-cell proliferation and enhances insulin secretion Y Nakatsu, K Mori, Y Matsunaga, T Yamamotoya, K Ueda, Y Inoue, ... Journal of Biological Chemistry 292 (28), 11886-11895, 2017 | 24 | 2017 |
| Par14 protein associates with insulin receptor substrate 1 (IRS-1), thereby enhancing insulin-induced IRS-1 phosphorylation and metabolic actions J Zhang, Y Nakatsu, T Shinjo, Y Guo, H Sakoda, T Yamamotoya, Y Otani, ... Journal of Biological Chemistry 288 (28), 20692-20701, 2013 | 22 | 2013 |
| Prolyl isomerase Pin1 suppresses thermogenic programs in adipocytes by promoting degradation of transcriptional co-activator PRDM16 Y Nakatsu, Y Matsunaga, T Yamamotoya, K Ueda, M Inoue, Y Mizuno, ... Cell Reports 26 (12), 3221-3230. e3, 2019 | 21 | 2019 |
| The xanthine oxidase inhibitor febuxostat suppresses the progression of IgA nephropathy, possibly via its anti-inflammatory and anti-fibrotic effects in the gddY mouse model MK Inoue, T Yamamotoya, Y Nakatsu, K Ueda, Y Inoue, Y Matsunaga, ... International Journal of Molecular Sciences 19 (12), 3967, 2018 | 21 | 2018 |
| Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity T Yamamotoya, Y Nakatsu, A Kushiyama, Y Matsunaga, K Ueda, Y Inoue, ... Scientific reports 7 (1), 13026, 2017 | 20 | 2017 |
