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Mikah Brandes
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NRF2 as a Therapeutic Target in Neurodegenerative Diseases
MS Brandes, NE Gray
ASN neuro 12, 1759091419899782, 2020
1952020
Loss of NRF2 leads to impaired mitochondrial function, decreased synaptic density and exacerbated age-related cognitive deficits
JA Zweig, M Caruso, MS Brandes, NE Gray
Experimental Gerontology 131, 110767, 2020
372020
Prolonged Treatment with Centella asiatica Improves Memory, Reduces Amyloid-β Pathology, and Activates NRF2-Regulated Antioxidant Response Pathway in 5xFAD Mice
JA Zweig, MS Brandes, BH Brumbach, M Caruso, KM Wright, JF Quinn, ...
Journal of Alzheimer's Disease, 1-16, 2021
212021
Loss of NRF2 accelerates cognitive decline, exacerbates mitochondrial dysfunction and is required for the cognitive enhancing effects of Centella asiatica during aging.
NE Zweig, Jonathan A., Brandes, Mikah S., Brumbach, Barbara H., Caruso, Maya ...
Neurobiology of Aging, 2020
20*2020
Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella asiatica Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized …
KM Wright, M Bollen, J David, AB Speers, MS Brandes, NE Gray, ...
Antioxidants 11 (2), 215, 2022
182022
NRF2 Activation Ameliorates Oxidative Stress and Improves Mitochondrial Function and Synaptic Plasticity, and in A53T α-Synuclein Hippocampal Neurons
MS Brandes, JA Zweig, A Tang, NE Gray
Antioxidants 11 (1), 26, 2022
162022
Investigating the effects of centella asiatica on neuroinflammation in beta‐amyloid overexpressing mice
AB Speers, MS Brandes, NE Kedjejian, DG Matthews, M Caruso, ...
Alzheimer's & Dementia 19, e064289, 2023
12023
Centella asiatica promotes antioxidant gene expression and mitochondrial oxidative respiration in experimental autoimmune encephalomyelitis
P Kundu, K Yasuhara, MS Brandes, JA Zweig, CJ Neff, S Holden, ...
2023
Asiatic improves brain mitochondrial function, activates antioxidant response and attenuates cognitive deficits in beta amyloid overexpressing mice
NE Gray, SR Chamberlin, LE Bui, MS Brandes, BH Brumbach, JF Quinn
Alzheimer's & Dementia 19, e062432, 2023
2023
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