| Strategies to target SARS-CoV-2 entry and infection using dual mechanisms of inhibition by acidification inhibitors C Prabhakara, R Godbole, P Sil, S Jahnavi, SJ Gulzar, TS van Zanten, ... PLoS pathogens 17 (7), e1009706, 2021 | 55 | 2021 |
| Discovery of Helminthosporin, an Anthraquinone Isolated from Rumex abyssinicus Jacq as a Dual Cholinesterase Inhibitor N Augustin, VK Nuthakki, M Abdullaha, QP Hassan, SG Gandhi, ... ACS omega 5 (3), 1616-1624, 2020 | 55 | 2020 |
| Identification of embelin, a 3‐undecyl‐1,4‐benzoquinone from Embelia ribes as a multitargeted anti‐Alzheimer agent VK Nuthakki, A Sharma, A Kumar, SB Bharate Drug Development Research 80 (5), 655-665, 2019 | 48 | 2019 |
| Discovery and preclinical development of IIIM-290, an orally active potent cyclin-dependent kinase inhibitor SB Bharate, V Kumar, SK Jain, MJ Mintoo, SK Guru, VK Nuthakki, ... Journal of medicinal chemistry 61 (4), 1664-1687, 2018 | 47 | 2018 |
| Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors VK Nuthakki, R Mudududdla, A Sharma, A Kumar, SB Bharate Bioorganic Chemistry 90, 103062, 2019 | 40 | 2019 |
| Discovery of methoxy-naphthyl linked N-(1-benzylpiperidine) benzamide as a blood-brain permeable dual inhibitor of acetylcholinesterase and butyrylcholinesterase M Abdullaha, VK Nuthakki, SB Bharate European Journal of Medicinal Chemistry 207, 112761, 2020 | 26 | 2020 |
| Quantitative phytochemical estimation and evaluation of hepatoprotective activity of methanolic extract of Dendrobium ovatum (L.) Kraenzl. Whole plant against CCl4 induced … S Ganapaty, M Ramaiah, K Yasaswini, VK Nuthakki, D Harikrishnareddy Journal of Pharmacognosy and Phytochemistry 2 (3), 113-118, 2013 | 24 | 2013 |
| Design, synthesis, and pharmacological evaluation of embelin–aryl/alkyl amine hybrids as orally bioavailable blood–brain barrier permeable multitargeted agents with therapeutic … VK Nuthakki, S Choudhary, CN Reddy, S Bhatt, A Jamwal, A Jotshi, ... ACS chemical neuroscience 14 (6), 1193-1219, 2023 | 14 | 2023 |
| Identification of aplysinopsin as a blood-brain barrier permeable scaffold for anti-cholinesterase and anti-BACE-1 activity VK Nuthakki, RRY Bheemanaboina, SB Bharate Bioorganic Chemistry 107, 104568, 2021 | 14 | 2021 |
| Malononitrile-activated synthesis and anti-cholinesterase activity of styrylquinoxalin-2 (1 H)-ones S Mahajan, N Slathia, VK Nuthakki, SB Bharate, KK Kapoor RSC advances 10 (27), 15966-15975, 2020 | 14 | 2020 |
| Biotransformation of chrysin to baicalein: selective C6-hydroxylation of 5, 7-dihydroxyflavone using whole yeast cells stably expressing human CYP1A1 enzyme IS Williams, S Chib, VK Nuthakki, L Gatchie, P Joshi, NA Narkhede, ... Journal of agricultural and food chemistry 65 (34), 7440-7446, 2017 | 14 | 2017 |
| Role of basic aminoalkyl chains in the lead optimization of Indoloquinoline alkaloids VK Nuthakki, R Mudududdla, SB Bharate European Journal of Medicinal Chemistry 227, 113938, 2022 | 10 | 2022 |
| Identification of plant-based multitargeted leads for Alzheimer's disease: In-vitro and in-vivo validation of Woodfordia fruticosa (L.) Kurz R Raghuvanshi, VK Nuthakki, L Singh, B Singh, SS Bharate, R Bhatti, ... Phytomedicine 91, 153659, 2021 | 10 | 2021 |
| Design, synthesis, and structure–activity relationship of caffeine‐based triazoles as dual AChE and BACE‐1 inhibitors M Sharma, A Sharma, VK Nuthakki, S Bhatt, U Nandi, SB Bharate Drug Development Research 83 (8), 1803-1821, 2022 | 9 | 2022 |
| Niclosamide inhibits SARS-CoV2 entry by blocking internalization through pH-dependent CLIC/GEEC endocytic pathway C Prabhakara, R Godbole, P Sil, S Jahnavi, TS van Zanten, D Sheth, ... bioRxiv, 2020.12. 16.422529, 2020 | 8 | 2020 |
| Niclosamide inhibits SARS-CoV2 entry by blocking internalization through pH-dependent CLIC C Prabhakara, R Godbole, P Sil, S Jahnavi, TS van Zanten, D Sheth, ... GEEC endocytic pathway. bioRxiv 2020 (16.422529), 2020 | 7 | 2020 |
| A Coumarin− Donepezil Hybrid as a Blood− Brain Barrier Permeable Dual Cholinesterase Inhibitor: Isolation, Synthetic Modifications, and Biological Evaluation of Natural Coumarins A Sharma, VK Nuthakki, S Gairola, B Singh, SB Bharate ChemMedChem 17 (18), e202200300, 2022 | 6 | 2022 |
| Discovery of blood-brain barrier permeable and orally bioavailable caffeine-based amide derivatives as acetylcholinesterase inhibitors M Sharma, A Sharma, S Thakur, VK Nuthakki, A Jamwal, U Nandi, ... Bioorganic Chemistry 139, 106719, 2023 | 4 | 2023 |
| Blood–brain barrier permeable benzylpiperidin‐4‐yl‐linked benzylamino benzamides as dual cholinesterase inhibitors R Banoo, VK Nuthakki, M Abdullaha, M Sharma, SB Bharate Drug Development Research 83 (8), 1791-1802, 2022 | 4 | 2022 |
| In-vivo evaluation of antidiarrhoeal activity of ethanolic extract of Uraria lagopoides (L.). KR Kumar, VK Nuthakki | 3 | 2014 |
