Macrophage PTEN regulates expression and secretion of arginase I modulating innate and adaptive immune responses E Sahin, S Haubenwallner, M Kuttke, I Kollmann, A Halfmann, AB Dohnal, ... The Journal of Immunology 193 (4), 1717-1727, 2014 | 145 | 2014 |
A non-canonical tricarboxylic acid cycle underlies cellular identity PK Arnold, BT Jackson, KI Paras, JS Brunner, ML Hart, OJ Newsom, ... Nature 603 (7901), 477-481, 2022 | 144 | 2022 |
Sustained PI3K Activation exacerbates BLM-induced Lung Fibrosis via activation of pro-inflammatory and pro-fibrotic pathways JB Kral, M Kuttke, WC Schrottmaier, B Birnecker, J Warszawska, C Wernig, ... Scientific reports 6 (1), 23034, 2016 | 85 | 2016 |
Type I interferon signaling disrupts the hepatic urea cycle and alters systemic metabolism to suppress T cell function A Lercher, A Bhattacharya, AM Popa, M Caldera, MF Schlapansky, ... Immunity 51 (6), 1074-1087. e9, 2019 | 81 | 2019 |
The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia O Sharif, R Gawish, JM Warszawska, R Martins, K Lakovits, A Hladik, ... PLoS pathogens 10 (6), e1004167, 2014 | 80 | 2014 |
Non-classical monocytes as mediators of tissue destruction in arthritis A Puchner, V Saferding, M Bonelli, Y Mikami, M Hofmann, JS Brunner, ... Annals of the rheumatic diseases 77 (10), 1490-1497, 2018 | 64 | 2018 |
MicroRNA-146a governs fibroblast activation and joint pathology in arthritis V Saferding, A Puchner, E Goncalves-Alves, M Hofmann, M Bonelli, ... Journal of autoimmunity 82, 74-84, 2017 | 49 | 2017 |
Environmental arginine controls multinuclear giant cell metabolism and formation JS Brunner, L Vulliard, M Hofmann, M Kieler, A Lercher, A Vogel, ... Nature communications 11 (1), 431, 2020 | 46 | 2020 |
Macrophage rewiring by nutrient associated PI3K dependent pathways O Sharif, JS Brunner, A Vogel, G Schabbauer Frontiers in Immunology 10, 2002, 2019 | 42 | 2019 |
Beneficial metabolic effects of TREM2 in obesity are uncoupled from its expression on macrophages O Sharif, JS Brunner, A Korosec, R Martins, A Jais, B Snijder, A Vogel, ... Diabetes 70 (9), 2042-2057, 2021 | 36 | 2021 |
Phosphatase and tensin homolog (PTEN) in antigen-presenting cells controls Th17-mediated autoimmune arthritis S Blüml, E Sahin, V Saferding, E Goncalves-Alves, E Hainzl, ... Arthritis research & therapy 17, 1-11, 2015 | 34 | 2015 |
MicroRNA-155 controls T helper cell activation during viral infection E Goncalves-Alves, V Saferding, C Schliehe, R Benson, ... Frontiers in Immunology 10, 1367, 2019 | 31 | 2019 |
The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages JS Brunner, A Vogel, A Lercher, M Caldera, A Korosec, M Puehringer, ... Nature Metabolism 2 (12), 1427-1442, 2020 | 30 | 2020 |
Adipocyte-specific deletion of IL-6 does not attenuate obesity-induced weight gain or glucose intolerance in mice M Whitham, M Pal, T Petzold, M Hjorth, CL Egan, JS Brunner, E Estevez, ... American Journal of Physiology-Endocrinology and Metabolism 317 (4), E597-E604, 2019 | 29 | 2019 |
Loss of phosphatase and tensin homolog (PTEN) in myeloid cells controls inflammatory bone destruction by regulating the osteoclastogenic potential of myeloid cells S Blüml, M Friedrich, T Lohmeyer, E Sahin, V Saferding, J Brunner, ... Annals of the rheumatic diseases 74 (1), 227-233, 2015 | 29 | 2015 |
Loss of phosphatase and tensin homolog (PTEN) in myeloid cells controls inflammatory bone destruction by regulating the osteoclastogenic potential of myeloid cells S Bluml, M Friedrich, T Lohmeyer, E Sahin, V Saferding, J Brunner, ... Annals of the rheumatic diseases 74 (1), 227, 2015 | 28 | 2015 |
Lipid scavenging macrophages and inflammation A Vogel, JS Brunner, A Hajto, O Sharif, G Schabbauer Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2022 | 26 | 2022 |
Metabolic determinants of tumour initiation JS Brunner, LWS Finley Nature Reviews Endocrinology 19 (3), 134-150, 2023 | 25 | 2023 |
microRNA‐146a controls age‐related bone loss V Saferding, M Hofmann, JS Brunner, B Niederreiter, M Timmen, ... Aging cell 19 (11), e13244, 2020 | 23 | 2020 |
JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction A Vogel, K Martin, K Soukup, A Halfmann, M Kerndl, JS Brunner, ... Cell Reports 38 (8), 2022 | 21 | 2022 |