Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism SB Prusiner, AL Woerman, DA Mordes, JC Watts, R Rampersaud, ... Proceedings of the National Academy of Sciences 112 (38), E5308-E5317, 2015 | 745 | 2015 |
TopBP1 activates ATR through ATRIP and a PIKK regulatory domain DA Mordes, GG Glick, R Zhao, D Cortez Genes & development 22 (11), 1478-1489, 2008 | 435 | 2008 |
ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair JR Klim, LA Williams, F Limone, I Guerra San Juan, BN Davis-Dusenbery, ... Nature neuroscience 22 (2), 167-179, 2019 | 433 | 2019 |
Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease A Burberry, N Suzuki, JY Wang, R Moccia, DA Mordes, MH Stewart, ... Science translational medicine 8 (347), 347ra93-347ra93, 2016 | 291 | 2016 |
Propagation of prions causing synucleinopathies in cultured cells AL Woerman, J Stöhr, A Aoyagi, R Rampersaud, Z Krejciova, JC Watts, ... Proceedings of the National Academy of Sciences 112 (35), E4949-E4958, 2015 | 247 | 2015 |
The basic cleft of RPA70N binds multiple checkpoint proteins, including RAD9, to regulate ATR signaling X Xu, S Vaithiyalingam, GG Glick, DA Mordes, WJ Chazin, D Cortez Molecular and cellular biology 28 (24), 7345-7353, 2008 | 199 | 2008 |
Function of a conserved checkpoint recruitment domain in ATRIP proteins HL Ball, MR Ehrhardt, DA Mordes, GG Glick, WJ Chazin, D Cortez Molecular and cellular biology 27 (9), 3367-3377, 2007 | 193 | 2007 |
Pre-mRNA splicing and retinitis pigmentosa D Mordes, X Luo, A Kar, D Kuo, L Xu, K Fushimi, G Yu, P Sternberg Jr, ... Molecular vision 12, 1259, 2006 | 168 | 2006 |
Dpb11 activates the Mec1–Ddc2 complex DA Mordes, EA Nam, D Cortez Proceedings of the National Academy of Sciences 105 (48), 18730-18734, 2008 | 166 | 2008 |
Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage SJ Hill, DA Mordes, LA Cameron, DS Neuberg, S Landini, K Eggan, ... Proceedings of the National Academy of Sciences 113 (48), E7701-E7709, 2016 | 142 | 2016 |
Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein SMK Farhan, DP Howrigan, LE Abbott, JR Klim, SD Topp, AE Byrnes, ... Nature neuroscience 22 (12), 1966-1974, 2019 | 116 | 2019 |
Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging F Tian, W Yang, DA Mordes, JY Wang, JS Salameh, J Mok, J Chew, ... Nature communications 7 (1), 1-15, 2016 | 103 | 2016 |
Activation of ATR and related PIKKs DA Mordes, D Cortez Cell Cycle 7 (18), 2809-2812, 2008 | 97 | 2008 |
Identification of neurotoxic cytokines by profiling Alzheimer’s disease tissues and neuron culture viability screening LB Wood, AR Winslow, EA Proctor, D McGuone, DA Mordes, MP Frosch, ... Scientific reports 5 (1), 16622, 2015 | 85 | 2015 |
MSA prions exhibit remarkable stability and resistance to inactivation AL Woerman, SA Kazmi, S Patel, Y Freyman, A Oehler, A Aoyagi, ... Acta neuropathologica 135 (1), 49-63, 2018 | 84 | 2018 |
The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis Y Zhang, A Burberry, JY Wang, J Sandoe, S Ghosh, ND Udeshi, ... Genes & development 32 (13-14), 929-943, 2018 | 78 | 2018 |
Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines AL Woerman, A Oehler, SA Kazmi, J Lee, GM Halliday, LT Middleton, ... Acta neuropathologica 137, 437-454, 2019 | 75 | 2019 |
Identification of photoreceptor genes affected by PRPF31 mutations associated with autosomal dominant retinitis pigmentosa D Mordes, L Yuan, L Xu, M Kawada, RS Molday, JY Wu Neurobiology of disease 26 (2), 291-300, 2007 | 48 | 2007 |
Absence of survival and motor deficits in 500 repeat C9ORF72 BAC mice DA Mordes, BM Morrison, XH Ament, C Cantrell, J Mok, P Eggan, C Xue, ... Neuron 108 (4), 775-783. e4, 2020 | 47 | 2020 |
Familial Parkinson’s point mutation abolishes multiple system atrophy prion replication AL Woerman, SA Kazmi, S Patel, A Aoyagi, A Oehler, K Widjaja, ... Proceedings of the National Academy of Sciences 115 (2), 409-414, 2018 | 40 | 2018 |