Drug–polymer solubility and miscibility: stability consideration and practical challenges in amorphous solid dispersion development F Qian, J Huang, MA Hussain Journal of pharmaceutical sciences 99 (7), 2941-2947, 2010 | 501 | 2010 |
Drug delivery devices and methods J Gao, F Qian, A Exner, J Haaga US Patent App. 10/265,355, 2003 | 207 | 2003 |
Is a distinctive single Tg a reliable indicator for the homogeneity of amorphous solid dispersion? F Qian, J Huang, Q Zhu, R Haddadin, J Gawel, R Garmise, M Hussain International journal of pharmaceutics 395 (1-2), 232-235, 2010 | 174 | 2010 |
Drug–polymer–water interaction and its implication for the dissolution performance of amorphous solid dispersions Y Chen, C Liu, Z Chen, C Su, M Hageman, M Hussain, R Haskell, ... Molecular pharmaceutics 12 (2), 576-589, 2015 | 161 | 2015 |
Improving oral bioavailability of sorafenib by optimizing the “spring” and “parachute” based on molecular interaction mechanisms C Liu, Z Chen, Y Chen, J Lu, Y Li, S Wang, G Wu, F Qian Molecular pharmaceutics 13 (2), 599-608, 2016 | 153 | 2016 |
Intranasal and oral vaccination with protein-based antigens: advantages, challenges and formulation strategies S Wang, H Liu, X Zhang, F Qian Protein & cell 6 (7), 480-503, 2015 | 148 | 2015 |
Enhancement of oral bioavailability of an HIV-attachment inhibitor by nanosizing and amorphous formulation approaches MG Fakes, BJ Vakkalagadda, F Qian, S Desikan, RB Gandhi, C Lai, ... International journal of pharmaceutics 370 (1-2), 167-174, 2009 | 125 | 2009 |
Initial drug dissolution from amorphous solid dispersions controlled by polymer dissolution and drug-polymer interaction Y Chen, S Wang, S Wang, C Liu, C Su, M Hageman, M Hussain, ... Pharmaceutical research 33, 2445-2458, 2016 | 117 | 2016 |
Solution behavior of PVP-VA and HPMC-AS-based amorphous solid dispersions and their bioavailability implications F Qian, J Wang, R Hartley, J Tao, R Haddadin, N Mathias, M Hussain Pharmaceutical research 29, 2766-2776, 2012 | 106 | 2012 |
Viscosity-lowering effect of amino acids and salts on highly concentrated solutions of two IgG1 monoclonal antibodies S Wang, N Zhang, T Hu, W Dai, X Feng, X Zhang, F Qian Molecular pharmaceutics 12 (12), 4478-4487, 2015 | 102 | 2015 |
Fabrication and characterization of controlled release poly(D,L‐lactide‐co‐glycolide) millirods F Qian, A Szymanski, J Gao Journal of Biomedical Materials Research: An Official Journal of The Society …, 2001 | 87 | 2001 |
Quantification of in vivo doxorubicin transport from PLGA millirods in thermoablated rat livers F Qian, N Stowe, EH Liu, GM Saidel, J Gao Journal of controlled release 91 (1-2), 157-166, 2003 | 75 | 2003 |
Targeting the oncogene KRAS mutant pancreatic cancer by synergistic blocking of lysosomal acidification and rapid drug release C Kong, Y Li, Z Liu, J Ye, Z Wang, L Zhang, W Kong, H Liu, C Liu, H Pang, ... Acs Nano 13 (4), 4049-4063, 2019 | 74 | 2019 |
Sodium lauryl sulfate competitively interacts with HPMC-AS and consequently reduces oral bioavailability of posaconazole/HPMC-AS amorphous solid dispersion Y Chen, S Wang, S Wang, C Liu, C Su, M Hageman, M Hussain, ... Molecular pharmaceutics 13 (8), 2787-2795, 2016 | 69 | 2016 |
Mechanistic investigation of Pluronic® based nano-crystalline drug-polymer solid dispersions F Qian, J Tao, S Desikan, M Hussain, RL Smith Pharmaceutical research 24, 1551-1560, 2007 | 69 | 2007 |
Moisture-induced amorphous phase separation of amorphous solid dispersions: molecular mechanism, microstructure, and its impact on dissolution performance H Chen, Y Pui, C Liu, Z Chen, CC Su, M Hageman, M Hussain, R Haskell, ... Journal of pharmaceutical sciences 107 (1), 317-326, 2018 | 67 | 2018 |
Stabilizing two IgG1 monoclonal antibodies by surfactants: balance between aggregation prevention and structure perturbation S Wang, G Wu, X Zhang, Z Tian, N Zhang, T Hu, W Dai, F Qian European journal of pharmaceutics and biopharmaceutics 114, 263-277, 2017 | 55 | 2017 |
Formulation and process design for a solid dosage form containing a spray-dried amorphous dispersion of ibipinabant MM Leane, W Sinclair, F Qian, R Haddadin, A Brown, M Tobyn, ... Pharmaceutical development and technology 18 (2), 359-366, 2013 | 55 | 2013 |
Membrane‐encased polymer millirods for sustained release of 5‐fluorouracil F Qian, N Nasongkla, J Gao Journal of Biomedical Materials Research: An Official Journal of The Society …, 2002 | 54 | 2002 |
In vivo drug distribution dynamics in thermoablated and normal rabbit livers from biodegradable polymers J Gao, F Qian, A Szymanski‐Exner, N Stowe, J Haaga Journal of Biomedical Materials Research: An Official Journal of The Society …, 2002 | 53 | 2002 |