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Sarah Doyle
Sarah Doyle
Clinical Medicine, Trinity College Dublin
在 tcd.ie 的电子邮件经过验证
标题
引用次数
引用次数
年份
Toll-like receptors: from the discovery of NFκB to new insights into transcriptional regulations in innate immunity
SL Doyle, LAJ O’Neill
Biochemical pharmacology 72 (9), 1102-1113, 2006
8202006
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
A Mansell, R Smith, SL Doyle, P Gray, JE Fenner, PJ Crack, SE Nicholson, ...
Nature immunology 7 (2), 148-155, 2006
6692006
Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer
LAJ O'Neill, CE Bryant, SL Doyle
Pharmacological reviews 61 (2), 177-197, 2009
5652009
NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
SL Doyle, M Campbell, E Ozaki, RG Salomon, A Mori, PF Kenna, ...
Nature medicine 18 (5), 791-798, 2012
4822012
Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectives
E Ozaki, M Campbell, SL Doyle
Journal of inflammation research, 15-27, 2015
4702015
Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor κB activation by Toll-like receptor 4
CA Jefferies, S Doyle, C Brunner, A Dunne, E Brint, C Wietek, E Walch, ...
Journal of Biological Chemistry 278 (28), 26258-26264, 2003
4082003
IL-10 inhibits miR-155 induction by toll-like receptors
CE McCoy, FJ Sheedy, JE Qualls, SL Doyle, SR Quinn, PJ Murray, ...
Journal of Biological Chemistry 285 (27), 20492-20498, 2010
3392010
MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction
P Gray, A Dunne, C Brikos, CA Jefferies, SL Doyle, LAJ O'Neill
Journal of Biological Chemistry 281 (15), 10489-10495, 2006
2712006
IL-1 family cytokine regulation of vascular permeability and angiogenesis
E Fahey, SL Doyle
Frontiers in Immunology 10, 1426, 2019
2242019
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway
EM Palsson-McDermott, SL Doyle, AF McGettrick, M Hardy, H Husebye, ...
Nature immunology 10 (6), 579-586, 2009
2232009
Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFκB activation by lipopolysaccharide
SL Doyle, CA Jefferies, LA O'Neill
Journal of Biological Chemistry 280 (25), 23496-23501, 2005
1722005
Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase
SL Doyle, CA Jefferies, C Feighery, LAJ O'Neill
Journal of Biological Chemistry 282 (51), 36953-36960, 2007
1602007
TRAM is required for TLR2 endosomal signaling to type I IFN induction
J Stack, SL Doyle, DJ Connolly, LS Reinert, KM O’Keeffe, RM McLoughlin, ...
The Journal of Immunology 193 (12), 6090-6102, 2014
1242014
IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration
SL Doyle, E Ozaki, K Brennan, MM Humphries, K Mulfaul, J Keaney, ...
Science translational medicine 6 (230), 230ra44-230ra44, 2014
1212014
NLRP3 inflammasome and pathobiology in AMD
L Celkova, SL Doyle, M Campbell
Journal of clinical medicine 4 (1), 172-192, 2015
1052015
Bruton’s tyrosine kinase mediates the synergistic signalling between TLR9 and the B cell receptor by regulating calcium and calmodulin
EF Kenny, SR Quinn, SL Doyle, PM Vink, H van Eenennaam, LAJ O’Neill
PloS one 8 (8), e74103, 2013
692013
The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation
SL Doyle, H Husebye, DJ Connolly, T Espevik, LA O'neill, AF McGettrick
Nature Communications 3 (1), 707, 2012
692012
Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor
H Yuan, CM Wilson, J Xia, SL Doyle, S Li, AM Fales, Y Liu, E Ozaki, ...
Nanoscale 6 (8), 4078-4082, 2014
642014
Low density granulocytes in ANCA vasculitis are heterogenous and hypo-responsive to anti-myeloperoxidase antibodies
A Ui Mhaonaigh, AM Coughlan, A Dwivedi, J Hartnett, J Cabral, B Moran, ...
Frontiers in immunology 10, 2603, 2019
592019
Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction
E Giannoudaki, YE Hernandez-Santana, K Mulfaul, SL Doyle, E Hams, ...
Nature communications 10 (1), 4003, 2019
592019
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