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Somaia Abdel Karim
Somaia Abdel Karim
Professor (Organic Chemistry) Therapeutic Chemistry Department, National Research Center
在 nrc.sci.eg 的电子邮件经过验证
标题
引用次数
引用次数
年份
Novel coumarin derivatives with expected biological activity
ZM Nofal, MI El-Zahar, SS Abd El-Karim
Molecules 5 (2), 99-113, 2000
3352000
Design, synthesis, biological evaluation and molecular docking studies of novel benzofuran–pyrazole derivatives as anticancer agents
SS Abd El-Karim, MM Anwar, NA Mohamed, T Nasr, SA Elseginy
Bioorganic chemistry 63, 1-12, 2015
902015
Novel benzimidazole derivatives as expected anticancer agents
ZM Nofal, EA Soliman, SS Abd El-Karim, MI El Zahar, AM Srour, ...
Acta Pol Pharm 68, 519-534, 2011
782011
New thiazol-hydrazono-coumarin hybrids targeting human cervical cancer cells: Synthesis, CDK2 inhibition, QSAR and molecular docking studies
SS Abd El-Karim, YM Syam, AM El Kerdawy, TM Abdelghany
Bioorganic chemistry 86, 80-96, 2019
712019
Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity
SS Abd El-Karim, HS Mohamed, MF Abdelhameed, AEGE Amr, ...
Bioorganic chemistry 111, 104827, 2021
652021
Synthesis, antitumor activity and molecular docking study of novel benzofuran-2-yl pyrazole pyrimidine derivatives
MI El-Zahar, SA El-Karim, ME Haiba, MA Khedr
Acta Pol Pharm Drug Res 68, 357-373, 2011
592011
Rational design and synthesis of new tetralin-sulfonamide derivatives as potent anti-diabetics and DPP-4 inhibitors: 2D & 3D QSAR, in vivo radiolabeling and bio distribution …
SS Abd El-Karim, MM Anwar, YM Syam, MA Nael, HF Ali, MA Motaleb
Bioorganic chemistry 81, 481-493, 2018
562018
Design, synthesis and anticervical cancer activity of new benzofuran–pyrazol-hydrazono-thiazolidin-4-one hybrids as potential EGFR inhibitors and apoptosis inducing agents
HAS Abbas, SS Abd El-Karim
Bioorganic chemistry 89, 103035, 2019
552019
Design, synthesis, biological evaluation, QSAR analysis and molecular modelling of new thiazol-benzimidazoles as EGFR inhibitors
AM Srour, NS Ahmed, SS Abd El-Karim, MM Anwar, SM El-Hallouty
Bioorganic & Medicinal Chemistry 28 (18), 115657, 2020
452020
A comparative study of the anticancer activity and PARP-1 inhibiting effect of benzofuran–pyrazole scaffold and its nano-sized particles in human breast cancer cells
MM Anwar, SS Abd El-Karim, AH Mahmoud, AEGE Amr, MA Al-Omar
Molecules 24 (13), 2413, 2019
422019
Kinase inhibitory activities and molecular docking of a novel series of anticancer pyrazole derivatives
ES Nossier, SS Abd El-Karim, NM Khalifa, AS El-Sayed, ESI Hassan, ...
Molecules 23 (12), 3074, 2018
412018
Synthesis and biological evaluation of new derivatives of thieno-thiazole and dihydrothiazolo-thiazole scaffolds integrated with a pyrazoline nucleus as anticancer and multi …
IMM Othman, ZM Alamshany, NY Tashkandi, MAM Gad-Elkareem, ...
RSC advances 12 (1), 561-577, 2022
342022
Synthesis and cytotoxicity screening of some novel benzofuranoyl-pyrazole derivatives against liver and cervix carcinoma cell lines
MI El-Zahar, A El-Karim, S Somaia, MM Anwar
South African Journal of Chemistry 62, 189-199, 2009
332009
Synthesis and cytotoxic evalution of some novel 6-(Benzofuran-yl)-4-(4-fluorophenyl) pyridines
HME El-Zahar MI, Abd El-Karim SS
World journal of chemistry 4 (2), 182-194, 2009
23*2009
Synthesis of some new benzimidazole-thiazole derivatives as anticancer agents
TJM ZM Nofal, EA Soliman, SS Abd El-Karim, MI El Zahar, AM Srour, S ...
J Heterocyclic Chemistry 51, 1797-1806, 2014
212014
Anti-Alzheimer activity of new coumarin-based derivatives targeting acetylcholinesterase inhibition
NN Kamel, HF Aly, GI Fouad, SS Abd El-Karim, MM Anwar, YM Syam, ...
RSC advances 13 (27), 18496-18510, 2023
202023
Synthesis and Molecular Modeling of New Benzimidazoles as Glutathione S-Transferase Inhibitors and Anticancer Agents
SS Abd El-Karim, MM Anwar, ER Zaki, SA Elseginy, ZM Nofal
Future Medicinal Chemistry 10 (2), 157-181, 2018
202018
Synthesis, antimicrobial and antioxidant activities of some novel cyclized naphthyl cyclohexanone derivatives
MI El-Zahar, SS Abd El-Karim, MM Anwar, EM Danial
Der Pharma Chem 2, 118-134, 2010
202010
New quinoxaline compounds as DPP-4 inhibitors and hypoglycemics: design, synthesis, computational and bio-distribution studies
YM Syam, MM Anwar, SS Abd El-Karim, SA Elseginy, BM Essa, TM Sakr
RSC advances 11 (58), 36989-37010, 2021
182021
Synthesis and anticancer evaluation of novel isoxazole/pyrazole derivatives
SM Abu Bakr, SS Abd El-Karim, MM Said, MM Youns
Research on Chemical Intermediates 42, 1387-1399, 2016
182016
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