Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators MJ Pikaart, F Recillas-Targa, G Felsenfeld Genes & development 12 (18), 2852-2862, 1998 | 524 | 1998 |
Position-effect protection and enhancer blocking by the chicken β-globin insulator are separable activities F Recillas-Targa, MJ Pikaart, B Burgess-Beusse, AC Bell, MD Litt, ... Proceedings of the National Academy of Sciences 99 (10), 6883-6888, 2002 | 496 | 2002 |
Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci MD Litt, M Simpson, F Recillas-Targa, MN Prioleau, G Felsenfeld The EMBO journal 20 (9), 2224-2235, 2001 | 441 | 2001 |
The insulation of genes from external enhancers and silencing chromatin B Burgess-Beusse, C Farrell, M Gaszner, M Litt, V Mutskov, ... Proceedings of the National Academy of Sciences 99 (suppl_4), 16433-16437, 2002 | 391 | 2002 |
CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53 R Saldaña-Meyer, E González-Buendía, G Guerrero, V Narendra, ... Genes & development 28 (7), 723-734, 2014 | 214 | 2014 |
Structural and functional conservation at the boundaries of the chicken β-globin domain N Saitoh, AC Bell, F Recillas-Targa, AG West, M Simpson, M Pikaart, ... The EMBO journal 19 (10), 2315-2322, 2000 | 198 | 2000 |
Multiple strategies for gene transfer, expression, knockdown, and chromatin influence in mammalian cell lines and transgenic animals F Recillas-Targa Molecular biotechnology 34, 337-354, 2006 | 155 | 2006 |
Epigenetic regulation of the human retinoblastoma tumor suppressor gene promoter by CTCF IA De la Rosa-Velazquez, H Rincón-Arano, L Benitez-Bribiesca, ... Cancer research 67 (6), 2577-2585, 2007 | 144 | 2007 |
Positional enhancer-blocking activity of the chicken β-globin insulator in transiently transfected cells F Recillas-Targa, AC Bell, G Felsenfeld Proceedings of the National Academy of Sciences 96 (25), 14354-14359, 1999 | 143 | 1999 |
Developing in 3D: the role of CTCF in cell differentiation RG Arzate-Mejía, F Recillas-Targa, VG Corces Development 145 (6), dev137729, 2018 | 138 | 2018 |
Transcriptional and epigenetic regulation of the p53 tumor suppressor gene R Saldaña-Meyer, F Recillas-Targa Epigenetics 6 (9), 1068-1077, 2011 | 128 | 2011 |
Cyclin D1 is transcriptionally down-regulated by ZO-2 via an E box and the transcription factor c-Myc M Huerta, R Muñoz, R Tapia, E Soto-Reyes, L Ramírez, F Recillas-Targa, ... Molecular biology of the cell 18 (12), 4826-4836, 2007 | 128 | 2007 |
Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes D Martin, C Pantoja, AF Miñán, C Valdes-Quezada, E Moltó, F Matesanz, ... Nature structural & molecular biology 18 (6), 708-714, 2011 | 124 | 2011 |
Epigenetic regulation of the human p53 gene promoter by the CTCF transcription factor in transformed cell lines E Soto-Reyes, F Recillas-Targa Oncogene 29 (15), 2217-2227, 2010 | 123 | 2010 |
Sequential chromatin immunoprecipitation protocol: ChIP-reChIP M Furlan-Magaril, H Rincón-Arano, F Recillas-Targa DNA-Protein Interactions: Principles and Protocols, Third Edition, 253-266, 2009 | 117 | 2009 |
Prospects and implications of using chromatin insulators in gene therapy and transgenesis F Recillas‐Targa, V Valadez‐Graham, CM Farrell Bioessays 26 (7), 796-807, 2004 | 115 | 2004 |
Mapping of structural and transcription-related matrix attachment sites in the α-globin gene domain of avian erythroblasts and erythrocytes G Farache, SV Razin, J Rzeszowska-Wolny, J Moreau, FR Targa, ... Molecular and cellular biology 10 (10), 5349-5358, 1990 | 94 | 1990 |
E6 and E7 oncoproteins from human papillomavirus type 16 induce activation of human transforming growth factor β 1 promoter throughout Sp1 recognition sequence O Peralta-Zaragoza, V Bermúdez-Morales, L Gutiérrez-Xicotencatl, ... Viral immunology 19 (3), 468-480, 2006 | 83 | 2006 |
Retrovirus silencer blocking by the cHS4 insulator is CTCF independent S Yao, CS Osborne, RR Bharadwaj, P Pasceri, T Sukonnik, D Pannell, ... Nucleic acids research 31 (18), 5317-5323, 2003 | 82 | 2003 |
Carbon regulation and the role in nature of the Escherichia coli penicillin acylase (pac) gene E Merino, P Balbás, F Recillas, B Becerril, F Valle, F Bolivar Molecular microbiology 6 (15), 2175-2182, 1992 | 78 | 1992 |