关注
Annabelle Lewis
Annabelle Lewis
Lecturer in Biomedical Sciences, Brunel University, London
在 brunel.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation
A Lewis, K Mitsuya, D Umlauf, P Smith, W Dean, J Walter, M Higgins, ...
Nature genetics 36 (12), 1291-1295, 2004
4932004
Co-evolution of X-chromosome inactivation and imprinting in mammals
W Reik, A Lewis
Nature Reviews Genetics 6 (5), 403-410, 2005
3322005
Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1
E Jaeger, S Leedham, A Lewis, S Segditsas, M Becker, PR Cuadrado, ...
Nature genetics 44 (6), 699-703, 2012
2902012
Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche
H Davis, S Irshad, M Bansal, H Rafferty, T Boitsova, C Bardella, E Jaeger, ...
Nature medicine 21 (1), 62-70, 2015
2842015
The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing
L Redrup, MR Branco, ER Perdeaux, C Krueger, A Lewis, F Santos, ...
Oxford University Press for The Company of Biologists Limited 136 (4), 525-530, 2009
2482009
Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer
IPM Tomlinson, LG Carvajal-Carmona, SE Dobbins, A Tenesa, AM Jones, ...
PLoS genetics 7 (6), e1002105, 2011
2392011
How imprinting centres work
A Lewis, W Reik
Cytogenetic and genome research 113 (1-4), 81-89, 2006
2362006
Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions
S Lopes, A Lewis, P Hajkova, W Dean, J Oswald, T Forné, A Murrell, ...
Human Molecular Genetics 12 (3), 295-305, 2003
2192003
FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation
R Babaei-Jadidi, N Li, A Saadeddin, B Spencer-Dene, A Jandke, ...
Journal of Experimental Medicine 208 (2), 295-312, 2011
1952011
Genomic imprinting: CTCF protects the boundaries
A Lewis, A Murrell
Current Biology 14 (7), R284-R286, 2004
1312004
Epigenetic dynamics of the Kcnq1 imprinted domain in the early embryo
A Lewis, K Green, C Dawson, L Redrup, KD Huynh, JT Lee, M Hemberger, ...
Oxford University Press for The Company of Biologists Limited 133 (21), 4203 …, 2006
1032006
A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts
SJ Leedham, P Rodenas-Cuadrado, K Howarth, A Lewis, S Mallappa, ...
Gut 62 (1), 83-93, 2013
1012013
Five endometrial cancer risk loci identified through genome-wide association analysis
THT Cheng, DJ Thompson, TA O'Mara, JN Painter, DM Glubb, S Flach, ...
Nature genetics 48 (6), 667-674, 2016
992016
The Apc1322T mouse develops severe polyposis associated with submaximal nuclear β-catenin expression
P Pollard, M Deheragoda, S Segditsas, A Lewis, A Rowan, K Howarth, ...
Gastroenterology 136 (7), 2204-2213. e13, 2009
802009
Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution
AM Baker, W Huang, XMM Wang, M Jansen, XJ Ma, J Kim, CM Anderson, ...
Nature Communications 8 (1), 1998, 2017
782017
Severe polyposis in Apc1322T mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5
A Lewis, S Segditsas, M Deheragoda, P Pollard, R Jeffery, E Nye, ...
Gut 59 (12), 1680-1686, 2010
742010
CRISPR-Cas9 causes chromosomal instability and rearrangements in cancer cell lines, detectable by cytogenetic methods
E Rayner, MA Durin, R Thomas, D Moralli, SM O'cathail, I Tomlinson, ...
The CRISPR journal 2 (6), 406-416, 2019
642019
Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines
H Davis, A Lewis, A Behrens, I Tomlinson
Gut 63 (5), 792-799, 2014
622014
A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding
A Lewis, L Freeman-Mills, E de la Calle-Mustienes, RM Giráldez-Pérez, ...
Cell reports 8 (4), 983-990, 2014
542014
Bone morphogenetic protein and Notch signalling crosstalk in poor‐prognosis, mesenchymal‐subtype colorectal cancer
S Irshad, M Bansal, P Guarnieri, H Davis, A Al Haj Zen, B Baran, ...
The Journal of Pathology 242 (2), 178-192, 2017
522017
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