Synthesis and function of 3-phosphorylated inositol lipids B Vanhaesebroeck, SJ Leevers, K Ahmadi, J Timms, R Katso, PC Driscoll, ... Annual review of biochemistry 70 (1), 535-602, 2001 | 2143 | 2001 |
Cellular function of phosphoinositide 3-kinases: implications for development, immunity, homeostasis, and cancer R Katso, K Okkenhaug, K Ahmadi, S White, J Timms, MD Waterfield Annual review of cell and developmental biology 17 (1), 615-675, 2001 | 1678 | 2001 |
Exploring the specificity of the PI3K family inhibitor LY294002 SI Gharbi, MJ Zvelebil, SJ Shuttleworth, T Hancox, N Saghir, JF Timms, ... Biochemical Journal 404 (1), 15-21, 2007 | 522 | 2007 |
Evaluation of two-dimensional differential gel electrophoresis for proteomic expression analysis of a model breast cancer cell system S Gharbi, P Gaffney, A Yang, MJ Zvelebil, R Cramer, MD Waterfield, ... Molecular & Cellular Proteomics 1 (2), 91-98, 2002 | 377 | 2002 |
Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2 ES Oh, H Gu, TM Saxton, JF Timms, S Hausdorff, EU Frevert, BB Kahn, ... Molecular and cellular biology 19 (4), 3205-3215, 1999 | 297 | 1999 |
Difference gel electrophoresis JF Timms, R Cramer Proteomics 8 (23‐24), 4886-4897, 2008 | 283 | 2008 |
Identification of major binding proteins and substrates for the SH2-containing protein tyrosine phosphatase SHP-1 in macrophages JF Timms, K Carlberg, H Gu, H Chen, S Kamatkar, MJS Nadler, ... Molecular and cellular biology 18 (7), 3838-3850, 1998 | 239 | 1998 |
Serum CA19-9 is significantly upregulated up to 2 years before diagnosis with pancreatic cancer: implications for early disease detection DP O'Brien, NS Sandanayake, C Jenkinson, A Gentry-Maharaj, ... Clinical Cancer Research 21 (3), 622-631, 2015 | 199 | 2015 |
Preanalytic influence of sample handling on SELDI-TOF serum protein profiles JF Timms, E Arslan-Low, A Gentry-Maharaj, Z Luo, D T’Jampens, ... Clinical chemistry 53 (4), 645-656, 2007 | 174 | 2007 |
AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D L Dumartin, HJ Whiteman, ME Weeks, D Hariharan, B Dmitrovic, ... Cancer research 71 (22), 7091-7102, 2011 | 159 | 2011 |
A time-resolved proteomic and prognostic map of COVID-19 V Demichev, P Tober-Lau, O Lemke, T Nazarenko, C Thibeault, ... Cell systems 12 (8), 780-794. e7, 2021 | 145 | 2021 |
The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1 Y Wu, MJS Nadler, LA Brennan, GD Gish, JF Timms, N Fusaki, ... Current biology 8 (18), 1009-1017, 1998 | 143 | 1998 |
Association between the cervicovaginal microbiome, BRCA1 mutation status, and risk of ovarian cancer: a case-control study NR Nené, D Reisel, A Leimbach, D Franchi, A Jones, I Evans, S Knapp, ... The lancet oncology 20 (8), 1171-1182, 2019 | 131 | 2019 |
Evaluation of serum CEA, CYFRA21-1 and CA125 for the early detection of colorectal cancer using longitudinal preclinical samples DS Thomas, EO Fourkala, S Apostolidou, R Gunu, A Ryan, I Jacobs, ... British journal of cancer 113 (2), 268-274, 2015 | 129 | 2015 |
Testing breast cancer serum biomarkers for early detection and prognosis in pre-diagnosis samples A Kazarian, O Blyuss, G Metodieva, A Gentry-Maharaj, A Ryan, ... British journal of cancer 116 (4), 501-508, 2017 | 125 | 2017 |
SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages JF Timms, KD Swanson, A Marie-Cardine, M Raab, CE Rudd, B Schraven, ... Current Biology 9 (16), 927-930, 1999 | 125 | 1999 |
The role of S100P in the invasion of pancreatic cancer cells is mediated through cytoskeletal changes and regulation of cathepsin D HJ Whiteman, ME Weeks, SE Dowen, S Barry, JF Timms, NR Lemoine, ... Cancer research 67 (18), 8633-8642, 2007 | 118 | 2007 |
Heat shock protein 27 is the major differentially phosphorylated protein involved in renal epithelial cellular stress response and controls focal adhesion organization and … M de Graauw, I Tijdens, R Cramer, S Corless, JF Timms, B Van De Water Journal of Biological Chemistry 280 (33), 29885-29898, 2005 | 115 | 2005 |
Proteomic analysis of redox‐and ErbB2‐dependent changes in mammary luminal epithelial cells using cysteine‐and lysine‐labelling two‐dimensional difference gel electrophoresis HL Chan, S Gharbi, PR Gaffney, R Cramer, MD Waterfield, JF Timms Proteomics 5 (11), 2908-2926, 2005 | 111 | 2005 |
Effects of ErbB-2 overexpression on mitogenic signalling and cell cycle progression in human breast luminal epithelial cells JF Timms, SL White, MJ O'Hare, MD Waterfield Oncogene 21 (43), 6573-6586, 2002 | 107 | 2002 |