Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band J Frigola, J Song, C Stirzaker, RA Hinshelwood, MA Peinado, SJ Clark Nature genetics 38 (5), 540-549, 2006 | 456 | 2006 |
Identification and resolution of artifacts in bisulfite sequencing PM Warnecke, C Stirzaker, J Song, C Grunau, JR Melki, SJ Clark Methods 27 (2), 101-107, 2002 | 395 | 2002 |
Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells C Stirzaker, JZ Song, B Davidson, SJ Clark Cancer research 64 (11), 3871-3877, 2004 | 276 | 2004 |
Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG sequence coverage bias SS Nair, MW Coolen, C Stirzaker, JZ Song, AL Statham, D Strbenac, ... Epigenetics 6 (1), 34-44, 2011 | 253 | 2011 |
Regional activation of the cancer genome by long-range epigenetic remodeling SA Bert, MD Robinson, D Strbenac, AL Statham, JZ Song, T Hulf, ... Cancer cell 23 (1), 9-22, 2013 | 232 | 2013 |
Acetylation of H2A. Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer F Valdés-Mora, JZ Song, AL Statham, D Strbenac, MD Robinson, SS Nair, ... Genome research 22 (2), 307-321, 2012 | 225 | 2012 |
Methylome sequencing in triple-negative breast cancer reveals distinct methylation clusters with prognostic value C Stirzaker, E Zotenko, JZ Song, W Qu, SS Nair, WJ Locke, A Stone, ... Nature communications 6 (1), 5899, 2015 | 221 | 2015 |
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity MW Coolen, C Stirzaker, JZ Song, AL Statham, Z Kassir, CS Moreno, ... Nature cell biology 12 (3), 235-246, 2010 | 215 | 2010 |
Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells JZ Song, C Stirzaker, J Harrison, JR Melki, SJ Clark Oncogene 21 (7), 1048-1061, 2002 | 209 | 2002 |
Bisulfite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq) directly informs methylation status of histone-modified DNA AL Statham, MD Robinson, JZ Song, MW Coolen, C Stirzaker, SJ Clark Genome research 22 (6), 1120-1127, 2012 | 208 | 2012 |
Evaluation of affinity-based genome-wide DNA methylation data: effects of CpG density, amplification bias, and copy number variation MD Robinson, C Stirzaker, AL Statham, MW Coolen, JZ Song, SS Nair, ... Genome research 20 (12), 1719-1729, 2010 | 147 | 2010 |
Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer Q Du, SA Bert, NJ Armstrong, CE Caldon, JZ Song, SS Nair, CM Gould, ... Nature communications 10 (1), 416, 2019 | 114 | 2019 |
Epigenetic-induced repression of microRNA-205 is associated with MED1 activation and a poorer prognosis in localized prostate cancer T Hulf, T Sibbritt, ED Wiklund, K Patterson, JZ Song, C Stirzaker, W Qu, ... Oncogene 32 (23), 2891-2899, 2013 | 109 | 2013 |
Enduring epigenetic landmarks define the cancer microenvironment R Pidsley, MG Lawrence, E Zotenko, B Niranjan, A Statham, J Song, ... Genome research 28 (5), 625-638, 2018 | 93 | 2018 |
Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome … RA Hinshelwood, JR Melki, LI Huschtscha, C Paul, JZ Song, C Stirzaker, ... Human molecular genetics 18 (16), 3098-3109, 2009 | 92 | 2009 |
Acetylated histone variant H2A. Z is involved in the activation of neo-enhancers in prostate cancer F Valdés-Mora, CM Gould, Y Colino-Sanguino, W Qu, JZ Song, KM Taylor, ... Nature Communications 8 (1), 1346, 2017 | 86 | 2017 |
Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation NC Wong, LH Wong, JM Quach, P Canham, JM Craig, JZ Song, SJ Clark, ... PLoS genetics 2 (2), e17, 2006 | 81 | 2006 |
Pathogenic NPHP5 mutations impair protein interaction with Cep290, a prerequisite for ciliogenesis M Barbelanne, J Song, M Ahmadzai, WY Tsang Human Molecular Genetics 22 (12), 2482-2494, 2013 | 80 | 2013 |
DNA hypermethylation encroachment at CpG island borders in cancer is predisposed by H3K4 monomethylation patterns K Skvortsova, E Masle-Farquhar, PL Luu, JZ Song, W Qu, E Zotenko, ... Cancer cell 35 (2), 297-314. e8, 2019 | 79 | 2019 |
Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer C Stirzaker, JZ Song, W Ng, Q Du, NJ Armstrong, WJ Locke, AL Statham, ... Oncogene 36 (10), 1328-1338, 2017 | 79 | 2017 |