Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA JD Lewis, RR Meehan, WJ Henzel, I Maurer-Fogy, P Jeppesen, F Klein, ... Cell 69 (6), 905-914, 1992 | 1692 | 1992 |
Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs RR Meehan, JD Lewis, S McKay, EL Kleiner, AP Bird Cell 58 (3), 499-507, 1989 | 929 | 1989 |
Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2 X Nan, RR Meehan, A Bird Nucleic acids research 21 (21), 4886-4892, 1993 | 779 | 1993 |
Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA R Meehan, JD Lewis, AP Bird Nucleic acids research 20 (19), 5085-5092, 1992 | 671 | 1992 |
Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration A Raven, WY Lu, TY Man, S Ferreira-Gonzalez, E O’Duibhir, BJ Dwyer, ... Nature 547 (7663), 350-354, 2017 | 492 | 2017 |
Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes CE Nestor, R Ottaviano, J Reddington, D Sproul, D Reinhardt, D Dunican, ... Genome research 22 (3), 467-477, 2012 | 463 | 2012 |
Senescent cells harbour features of the cancer epigenome HA Cruickshanks, T McBryan, DM Nelson, ND VanderKraats, PP Shah, ... Nature cell biology 15 (12), 1495-1506, 2013 | 346 | 2013 |
A component of the transcriptional represser MeCP1 shares a motif with DNA methyltransferase and HRX proteins SH Cross, RR Meehan, X Nan, A Bird Nature genetics 16 (3), 256-259, 1997 | 345 | 1997 |
Effect of limited DNA methylation reprogramming in the normal sheep embryo on somatic cell nuclear transfer N Beaujean, J Taylor, J Gardner, I Wilmut, R Meehan, L Young Biology of reproduction 71 (1), 185-193, 2004 | 302 | 2004 |
Non-conservation of mammalian preimplantation methylation dynamics N Beaujean, G Hartshorne, J Cavilla, J Taylor, J Gardner, I Wilmut, ... Current Biology 14 (7), R266-R267, 2004 | 284 | 2004 |
Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA C Nestor, A Ruzov, RR Meehan, DS Dunican Biotechniques 48 (4), 317-319, 2010 | 263 | 2010 |
Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes JP Reddington, SM Perricone, CE Nestor, J Reichmann, NA Youngson, ... Genome biology 14, 1-17, 2013 | 261 | 2013 |
Pattern of serum protein gene expression in mouse visceral yolk sac and foetal liver. RR Meehan, DP Barlow, RE Hill, BL Hogan, ND Hastie The EMBO journal 3 (8), 1881-1885, 1984 | 208 | 1984 |
Modules, networks and systems medicine for understanding disease and aiding diagnosis M Gustafsson, CE Nestor, H Zhang, AL Barabási, S Baranzini, S Brunak, ... Genome medicine 6, 1-11, 2014 | 200 | 2014 |
Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems CE Nestor, R Ottaviano, D Reinhardt, HA Cruickshanks, HK Mjoseng, ... Genome biology 16, 1-17, 2015 | 186 | 2015 |
Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns D Sproul, RR Kitchen, CE Nestor, JM Dixon, AH Sims, DJ Harrison, ... Genome biology 13, 1-16, 2012 | 186 | 2012 |
Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer D Sproul, C Nestor, J Culley, JH Dickson, JM Dixon, DJ Harrison, ... Proceedings of the National Academy of Sciences 108 (11), 4364-4369, 2011 | 180 | 2011 |
Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions JJ Cole, NA Robertson, MI Rather, JP Thomson, T McBryan, D Sproul, ... Genome biology 18, 1-16, 2017 | 177 | 2017 |
Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline JA Hackett, JP Reddington, CE Nestor, DS Dunican, MR Branco, ... Development 139 (19), 3623-3632, 2012 | 173 | 2012 |
HP1 binding to native chromatin in vitro is determined by the hinge region and not by the chromodomain RR Meehan, CF Kao, S Pennings The EMBO journal, 2003 | 173 | 2003 |